AU2017334035B2 - Treatment of prostate cancer - Google Patents

Treatment of prostate cancer Download PDF

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Publication number
AU2017334035B2
AU2017334035B2 AU2017334035A AU2017334035A AU2017334035B2 AU 2017334035 B2 AU2017334035 B2 AU 2017334035B2 AU 2017334035 A AU2017334035 A AU 2017334035A AU 2017334035 A AU2017334035 A AU 2017334035A AU 2017334035 B2 AU2017334035 B2 AU 2017334035B2
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AU
Australia
Prior art keywords
oral
administration
once
disclosure
subject
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2017334035A
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English (en)
Other versions
AU2017334035A1 (en
Inventor
Brendan Mark JOHNSON
David B. Maclean
Paul N. Mudd Jr.
Vijaykumar Reddy RAJASEKHAR
Lynn Seely
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Switzerland GmbH
Takeda Pharmaceutical Co Ltd
Original Assignee
Sumitomo Pharma Switzerland GmbH
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60915459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2017334035(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Pharma Switzerland GmbH, Takeda Pharmaceutical Co Ltd filed Critical Sumitomo Pharma Switzerland GmbH
Publication of AU2017334035A1 publication Critical patent/AU2017334035A1/en
Application granted granted Critical
Publication of AU2017334035B2 publication Critical patent/AU2017334035B2/en
Priority to AU2023201047A priority Critical patent/AU2023201047B2/en
Assigned to TAKEDA PHARMACEUTICAL COMPANY LIMITED, SUMITOMO PHARMA SWITZERLAND GMBH reassignment TAKEDA PHARMACEUTICAL COMPANY LIMITED Request to Amend Deed and Register Assignors: MYOVANT SCIENCES GMBH, TAKEDA PHARMACEUTICAL COMPANY LIMITED
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2017334035A 2016-09-30 2017-09-29 Treatment of prostate cancer Active AU2017334035B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023201047A AU2023201047B2 (en) 2016-09-30 2023-02-22 Treatment of prostate cancer

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662402004P 2016-09-30 2016-09-30
US201662402150P 2016-09-30 2016-09-30
US62/402,004 2016-09-30
US62/402,150 2016-09-30
PCT/EP2017/074849 WO2018060463A2 (en) 2016-09-30 2017-09-29 Treatment of prostate cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2023201047A Division AU2023201047B2 (en) 2016-09-30 2023-02-22 Treatment of prostate cancer

Publications (2)

Publication Number Publication Date
AU2017334035A1 AU2017334035A1 (en) 2019-05-16
AU2017334035B2 true AU2017334035B2 (en) 2022-11-24

Family

ID=60915459

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2017334035A Active AU2017334035B2 (en) 2016-09-30 2017-09-29 Treatment of prostate cancer
AU2023201047A Active AU2023201047B2 (en) 2016-09-30 2023-02-22 Treatment of prostate cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2023201047A Active AU2023201047B2 (en) 2016-09-30 2023-02-22 Treatment of prostate cancer

Country Status (21)

Country Link
US (8) US10449191B2 (enExample)
EP (2) EP3518932B1 (enExample)
JP (1) JP7062673B2 (enExample)
CN (1) CN110248661A (enExample)
AU (2) AU2017334035B2 (enExample)
BR (1) BR112019006228A2 (enExample)
CA (1) CA3038875A1 (enExample)
DK (1) DK3518932T3 (enExample)
ES (1) ES3002857T3 (enExample)
FI (1) FI3518932T3 (enExample)
HR (1) HRP20241740T1 (enExample)
HU (1) HUE070578T2 (enExample)
IL (3) IL308528A (enExample)
LT (1) LT3518932T (enExample)
MA (1) MA46361A (enExample)
MX (2) MX2019003733A (enExample)
NZ (1) NZ752918A (enExample)
PL (1) PL3518932T3 (enExample)
PT (1) PT3518932T (enExample)
SI (1) SI3518932T1 (enExample)
WO (1) WO2018060463A2 (enExample)

