HUE070578T2 - Prosztatarák kezelése - Google Patents

Prosztatarák kezelése

Info

Publication number
HUE070578T2
HUE070578T2 HUE17823017A HUE17823017A HUE070578T2 HU E070578 T2 HUE070578 T2 HU E070578T2 HU E17823017 A HUE17823017 A HU E17823017A HU E17823017 A HUE17823017 A HU E17823017A HU E070578 T2 HUE070578 T2 HU E070578T2
Authority
HU
Hungary
Prior art keywords
prostate cancer
cancer treatment
treatment
prostate
cancer
Prior art date
Application number
HUE17823017A
Other languages
English (en)
Hungarian (hu)
Inventor
Vijaykumar Reddy Rajasekhar
Brendan Mark Johnson
David B Maclean
Lynn Seely
Paul Mudd
Helene M Faessel
Original Assignee
Sumitomo Pharma Switzerland Gmbh
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60915459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE070578(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Pharma Switzerland Gmbh, Takeda Pharmaceuticals Co filed Critical Sumitomo Pharma Switzerland Gmbh
Publication of HUE070578T2 publication Critical patent/HUE070578T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HUE17823017A 2016-09-30 2017-09-29 Prosztatarák kezelése HUE070578T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662402150P 2016-09-30 2016-09-30
US201662402004P 2016-09-30 2016-09-30

Publications (1)

Publication Number Publication Date
HUE070578T2 true HUE070578T2 (hu) 2025-06-28

Family

ID=60915459

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE17823017A HUE070578T2 (hu) 2016-09-30 2017-09-29 Prosztatarák kezelése

Country Status (21)

Country Link
US (8) US10449191B2 (enExample)
EP (2) EP4520398A3 (enExample)
JP (1) JP7062673B2 (enExample)
CN (1) CN110248661A (enExample)
AU (2) AU2017334035B2 (enExample)
BR (1) BR112019006228A2 (enExample)
CA (1) CA3038875A1 (enExample)
DK (1) DK3518932T3 (enExample)
ES (1) ES3002857T3 (enExample)
FI (1) FI3518932T3 (enExample)
HR (1) HRP20241740T1 (enExample)
HU (1) HUE070578T2 (enExample)
IL (3) IL300071A (enExample)
LT (1) LT3518932T (enExample)
MA (1) MA46361A (enExample)
MX (2) MX2019003733A (enExample)
NZ (1) NZ752918A (enExample)
PL (1) PL3518932T3 (enExample)
PT (1) PT3518932T (enExample)
SI (1) SI3518932T1 (enExample)
WO (1) WO2018060463A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMT202200255T1 (it) 2012-09-28 2022-07-21 Takeda Pharmaceuticals Co Forma cristallina di 1-(4-1-(2,6-difluorobenzil)-5-dimetilamminometil-3-(6-metossipiridazin-3-il)-2,4-diosso-1,2,3,4-tetraidrotieno(2,3-d)-pirimidin-6il)fenil)-3-metossiurea
SI3518932T1 (sl) 2016-09-30 2025-03-31 Takeda Pharmaceutical Company Limited Zdravljenje raka prostate
WO2018060501A2 (en) 2016-09-30 2018-04-05 Myovant Sciences Gmbh Methods of treating uterine fibroids and endometriosis
CN110194776B (zh) * 2019-06-27 2021-05-28 四川伊诺达博医药科技有限公司 一种瑞卢戈利的合成方法
JP2022551316A (ja) 2019-10-10 2022-12-08 ミオバント サイエンシズ ゲーエムベーハー N-(4-(1-(2,6-ジフルオロベンジル)-5-((ジメチルアミノ)メチル)-3-(6-メトキシ-3-ピリダジニル)-2,4-ジオキソ-1,2,3,4-テトラヒドロチエノ[2,3-d]ピリミジン-6-イル)フェニル)-N’-メトキシ尿素の結晶形
WO2021069700A1 (en) * 2019-10-10 2021-04-15 Myovant Sciences Gmbh Crystalline solvated forms of n-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4- tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
BR112022023937A2 (pt) 2020-05-29 2022-12-27 Myovant Sciences Gmbh Formas de dosagem oral sólidas de combinação de antagonistas do hormônio liberador de gonadotropina
US20230384316A1 (en) * 2020-10-20 2023-11-30 Baylor College Of Medicine Multiplex metabolic markers in plasma for early detection of african american prostate cancer
WO2022101303A1 (en) 2020-11-11 2022-05-19 Myovant Sciences Gmbh Methods of administering relugolix
WO2023066941A1 (en) 2021-10-18 2023-04-27 Myovant Sciences Gmbh Crystalline form of an ethanol solvate of n-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
WO2023152611A1 (en) * 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2710637B1 (fr) 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
TWI225863B (en) 1999-03-24 2005-01-01 Takeda Chemical Industries Ltd Thienopyrimidine compounds, their production and use
RU2233284C2 (ru) 1999-03-24 2004-07-27 Такеда Кемикал Индастриз, Лтд. Тиенопиримидиновые производные, способ их получения, фармацевтическая композиция и способ антагонизации гонадотропин-рилизинг гормона
US6849738B2 (en) 2000-02-29 2005-02-01 Takeda Chemical Industries, Ltd. Processes for the production of thienopyrimidine derivatives
WO2002024230A1 (en) 2000-09-22 2002-03-28 Takeda Chemical Industries, Ltd. Solid preparations
WO2003057689A1 (en) 2002-01-02 2003-07-17 Fujisawa Pharmaceutical Co., Ltd. Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them
EP1479684A4 (en) 2002-01-30 2006-01-04 Takeda Pharmaceutical THIENOPYRIMIDINES, METHODS OF MAKING AND USING SAME
CN1326569C (zh) 2002-02-26 2007-07-18 阿斯特拉曾尼卡有限公司 含有水溶性纤维素衍生物的iressa药物制剂
CN101153042A (zh) 2003-01-29 2008-04-02 武田药品工业株式会社 噻吩并嘧啶化合物及其用途
EP1646389B1 (en) 2003-07-07 2008-09-10 Neurocrine Biosciences, Inc. Pyrimidine-2,4-dione derivatives as gonadotropin-releasing hormone receptor antagonists
KR20080041662A (ko) 2005-07-22 2008-05-13 다케다 야쿠힌 고교 가부시키가이샤 조기 배란 예방제
MX2009010828A (es) 2007-04-06 2009-10-29 Neurocrine Biosciences Inc Antagonistas del receptor de la hormona liberadora de gonadotropina y metodos relacionados con los mismos.
US8765948B2 (en) 2007-11-07 2014-07-01 Neurocrine Biosciences, Inc. Processes for the preparation of uracil derivatives
TWI442932B (zh) 2008-02-11 2014-07-01 Ferring Int Ct Sa 以GnRH拮抗劑治療攝護腺癌的方法
US20110172249A1 (en) 2008-09-03 2011-07-14 Takeda Pharmaceutical Company Limted Method for improving absorbability of preparation, and preparation having improved absorbability
SMT202200255T1 (it) 2012-09-28 2022-07-21 Takeda Pharmaceuticals Co Forma cristallina di 1-(4-1-(2,6-difluorobenzil)-5-dimetilamminometil-3-(6-metossipiridazin-3-il)-2,4-diosso-1,2,3,4-tetraidrotieno(2,3-d)-pirimidin-6il)fenil)-3-metossiurea
AU2015308987B2 (en) 2014-08-26 2021-02-18 Kaass Discovery As Methods, agents and compositions for treatment of inflammatory conditions
TWI744224B (zh) 2015-02-26 2021-11-01 日商武田藥品工業股份有限公司 固形製劑
WO2017040841A1 (en) 2015-09-01 2017-03-09 Abbvie Inc. Methods of administering elagolix
US20180044977A1 (en) 2016-08-12 2018-02-15 Raynor Mfg. Co. Rolling door construction for controlling air leakage
WO2018060501A2 (en) 2016-09-30 2018-04-05 Myovant Sciences Gmbh Methods of treating uterine fibroids and endometriosis
SI3518932T1 (sl) 2016-09-30 2025-03-31 Takeda Pharmaceutical Company Limited Zdravljenje raka prostate
CN115626933A (zh) 2022-10-20 2023-01-20 上海医药工业研究院有限公司 一种瑞卢戈利盐溶剂合物、其制备方法和应用
CN115504994A (zh) 2022-10-20 2022-12-23 上海医药工业研究院有限公司 一种瑞卢戈利盐的晶型、其制备方法和应用

