DK3518932T3 - Behandling af prostatacancer - Google Patents

Behandling af prostatacancer Download PDF

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Publication number
DK3518932T3
DK3518932T3 DK17823017.3T DK17823017T DK3518932T3 DK 3518932 T3 DK3518932 T3 DK 3518932T3 DK 17823017 T DK17823017 T DK 17823017T DK 3518932 T3 DK3518932 T3 DK 3518932T3
Authority
DK
Denmark
Prior art keywords
prostate cancer
cancer treatment
treatment
prostate
cancer
Prior art date
Application number
DK17823017.3T
Other languages
Danish (da)
English (en)
Inventor
Brendan Mark Johnson
Lynn Seely
Vijaykumar Reddy Rajasekhar
David B Maclean
Hélène M Faessel
Paul N Mudd
Original Assignee
Takeda Pharmaceuticals Co
Sumitomo Pharma Switzerland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60915459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3518932(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co, Sumitomo Pharma Switzerland Gmbh filed Critical Takeda Pharmaceuticals Co
Application granted granted Critical
Publication of DK3518932T3 publication Critical patent/DK3518932T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41661,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK17823017.3T 2016-09-30 2017-09-29 Behandling af prostatacancer DK3518932T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662402004P 2016-09-30 2016-09-30
US201662402150P 2016-09-30 2016-09-30
PCT/EP2017/074849 WO2018060463A2 (en) 2016-09-30 2017-09-29 Treatment of prostate cancer

Publications (1)

Publication Number Publication Date
DK3518932T3 true DK3518932T3 (da) 2025-01-27

Family

ID=60915459

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17823017.3T DK3518932T3 (da) 2016-09-30 2017-09-29 Behandling af prostatacancer

Country Status (21)

Country Link
US (8) US10449191B2 (enExample)
EP (2) EP3518932B1 (enExample)
JP (1) JP7062673B2 (enExample)
CN (1) CN110248661A (enExample)
AU (2) AU2017334035B2 (enExample)
BR (1) BR112019006228A2 (enExample)
CA (1) CA3038875A1 (enExample)
DK (1) DK3518932T3 (enExample)
ES (1) ES3002857T3 (enExample)
FI (1) FI3518932T3 (enExample)
HR (1) HRP20241740T1 (enExample)
HU (1) HUE070578T2 (enExample)
IL (3) IL308528A (enExample)
LT (1) LT3518932T (enExample)
MA (1) MA46361A (enExample)
MX (2) MX2019003733A (enExample)
NZ (1) NZ752918A (enExample)
PL (1) PL3518932T3 (enExample)
PT (1) PT3518932T (enExample)
SI (1) SI3518932T1 (enExample)
WO (1) WO2018060463A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20190729T1 (hr) 2012-09-28 2019-06-14 Takeda Pharmaceutical Company Limited Metoda proizvodnje derivata tienopirimidina
WO2018060501A2 (en) 2016-09-30 2018-04-05 Myovant Sciences Gmbh Methods of treating uterine fibroids and endometriosis
EP3518932B1 (en) 2016-09-30 2024-11-13 Sumitomo Pharma Switzerland GmbH Treatment of prostate cancer
CN110194776B (zh) * 2019-06-27 2021-05-28 四川伊诺达博医药科技有限公司 一种瑞卢戈利的合成方法
EP4041738A1 (en) * 2019-10-10 2022-08-17 Myovant Sciences GmbH Crystalline solvated forms of n-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4- tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
CN115279769A (zh) * 2019-10-10 2022-11-01 梦欧文科学有限责任公司 N-(4-(1-(2,6-二氟苄基)-5-((二甲基氨基)甲基)-3-(6-甲氧基-3-哒嗪基)-2,4-二氧代-1,2,3,4-四氢噻吩并[2,3-d]嘧啶-6-基)苯基)-n’-甲氧基脲的结晶形式
AU2021278303A1 (en) 2020-05-29 2023-02-09 Sumitomo Pharma Switzerland Gmbh Combination solid oral dosage forms of gonadotropin-releasing hormone antagonists
US20230384316A1 (en) * 2020-10-20 2023-11-30 Baylor College Of Medicine Multiplex metabolic markers in plasma for early detection of african american prostate cancer
EP4243829A1 (en) * 2020-11-11 2023-09-20 Myovant Sciences GmbH Methods of administering relugolix
WO2023066941A1 (en) 2021-10-18 2023-04-27 Myovant Sciences Gmbh Crystalline form of an ethanol solvate of n-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
WO2023152611A1 (en) * 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2710637B1 (fr) 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
RU2233284C2 (ru) 1999-03-24 2004-07-27 Такеда Кемикал Индастриз, Лтд. Тиенопиримидиновые производные, способ их получения, фармацевтическая композиция и способ антагонизации гонадотропин-рилизинг гормона
TWI225863B (en) 1999-03-24 2005-01-01 Takeda Chemical Industries Ltd Thienopyrimidine compounds, their production and use
AU2001234188A1 (en) 2000-02-29 2001-09-12 Takeda Chemical Industries Ltd. Processes for the production of thienopyrimidine derivatives
US20050043315A1 (en) 2002-01-02 2005-02-24 Hideo Tsutsumi Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them
WO2003064429A1 (en) 2002-01-30 2003-08-07 Takeda Chemical Industries, Ltd. Thienopyrimidines, process for preparing the same and use thereof
DK1480679T3 (da) 2002-02-26 2007-09-03 Astrazeneca Ab Farmaceutisk formulering af iressa, der omfatter et vandoplöseligt cellulosederivat
KR101074462B1 (ko) 2003-01-29 2011-10-18 다케다 야쿠힌 고교 가부시키가이샤 티에노피리미딘 화합물 및 그 용도
KR101139148B1 (ko) 2003-07-07 2012-04-26 뉴로크린 바이오사이언시즈 인코퍼레이티드 고나도트로핀-방출 호르몬 수용체 길항제로서의피리미딘-2,4-디온 유도체
NZ566038A (en) 2005-07-22 2011-06-30 Takeda Pharmaceutical The use of thieno(2,3-d)pyrimidine-2,4-dione derivatives which are gonadotropin releasing hormone (GnRH) antagonists as premature ovulation preventive agent
ES2534573T3 (es) 2007-04-06 2015-04-24 Neurocrine Biosciences, Inc. Antagonistas del receptor de la hormona liberadora de gonadotropina y métodos relacionados con los mismos
US8765948B2 (en) 2007-11-07 2014-07-01 Neurocrine Biosciences, Inc. Processes for the preparation of uracil derivatives
JOP20090061B1 (ar) 2008-02-11 2021-08-17 Ferring Int Center Sa طريقة معالجة سرطان البروستاتا بمضادات الهرمونات التناسلية GnRH
EP2329823A4 (en) 2008-09-03 2013-04-03 Takeda Pharmaceutical PROCESS FOR INCREASING THE ABSORPTION ABILITY OF A PREPARATION AND PREPARATION WITH INCREASED ABSORPTION ABILITY
HRP20190729T1 (hr) 2012-09-28 2019-06-14 Takeda Pharmaceutical Company Limited Metoda proizvodnje derivata tienopirimidina
US10821152B2 (en) 2014-08-26 2020-11-03 Betanien Hospital Methods, agents and compositions for treatment of inflammatory conditions
ES2988678T3 (es) 2015-02-26 2024-11-21 Takeda Pharmaceuticals Co Un comprimido que comprende un derivado de metoxiurea y partículas de manitol
CA3002791A1 (en) 2015-09-01 2017-03-09 Abbvie Inc. Methods of administering elagolix
US20180044977A1 (en) 2016-08-12 2018-02-15 Raynor Mfg. Co. Rolling door construction for controlling air leakage
EP3518932B1 (en) 2016-09-30 2024-11-13 Sumitomo Pharma Switzerland GmbH Treatment of prostate cancer
WO2018060501A2 (en) 2016-09-30 2018-04-05 Myovant Sciences Gmbh Methods of treating uterine fibroids and endometriosis

