AU2014331841B2 - Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease - Google Patents
Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease Download PDFInfo
- Publication number
- AU2014331841B2 AU2014331841B2 AU2014331841A AU2014331841A AU2014331841B2 AU 2014331841 B2 AU2014331841 B2 AU 2014331841B2 AU 2014331841 A AU2014331841 A AU 2014331841A AU 2014331841 A AU2014331841 A AU 2014331841A AU 2014331841 B2 AU2014331841 B2 AU 2014331841B2
- Authority
- AU
- Australia
- Prior art keywords
- antibodies
- ibs
- vinculin
- level
- cdt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Ecology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2020203468A AU2020203468A1 (en) | 2013-10-09 | 2020-05-27 | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361888658P | 2013-10-09 | 2013-10-09 | |
| US61/888,658 | 2013-10-09 | ||
| PCT/US2014/059957 WO2015054529A1 (en) | 2013-10-09 | 2014-10-09 | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020203468A Division AU2020203468A1 (en) | 2013-10-09 | 2020-05-27 | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2014331841A1 AU2014331841A1 (en) | 2016-03-24 |
| AU2014331841B2 true AU2014331841B2 (en) | 2020-03-12 |
Family
ID=52813648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014331841A Active AU2014331841B2 (en) | 2013-10-09 | 2014-10-09 | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
| AU2020203468A Abandoned AU2020203468A1 (en) | 2013-10-09 | 2020-05-27 | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020203468A Abandoned AU2020203468A1 (en) | 2013-10-09 | 2020-05-27 | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9851361B2 (enExample) |
| EP (1) | EP3054977B1 (enExample) |
| JP (1) | JP6567509B2 (enExample) |
| KR (1) | KR102259588B1 (enExample) |
| CN (1) | CN105744956B (enExample) |
| AU (2) | AU2014331841B2 (enExample) |
| BR (1) | BR112016007474A2 (enExample) |
| CA (1) | CA2923651C (enExample) |
| CL (1) | CL2016000820A1 (enExample) |
| ES (1) | ES2892905T3 (enExample) |
| IL (1) | IL244971B2 (enExample) |
| MX (1) | MX383423B (enExample) |
| NZ (1) | NZ717633A (enExample) |
| PE (1) | PE20160882A1 (enExample) |
| PL (1) | PL3054977T3 (enExample) |
| PT (1) | PT3054977T (enExample) |
| RU (1) | RU2683781C2 (enExample) |
| SG (1) | SG11201601733VA (enExample) |
| WO (1) | WO2015054529A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010213708B2 (en) | 2009-02-11 | 2015-12-10 | Cedars-Sinai Medical Center | Antibody to cytolethal distending toxin of Campylobacter jejuni |
| US11693009B2 (en) | 2009-02-11 | 2023-07-04 | Cedars-Sinai Medical Center | Methods for detecting post-infectious irritable bowel syndrome |
| MX383428B (es) | 2012-09-17 | 2025-03-13 | Cedars Sinai Medical Center | Determinaciòn de trastornos de la motilidad de los intestinos y la vejiga, y de la fibromialgia. |
| KR102259588B1 (ko) | 2013-10-09 | 2021-06-02 | 세다르스-신나이 메디칼 센터 | 과민성 장 증후군 및 염증성 장 질환의 진단 및 치료 |
| MX384921B (es) | 2014-10-09 | 2025-03-14 | Cedars Sinai Medical Center | Métodos y sistemas para distinguir el síndrome del intestino irritable de la enfermedad inflamatoria intestinal y la enfermedad celíaca. |
| CN105784989A (zh) * | 2016-05-17 | 2016-07-20 | 上海凯璟生物科技有限公司 | 一种肠易激综合症标志物CdtB抗体检测试剂盒及其制备方法 |