Also Published As

Publication number Publication date
HRP20241740T1 (hr) 2025-02-28
CN110248661A (zh) 2019-09-17
ES3002857T3 (en) 2025-03-07
IL265697B1 (en) 2023-03-01
FI3518932T3 (fi) 2025-02-03
PT3518932T (pt) 2025-01-16
AU2023201047B2 (en) 2025-04-03
US12336990B2 (en) 2025-06-24
AU2023201047A1 (en) 2023-03-23
US20210205303A1 (en) 2021-07-08
US20220401443A1 (en) 2022-12-22
BR112019006228A2 (pt) 2019-06-18
CA3038875A1 (en) 2018-04-05
SI3518932T1 (sl) 2025-03-31
US20250057839A1 (en) 2025-02-20
US20250332166A1 (en) 2025-10-30
US20250082632A1 (en) 2025-03-13
WO2018060463A3 (en) 2018-05-11
MX2019003733A (es) 2019-09-26
AU2017334035B2 (en) 2022-11-24
IL300071A (en) 2023-03-01
PL3518932T3 (pl) 2025-04-07
EP3518932B1 (en) 2024-11-13
IL265697B2 (en) 2023-07-01
US12629370B2 (en) 2026-05-19
AU2017334035A1 (en) 2019-05-16
JP7062673B2 (ja) 2022-05-06
US10786501B2 (en) 2020-09-29
EP4520398A3 (en) 2025-04-02
LT3518932T (lt) 2025-02-10
US20240358700A1 (en) 2024-10-31
US12097198B2 (en) 2024-09-24
NZ752918A (en) 2022-09-30
US10449191B2 (en) 2019-10-22
US11583526B2 (en) 2023-02-21
US20200129507A1 (en) 2020-04-30
US12144809B1 (en) 2024-11-19
DK3518932T3 (da) 2025-01-27
JP2019529574A (ja) 2019-10-17
US20190224196A1 (en) 2019-07-25
IL265697A (en) 2019-05-30
MA46361A (fr) 2021-03-31
WO2018060463A2 (en) 2018-04-05
MX2023001468A (es) 2023-03-03
EP4520398A2 (en) 2025-03-12
EP3518932A2 (en) 2019-08-07
IL308528A (en) 2024-01-01

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