SA518400567B1 - جهاز وطرق لتتبع تنبؤي لبؤرة - Google Patents

جهاز وطرق لتتبع تنبؤي لبؤرة

Info

Publication number
SA518400567B1
SA518400567B1 SA518400567A SA518400567A SA518400567B1 SA 518400567 B1 SA518400567 B1 SA 518400567B1 SA 518400567 A SA518400567 A SA 518400567A SA 518400567 A SA518400567 A SA 518400567A SA 518400567 B1 SA518400567 B1 SA 518400567B1
Authority
SA
Saudi Arabia
Prior art keywords
sample
stage
location
optical stage
optical
Prior art date
Application number
SA518400567A
Other languages
English (en)
Inventor
اشكان ارينبور
سيمون برينس
دوستين بلير
جون بيلى
شونجونج زهو ( الين)
ميريك سى سيو
اكسيانجلينج( ستيف) شين
دانيلو كونديلو
ستانلى اس هونج
Original Assignee
.الومينا، إنك
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by .الومينا، إنك filed Critical .الومينا، إنك
Publication of SA518400567B1 publication Critical patent/SA518400567B1/ar

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/006—Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/16—Beam splitting or combining systems used as aids for focusing
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/02—Mountings, adjusting means, or light-tight connections, for optical elements for lenses
    • G02B7/04—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification
    • G02B7/09—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification adapted for automatic focusing or varying magnification
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/02—Mountings, adjusting means, or light-tight connections, for optical elements for lenses
    • G02B7/04—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification
    • G02B7/10—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification by relative axial movement of several lenses, e.g. of varifocal objective lens
    • G02B7/102—Mountings, adjusting means, or light-tight connections, for optical elements for lenses with mechanism for focusing or varying magnification by relative axial movement of several lenses, e.g. of varifocal objective lens controlled by a microcomputer

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
  • Automatic Focus Adjustment (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Health & Medical Sciences (AREA)
  • Studio Devices (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Prostheses (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Focusing (AREA)
  • Lens Barrels (AREA)

Abstract

يتعلق الاختراع الحالي بنظام تصوير يمكن أن يتضمن منصة عينة sample stage تشتمل على سطح لدعم حاوية عينة، يكون بحاوية العينة مجموعة من مواقع العينة؛ منصة ضوئية optical stage بها عدسة شيئية objective lens، تكون المنصة الضوئية قابلة للوضع بالنسبة لمنصة العينة لتصوير عينات عند مواقع العينة؛ مشغل مقترن مادياً بواحدة على الأقل من منصة العينة والمنصة الضوئية لتحريك منصة العينة بالنسبة للمنصة الضوئية لتركيز المنصة الضوئية على موقع عينة حالي؛ ودائرة توجيه drive circuit لتحديد إعداد بؤرة لموقع عينة تالي ولإمداد إشارة توجيه drive signal إلى المشغل actuator قبل وضع المنصة الضوئية لتصوير عينة عند موقع العينة التالي، حيث يتم تحديد متغير واحد على الأقل لإشارة التوجيه باستخدام تباين بين إعداد بؤرة لموقع العينة الحالي وإعداد البؤرة المحدد لموقع العينة التالي. شكل1
SA518400567A 2017-01-05 2018-12-02 جهاز وطرق لتتبع تنبؤي لبؤرة SA518400567B1 (ar)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762442947P 2017-01-05 2017-01-05
GBGB1704770.5A GB201704770D0 (en) 2017-01-05 2017-03-24 Predictive focus tracking apparatus and methods
PCT/IB2017/058383 WO2018127769A1 (en) 2017-01-05 2017-12-22 Predictive focus tracking apparatus and methods

Publications (1)

Publication Number Publication Date
SA518400567B1 true SA518400567B1 (ar) 2022-03-20

Family

ID=58687922

Family Applications (1)

Application Number Title Priority Date Filing Date
SA518400567A SA518400567B1 (ar) 2017-01-05 2018-12-02 جهاز وطرق لتتبع تنبؤي لبؤرة

Country Status (17)

Country Link
US (2) US11054624B2 (ar)
EP (1) EP3566088B1 (ar)
JP (1) JP7050701B2 (ar)
KR (1) KR102551459B1 (ar)
CN (1) CN109313329B (ar)
AU (1) AU2017390821B2 (ar)
BR (1) BR112018076996B1 (ar)
CA (1) CA3022894C (ar)
GB (1) GB201704770D0 (ar)
IL (2) IL262707B2 (ar)
MX (1) MX2019007874A (ar)
MY (1) MY195238A (ar)
RU (1) RU2710004C1 (ar)
SA (1) SA518400567B1 (ar)
SG (1) SG11201811328PA (ar)
TW (1) TWI772348B (ar)
WO (1) WO2018127769A1 (ar)

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GB201704770D0 (en) * 2017-01-05 2017-05-10 Illumina Inc Predictive focus tracking apparatus and methods
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JP6960352B2 (ja) * 2018-02-20 2021-11-05 株式会社日立ハイテク ステージ装置、及び荷電粒子線装置
US20230088338A1 (en) 2021-09-10 2023-03-23 Illumina, Inc. Sequencer focus quality metrics and focus tracking for periodically patterned surfaces
CN115086563B (zh) * 2022-07-27 2022-11-15 南方科技大学 基于SerialEM的单颗粒数据收集方法和装置
CN115576075B (zh) * 2022-11-21 2023-03-14 上海隐冠半导体技术有限公司 一种自动对焦系统和方法

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Also Published As

Publication number Publication date
KR20190095110A (ko) 2019-08-14
MY195238A (en) 2023-01-11
CN109313329A (zh) 2019-02-05
JP7050701B2 (ja) 2022-04-08
AU2017390821B2 (en) 2021-10-28
IL262707B2 (en) 2023-09-01
SG11201811328PA (en) 2019-01-30
WO2018127769A1 (en) 2018-07-12
TW201841020A (zh) 2018-11-16
IL262707B1 (en) 2023-05-01
KR102551459B1 (ko) 2023-07-04
MX2019007874A (es) 2019-11-05
IL301850A (en) 2023-06-01
US11977213B2 (en) 2024-05-07
CN109313329B (zh) 2021-11-09
AU2017390821A1 (en) 2018-11-22
EP3566088B1 (en) 2024-01-31
RU2710004C1 (ru) 2019-12-23
EP3566088A1 (en) 2019-11-13
US11054624B2 (en) 2021-07-06
BR112018076996A2 (pt) 2019-04-02
EP3566088C0 (en) 2024-01-31
CA3022894C (en) 2020-10-27
US20180188514A1 (en) 2018-07-05
IL262707A (en) 2018-12-31
BR112018076996B1 (pt) 2022-02-22
TWI772348B (zh) 2022-08-01
EP3566088A4 (en) 2020-08-12
NZ747882A (en) 2021-02-26
GB201704770D0 (en) 2017-05-10
JP2020505625A (ja) 2020-02-20
US20210294083A1 (en) 2021-09-23
CA3022894A1 (en) 2018-07-12

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