Also Published As

Publication number Publication date
IL265697B1 (en) 2023-03-01
US20190224196A1 (en) 2019-07-25
EP4520398A3 (en) 2025-04-02
US12097198B2 (en) 2024-09-24
AU2023201047A1 (en) 2023-03-23
WO2018060463A2 (en) 2018-04-05
US20210205303A1 (en) 2021-07-08
AU2017334035B2 (en) 2022-11-24
US12336990B2 (en) 2025-06-24
AU2017334035A1 (en) 2019-05-16
AU2023201047B2 (en) 2025-04-03
FI3518932T3 (fi) 2025-02-03
EP3518932B1 (en) 2024-11-13
US20240358700A1 (en) 2024-10-31
US20220401443A1 (en) 2022-12-22
NZ752918A (en) 2022-09-30
US20200129507A1 (en) 2020-04-30
CN110248661A (zh) 2019-09-17
PT3518932T (pt) 2025-01-16
IL308528A (en) 2024-01-01
IL300071A (en) 2023-03-01
IL265697A (en) 2019-05-30
SI3518932T1 (sl) 2025-03-31
US10449191B2 (en) 2019-10-22
BR112019006228A2 (pt) 2019-06-18
US12144809B1 (en) 2024-11-19
LT3518932T (lt) 2025-02-10
HRP20241740T1 (hr) 2025-02-28
JP7062673B2 (ja) 2022-05-06
CA3038875A1 (en) 2018-04-05
MX2019003733A (es) 2019-09-26
EP4520398A2 (en) 2025-03-12
US10786501B2 (en) 2020-09-29
HUE070578T2 (hu) 2025-06-28
EP3518932A2 (en) 2019-08-07
IL265697B2 (en) 2023-07-01
US20250082632A1 (en) 2025-03-13
JP2019529574A (ja) 2019-10-17
PL3518932T3 (pl) 2025-04-07
US11583526B2 (en) 2023-02-21
MX2023001468A (es) 2023-03-03
MA46361A (fr) 2021-03-31
US20250057839A1 (en) 2025-02-20
WO2018060463A3 (en) 2018-05-11
ES3002857T3 (en) 2025-03-07
US20250332166A1 (en) 2025-10-30

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