| CN106053827A (zh) * | 2016-05-17 | 2016-10-26 | 上海凯璟生物科技有限公司 | 一种肠易激综合症标志物Vinculin抗体检测试剂盒及其制备方法 |
| US11549146B2 (en) | 2016-05-20 | 2023-01-10 | Cedars-Sinai Medical Center | Diagnosis of inflammatory bowel disease based on genes |
| EP3573650A4 (en) | 2017-01-30 | 2020-12-09 | Cedars-Sinai Medical Center | DIAGNOSIS OF SCLERODERMIA |
| RU2763258C1 (ru) * | 2020-07-13 | 2021-12-28 | Евгения Николаевна Воронина | Способ дифференциальной диагностики воспалительных заболеваний кишечника у детей по комплексу клинико-анамнестических, лабораторных и инструментальных критериев |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014042828A2 (en) * | 2012-09-17 | 2014-03-20 | Cedars-Sinai Medical Center | Diagnosis and treatment of motility disorders of the gut and bladder, and of fibromyalgia |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5691151A (en) * | 1994-10-07 | 1997-11-25 | Regents Of University Of California | Methods of screening for ulcerative colitis and crohn's disease by detecting VH3-15 autoantibody and panca |
| US6562629B1 (en) | 1999-08-11 | 2003-05-13 | Cedars-Sinai Medical Center | Method of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth by detecting the presence of anti-saccharomyces cerivisiae antibodies (asca) in human serum |
| US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| FR2806805A1 (fr) | 2000-03-22 | 2001-09-28 | Centre Nat Rech Scient | SEQUENCE PEPTIDIQUES COMPRENANT UN OU PLUSIEURS MOTIFS DE LIAISON AUX PROTEINES DE LA FAMILLE Ena/VASP, ET LEURS UTILISATIONS |
| US20040018528A1 (en) | 2002-05-17 | 2004-01-29 | Sugen, Inc. | Novel biomarkers of tyrosine kinase inhibitor exposure and activity in mammals |
| AU2003291625B2 (en) | 2002-09-16 | 2009-10-08 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US7595386B2 (en) | 2003-01-24 | 2009-09-29 | William Beaumont Hospital | Methods and compositions for heat activated gene therapy using cytolethal distending toxin |
| EP1617846A1 (en) * | 2003-04-08 | 2006-01-25 | Progenics Pharmaceuticals, Inc. | The use of peripheral opiois antagonists, especially methylnaltrexone to treat irritable bowel syndrome |
| EP2280285A1 (en) * | 2003-09-15 | 2011-02-02 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate inflammatory and autoimmune diseases |
| ES2456710T3 (es) | 2003-12-05 | 2014-04-23 | Fuso Pharmaceutical Industries Ltd. | Genes de toxinas de distensión citoletales como dianas para la detección de bacterias Campylobacter |
| EP2102367A2 (en) | 2006-11-09 | 2009-09-23 | XDX, Inc. | Methods for diagnosing and monitoring the status of systemic lupus erythematosus |
| JP2011507509A (ja) | 2007-12-20 | 2011-03-10 | インデックス・ダイアグノスティックス・エイビイ | Ｉｂｄとｉｂｓとの区別、ｉｂｄの疾患タイプ間の更なる識別における使用する方法およびキット |
| WO2010060098A1 (en) | 2008-11-24 | 2010-05-27 | Cedars-Sinai Medical Center | Antioxidant camptothecin derivatives and antioxidant antineoplastic nanospheres thereof |
| AU2010213708B2 (en) | 2009-02-11 | 2015-12-10 | Cedars-Sinai Medical Center | Antibody to cytolethal distending toxin of Campylobacter jejuni |
| BRPI1008058A8 (pt) | 2009-02-11 | 2018-03-27 | Cedars Sinai Medical Center | uso de antibióticos para reduzir a probabilidade de desenvolver síndrome do intestino irritável pós-infecciosa |
