AU2016286112B2 - Optimally activated dendritic cells that induce an improved or increased anti-tumor immune response - Google Patents

Optimally activated dendritic cells that induce an improved or increased anti-tumor immune response Download PDF

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AU2016286112B2
AU2016286112B2 AU2016286112A AU2016286112A AU2016286112B2 AU 2016286112 B2 AU2016286112 B2 AU 2016286112B2 AU 2016286112 A AU2016286112 A AU 2016286112A AU 2016286112 A AU2016286112 A AU 2016286112A AU 2016286112 B2 AU2016286112 B2 AU 2016286112B2
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cells
dendritic cells
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AU2016286112A1 (en
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Marnix L. Bosch
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Northwest Biotherapeutics LLC
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • C12N5/064—Immunosuppressive dendritic cells
    • A—HUMAN NECESSITIES
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    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61K40/19—Dendritic cells
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    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
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    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/35—Cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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AU2016286112A 2015-06-30 2016-06-29 Optimally activated dendritic cells that induce an improved or increased anti-tumor immune response Active AU2016286112B2 (en)

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AU2023202977A AU2023202977B2 (en) 2015-06-30 2023-05-12 Optimally activated dendritic cells that induce an improved or increased anti-tumor immune response

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US201562187086P 2015-06-30 2015-06-30
US62/187,086 2015-06-30
PCT/US2016/040134 WO2017004230A1 (en) 2015-06-30 2016-06-29 Optimally activated dendritic cells that induce an improved or increased anti-tumor immune response

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US (2) US11124768B2 (https=)
EP (2) EP3317403B1 (https=)
JP (3) JP6985939B2 (https=)
KR (1) KR102763373B1 (https=)
CN (2) CN107849537A (https=)
AR (1) AR106496A1 (https=)
AU (2) AU2016286112B2 (https=)
CA (1) CA2990640A1 (https=)
ES (1) ES3032055T3 (https=)
IL (2) IL312668A (https=)
MX (2) MX2018000056A (https=)
PL (1) PL424035A1 (https=)
RU (1) RU2018103235A (https=)
WO (1) WO2017004230A1 (https=)

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WO2018160666A1 (en) * 2017-02-28 2018-09-07 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Short-term activated dc1s and methods for their production and use
SG11202011806WA (en) 2018-06-21 2021-01-28 Univ Gent Method for the in vitro differentiation and maturation of dendritic cells for therapeutic use
AU2020363707A1 (en) * 2019-10-07 2022-04-28 Northwest Biotherapeutics, Inc. In vitro methods and compositions for enhancing the activation of dendritic cells and t cells, and for inducing a th-1 immune response
CN117417886B (zh) * 2023-10-20 2024-05-14 广东壹加再生医学研究院有限公司 一种负载肿瘤抗原的树突状细胞激活的t淋巴细胞的培养方法
CN119286782B (zh) * 2024-12-11 2025-04-04 上海赛笠百傲生物医药有限公司 一种高效诱导外周血来源单核细胞至不成熟树突状细胞的方法

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KR100887560B1 (ko) 2007-04-24 2009-03-09 크레아젠 주식회사 준성숙 수지상 세포를 포함하는 류마티스 관절염 치료용약제학적 조성물
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JP2022023248A (ja) 2022-02-07
CN114774356A (zh) 2022-07-22
MX2018000056A (es) 2018-05-28
BR112017028602A2 (pt) 2018-09-04
JP6985939B2 (ja) 2021-12-22
EP3317403A1 (en) 2018-05-09
RU2018103235A (ru) 2019-07-31
CN107849537A (zh) 2018-03-27
US20180187145A1 (en) 2018-07-05
CA2990640A1 (en) 2017-01-05
IL256522A (en) 2018-02-28
US11124768B2 (en) 2021-09-21
EP3317403A4 (en) 2019-07-03
JP2024101059A (ja) 2024-07-26
HK1255084A1 (en) 2019-08-02
AU2023202977A1 (en) 2023-06-01
US20220145246A1 (en) 2022-05-12
JP2018523996A (ja) 2018-08-30
AU2023202977B2 (en) 2026-03-05
WO2017004230A1 (en) 2017-01-05
AU2016286112A1 (en) 2018-02-15
KR102763373B1 (ko) 2025-02-07
KR20180022949A (ko) 2018-03-06
IL312668A (en) 2024-07-01
AR106496A1 (es) 2018-01-24
EP4574159A3 (en) 2025-09-17
IL256522B2 (en) 2024-10-01
EP3317403B1 (en) 2025-03-05
IL256522B1 (en) 2024-06-01
PL424035A1 (pl) 2019-01-02
ES3032055T3 (en) 2025-07-15
MX2023001622A (es) 2023-03-09
EP4574159A2 (en) 2025-06-25
RU2018103235A3 (https=) 2019-12-23

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