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Publication number Priority date Publication date Assignee Title
WO2014051164A2 (en) 2012-09-28 2014-04-03 Takeda Pharmaceutical Company Limited Production method of thienopyrimidine derivative
JP7062673B2 (ja) 2016-09-30 2022-05-06 ミオバント サイエンシズ ゲーエムベーハー 前立腺がんの治療
HRP20220708T4 (hr) 2016-09-30 2025-04-25 Sumitomo Pharma Switzerland Gmbh Postupci liječenja fibroida maternice i endometrioze
CN110194776B (zh) * 2019-06-27 2021-05-28 四川伊诺达博医药科技有限公司 一种瑞卢戈利的合成方法
WO2021069711A1 (en) * 2019-10-10 2021-04-15 Myovant Sciences Gmbh Crystalline forms of n-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo- 1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'- methoxyurea
CN115175912B (zh) * 2019-10-10 2025-04-11 住友制药瑞士有限公司 N-(4-(1-(2,6-二氟苄基)-5-((二甲基氨基)甲基)-3-(6-甲氧基-3-哒嗪基)-2,4-二氧代-1,2,3,4-四氢噻吩并[2,3-d]嘧啶-6-基)苯基)-n′-甲氧基脲的结晶溶剂化形式
AU2021278303A1 (en) 2020-05-29 2023-02-09 Sumitomo Pharma Switzerland Gmbh Combination solid oral dosage forms of gonadotropin-releasing hormone antagonists
EP4232164A4 (en) * 2020-10-20 2025-01-15 Baylor College of Medicine MULTIPLEX METABOLIC MARKERS IN PLASMA FOR EARLY DETECTION OF AFRICAN AMERICAN PROSTATE CANCER
EP4243829A1 (en) 2020-11-11 2023-09-20 Myovant Sciences GmbH Methods of administering relugolix
CN118451082A (zh) 2021-10-18 2024-08-06 住友制药瑞士有限公司 N-(4-(1-(2,6-二氟苄基)-5-((二甲基氨基)甲基)-3-(6-甲氧基-3-哒嗪基)-2,4-二氧代-1,2,3,4-四氢噻吩并[2,3-d]嘧啶-6-基)苯基)-N'-甲氧基脲的乙醇溶剂化物的结晶形式
WO2023152611A1 (en) * 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
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FR2710637B1 (fr) 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
US6297379B1 (en) 1999-03-24 2001-10-02 Takeda Chemical Industries, Ltd. Thienopyrimidine compounds, their production and use
TWI225863B (en) 1999-03-24 2005-01-01 Takeda Chemical Industries Ltd Thienopyrimidine compounds, their production and use
WO2001064683A1 (en) 2000-02-29 2001-09-07 Takeda Chemical Industries, Ltd. Processes for the production of thienopyrimidine derivatives
WO2003057689A1 (en) 2002-01-02 2003-07-17 Fujisawa Pharmaceutical Co., Ltd. Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them
US7569570B2 (en) 2002-01-30 2009-08-04 Takeda Pharmaceutical Company Limited Thienopyrimidines, process for preparing the same and use thereof
DK1480679T3 (da) 2002-02-26 2007-09-03 Astrazeneca Ab Farmaceutisk formulering af iressa, der omfatter et vandoplöseligt cellulosederivat
PL214756B1 (pl) 2003-01-29 2013-09-30 Takeda Pharmaceutical Zwiazki tienopirymidynowe, kompozycja farmaceutyczna zawierajaca te zwiazki oraz ich zastosowanie
DK1646389T3 (da) 2003-07-07 2009-01-05 Neurocrine Biosciences Inc Pyrimidin-2,4-dionderivater som gonadotropinfrigörende hormonreceptorantagonister
JPWO2007011072A1 (ja) 2005-07-22 2009-02-05 武田薬品工業株式会社 早発排卵の防止剤
PE20090044A1 (es) 2007-04-06 2009-01-23 Neurocrine Biosciences Inc Antagonistas del receptor de la hormona liberadora de gonadotropina y procedimientos relacionados con los mismos
WO2009062087A1 (en) 2007-11-07 2009-05-14 Neurocrine Biosciences, Inc. Processes for the preparation of uracil derivatives
TWI539959B (zh) 2008-02-11 2016-07-01 菲瑞茵國際中心股份有限公司 治療轉移階段攝護腺癌的方法
EP2329823A4 (en) 2008-09-03 2013-04-03 Takeda Pharmaceutical PROCESS FOR INCREASING THE ABSORPTION ABILITY OF A PREPARATION AND PREPARATION WITH INCREASED ABSORPTION ABILITY
WO2014051164A2 (en) 2012-09-28 2014-04-03 Takeda Pharmaceutical Company Limited Production method of thienopyrimidine derivative
EP3185881B1 (en) 2014-08-26 2022-03-09 Betanien Hospital Methods, agents and compositions for treatment of inflammatory conditions
EP4454708A3 (en) 2015-02-26 2024-11-13 Takeda Pharmaceutical Company Limited A tablet comprising a methoxyurea derivative and mannitol particles
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HRP20220708T4 (hr) 2016-09-30 2025-04-25 Sumitomo Pharma Switzerland Gmbh Postupci liječenja fibroida maternice i endometrioze
JP7062673B2 (ja) 2016-09-30 2022-05-06 ミオバント サイエンシズ ゲーエムベーハー 前立腺がんの治療