| FR2942541A1 (fr) | 2009-02-25 | 2010-08-27 | Assist Publ Hopitaux De Paris | Procede de diagnostic d'une vascularite |
| RU2397178C1 (ru) * | 2009-02-27 | 2010-08-20 | Федеральное государственное учреждение науки "Центральный научно-исследовательский институт эпидемиологии" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Диагностическая тест-система в формате иммуночипа и способ серологической дифференциальной диагностики сифилиса |
| IT1400989B1 (it) | 2010-07-13 | 2013-07-05 | Segix Italia S R L Ora Istituto Biochimico Naz Savio S R L | Forme di somministrazione orale a rilascio controllato di rifampicina per il trattamento di infezioni batteriche dell' apparato intestinale. |
| GB201017520D0 (en) | 2010-10-15 | 2010-12-01 | Sense Proteomic Ltd | Biomarkers |
| KR102259588B1 (ko) | 2013-10-09 | 2021-06-02 | 세다르스-신나이 메디칼 센터 | 과민성 장 증후군 및 염증성 장 질환의 진단 및 치료 |
| MX384921B (es) | 2014-10-09 | 2025-03-14 | Cedars Sinai Medical Center | Métodos y sistemas para distinguir el síndrome del intestino irritable de la enfermedad inflamatoria intestinal y la enfermedad celíaca. |
| CN106091069A (zh) | 2016-06-15 | 2016-11-09 | 安徽省绿巨人环境技术有限公司 | 一种废水再利用装置 |
| EP3573650A4 (en) | 2017-01-30 | 2020-12-09 | Cedars-Sinai Medical Center | DIAGNOSIS OF SCLERODERMIA |
-
2014
- 2014-10-09 KR KR1020167011774A patent/KR102259588B1/ko active Active
- 2014-10-09 RU RU2016116766A patent/RU2683781C2/ru active
- 2014-10-09 AU AU2014331841A patent/AU2014331841B2/en active Active
- 2014-10-09 SG SG11201601733VA patent/SG11201601733VA/en unknown
- 2014-10-09 JP JP2016521777A patent/JP6567509B2/ja active Active
- 2014-10-09 NZ NZ717633A patent/NZ717633A/en unknown
- 2014-10-09 IL IL244971A patent/IL244971B2/en unknown
- 2014-10-09 ES ES14851688T patent/ES2892905T3/es active Active
- 2014-10-09 WO PCT/US2014/059957 patent/WO2015054529A1/en not_active Ceased
- 2014-10-09 PT PT14851688T patent/PT3054977T/pt unknown
- 2014-10-09 PL PL14851688T patent/PL3054977T3/pl unknown
- 2014-10-09 EP EP14851688.3A patent/EP3054977B1/en active Active
- 2014-10-09 US US15/021,850 patent/US9851361B2/en active Active
- 2014-10-09 CA CA2923651A patent/CA2923651C/en active Active
- 2014-10-09 CN CN201480055994.5A patent/CN105744956B/zh active Active
- 2014-10-09 BR BR112016007474A patent/BR112016007474A2/pt not_active Application Discontinuation
- 2014-10-09 PE PE2016000430A patent/PE20160882A1/es unknown
- 2014-10-09 MX MX2016004167A patent/MX383423B/es unknown
-
2016
- 2016-04-08 CL CL2016000820A patent/CL2016000820A1/es unknown
-
2017
- 2017-12-12 US US15/839,366 patent/US10352944B2/en active Active
-
2020
- 2020-05-27 AU AU2020203468A patent/AU2020203468A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014042828A2 (en) * | 2012-09-17 | 2014-03-20 | Cedars-Sinai Medical Center | Diagnosis and treatment of motility disorders of the gut and bladder, and of fibromyalgia |
Non-Patent Citations (1)
| Title |
|---|
| MORALES W. ET AL., "Antibodies to cytolethal distending toxin B and auto-antibodies to human vinculin are elevated in IBS subjects", GASTROENTEROL., (2013), vol. 144, no. 5, page S-914 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |