AU2017207359C1 - Method of treating C3 glomerulopathy - Google Patents

Method of treating C3 glomerulopathy Download PDF

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Publication number
AU2017207359C1
AU2017207359C1 AU2017207359A AU2017207359A AU2017207359C1 AU 2017207359 C1 AU2017207359 C1 AU 2017207359C1 AU 2017207359 A AU2017207359 A AU 2017207359A AU 2017207359 A AU2017207359 A AU 2017207359A AU 2017207359 C1 AU2017207359 C1 AU 2017207359C1
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Australia
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compound
human
glomerulopathy
group
complement
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AU2017207359A
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AU2017207359B2 (en
AU2017207359A1 (en
Inventor
Petrus BEKKER
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Chemocentryx Inc
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Chemocentryx Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
AU2017207359A 2016-01-14 2017-01-12 Method of treating C3 glomerulopathy Active AU2017207359C1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662278788P 2016-01-14 2016-01-14
US62/278,788 2016-01-14
US201662280346P 2016-01-19 2016-01-19
US62/280,346 2016-01-19
US201662347450P 2016-06-08 2016-06-08
US62/347,450 2016-06-08
US201662397527P 2016-09-21 2016-09-21
US62/397,527 2016-09-21
PCT/US2017/013132 WO2017123716A1 (en) 2016-01-14 2017-01-12 Method of treating c3 glomerulopathy

Publications (3)

Publication Number Publication Date
AU2017207359A1 AU2017207359A1 (en) 2018-07-26
AU2017207359B2 AU2017207359B2 (en) 2022-04-14
AU2017207359C1 true AU2017207359C1 (en) 2022-09-01

Family

ID=59312069

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017207359A Active AU2017207359C1 (en) 2016-01-14 2017-01-12 Method of treating C3 glomerulopathy

Country Status (18)

Country Link
US (3) US20170202821A1 (https=)
EP (1) EP3402486B1 (https=)
JP (4) JP7339733B2 (https=)
KR (1) KR102767008B1 (https=)
CN (1) CN108601790B (https=)
AU (1) AU2017207359C1 (https=)
BR (2) BR122024002810A2 (https=)
CA (1) CA3010735C (https=)
ES (1) ES3026359T3 (https=)
IL (1) IL260539B (https=)
MA (1) MA43872A (https=)
MX (2) MX2022006069A (https=)
NZ (1) NZ744083A (https=)
RU (1) RU2742888C2 (https=)
SG (1) SG11201805828YA (https=)
TW (1) TWI791423B (https=)
WO (1) WO2017123716A1 (https=)
ZA (1) ZA201804513B (https=)

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WO2017035405A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Amino compounds for treatment of immune and inflammatory disorders
WO2017035401A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Amide compounds for treatment of immune and inflammatory disorders
CN108601790B (zh) 2016-01-14 2026-01-27 凯莫森特里克斯股份有限公司 C3肾小球病的治疗方法
WO2018160891A1 (en) 2017-03-01 2018-09-07 Achillion Pharmaceutical, Inc. Pharmaceutical compounds for treatment of medical disorders
CN110603252A (zh) 2017-03-01 2019-12-20 艾其林医药公司 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
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US20210215714A1 (en) * 2018-05-25 2021-07-15 Achillion Pharmaceuticals, Inc. Complement alternative pathway-associated nephropathy biomarkers
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MX2023001504A (es) * 2020-08-07 2023-04-27 Kira Pharmaceuticals Suzhou Ltd Compuestos como inhibidores del receptor del componente complemento 5a (c5ar).
EP4262800A4 (en) * 2020-12-21 2024-11-20 ChemoCentryx, Inc. TREATMENT OF C3 GLOMERULOPATHY WITH A C5A INHIBITOR
CN115192563B (zh) * 2022-05-09 2023-10-13 北京大学第一医院 C3a/C3aR通路拮抗剂治疗原发性膜性肾病的用途

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Also Published As

Publication number Publication date
CN108601790B (zh) 2026-01-27
MX2018008624A (es) 2018-12-10
US11285138B2 (en) 2022-03-29
BR112018014222A2 (pt) 2018-12-11
CA3010735A1 (en) 2017-07-20
IL260539B (en) 2021-05-31
AU2017207359B2 (en) 2022-04-14
JP7788814B2 (ja) 2025-12-19
SG11201805828YA (en) 2018-08-30
EP3402486C0 (en) 2025-03-19
JP2021183625A (ja) 2021-12-02
ES3026359T3 (en) 2025-06-11
TW201726134A (zh) 2017-08-01
JP7339733B2 (ja) 2023-09-06
JP2023126235A (ja) 2023-09-07
RU2018129378A (ru) 2020-02-14
US11779576B2 (en) 2023-10-10
JP2024110998A (ja) 2024-08-16
CN108601790A (zh) 2018-09-28
ZA201804513B (en) 2024-01-31
KR102767008B1 (ko) 2025-02-11
CA3010735C (en) 2023-06-13
TWI791423B (zh) 2023-02-11
KR20180102642A (ko) 2018-09-17
RU2018129378A3 (https=) 2020-05-20
US20220354837A1 (en) 2022-11-10
RU2742888C2 (ru) 2021-02-11
US20190201388A1 (en) 2019-07-04
EP3402486B1 (en) 2025-03-19
EP3402486A4 (en) 2019-08-28
NZ744083A (en) 2022-07-01
WO2017123716A1 (en) 2017-07-20
JP2019501935A (ja) 2019-01-24
BR122024002810A2 (pt) 2024-03-12
AU2017207359A1 (en) 2018-07-26
EP3402486A1 (en) 2018-11-21
MX2022006069A (es) 2023-01-12
MA43872A (fr) 2021-05-19
US20170202821A1 (en) 2017-07-20

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