Non-Patent Citations (2)

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Also Published As

Publication number Publication date
US20250332166A1 (en) 2025-10-30
PL3518932T3 (pl) 2025-04-07
AU2017334035A1 (en) 2019-05-16
HUE070578T2 (hu) 2025-06-28
US20240358700A1 (en) 2024-10-31
EP3518932B1 (en) 2024-11-13
US20220401443A1 (en) 2022-12-22
US20250082632A1 (en) 2025-03-13
AU2023201047A1 (en) 2023-03-23
ES3002857T3 (en) 2025-03-07
LT3518932T (lt) 2025-02-10
NZ752918A (en) 2022-09-30
HRP20241740T1 (hr) 2025-02-28
IL265697A (en) 2019-05-30
SI3518932T1 (sl) 2025-03-31
US12144809B1 (en) 2024-11-19
US20190224196A1 (en) 2019-07-25
EP3518932A2 (en) 2019-08-07
US10449191B2 (en) 2019-10-22
US12336990B2 (en) 2025-06-24
FI3518932T3 (fi) 2025-02-03
MA46361A (fr) 2021-03-31
JP7062673B2 (ja) 2022-05-06
EP4520398A3 (en) 2025-04-02
EP4520398A2 (en) 2025-03-12
CN110248661A (zh) 2019-09-17
WO2018060463A3 (en) 2018-05-11
US20210205303A1 (en) 2021-07-08
US10786501B2 (en) 2020-09-29
DK3518932T3 (da) 2025-01-27
JP2019529574A (ja) 2019-10-17
US20250057839A1 (en) 2025-02-20
AU2023201047B2 (en) 2025-04-03
MX2023001468A (es) 2023-03-03
US11583526B2 (en) 2023-02-21
IL308528A (en) 2024-01-01
CA3038875A1 (en) 2018-04-05
US12097198B2 (en) 2024-09-24
MX2019003733A (es) 2019-09-26
IL265697B1 (en) 2023-03-01
IL300071A (en) 2023-03-01
PT3518932T (pt) 2025-01-16
US20200129507A1 (en) 2020-04-30
IL265697B2 (en) 2023-07-01
WO2018060463A2 (en) 2018-04-05
BR112019006228A2 (pt) 2019-06-18

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
HB Alteration of name in register

Owner name: SUMITOMO PHARMA SWITZERLAND GMBH

Free format text: FORMER NAME(S): TAKEDA PHARMACEUTICAL COMPANY LIMITED; MYOVANT SCIENCES GMBH

Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Free format text: FORMER NAME(S): TAKEDA PHARMACEUTICAL COMPANY LIMITED; MYOVANT SCIENCES GMBH