AU2014331652B2 - Compositions for modulating C9ORF72 expression - Google Patents

Compositions for modulating C9ORF72 expression Download PDF

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Publication number
AU2014331652B2
AU2014331652B2 AU2014331652A AU2014331652A AU2014331652B2 AU 2014331652 B2 AU2014331652 B2 AU 2014331652B2 AU 2014331652 A AU2014331652 A AU 2014331652A AU 2014331652 A AU2014331652 A AU 2014331652A AU 2014331652 B2 AU2014331652 B2 AU 2014331652B2
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certain embodiments
compound
c9orf72
modified
modified oligonucleotide
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AU2014331652A1 (en
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Susan M. Freier
Frank Rigo
Priyam SINGH
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Ionis Pharmaceuticals Inc
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Ionis Pharmaceuticals Inc
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
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    • C12N2310/34Spatial arrangement of the modifications
    • C12N2310/341Gapmers, i.e. of the type ===---===
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    • C12N2310/30Chemical structure
    • C12N2310/34Spatial arrangement of the modifications
    • C12N2310/343Spatial arrangement of the modifications having patterns, e.g. ==--==--==--

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AU2014331652A 2013-10-11 2014-10-11 Compositions for modulating C9ORF72 expression Ceased AU2014331652B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2020220099A AU2020220099A1 (en) 2013-10-11 2020-08-19 Compositions for modulating c9orf72 expression

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361890108P 2013-10-11 2013-10-11
US61/890,108 2013-10-11
US201361891313P 2013-10-15 2013-10-15
US61/891,313 2013-10-15
US201361919540P 2013-12-20 2013-12-20
US61/919,540 2013-12-20
US201461927903P 2014-01-15 2014-01-15
US61/927,903 2014-01-15
US201461980502P 2014-04-16 2014-04-16
US61/980,502 2014-04-16
PCT/US2014/060194 WO2015054676A2 (en) 2013-10-11 2014-10-11 Compositions for modulating c9orf72 expression

Related Child Applications (1)

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AU2020220099A Division AU2020220099A1 (en) 2013-10-11 2020-08-19 Compositions for modulating c9orf72 expression

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AU2014331652A1 AU2014331652A1 (en) 2016-04-21
AU2014331652B2 true AU2014331652B2 (en) 2020-05-21

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AU2020220099A Abandoned AU2020220099A1 (en) 2013-10-11 2020-08-19 Compositions for modulating c9orf72 expression

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US (3) US10221414B2 (https=)
EP (2) EP4166667A3 (https=)
JP (2) JP6679476B2 (https=)
KR (1) KR20160062069A (https=)
CN (2) CN112080502A (https=)
AU (2) AU2014331652B2 (https=)
BR (1) BR112016007751A2 (https=)
CA (1) CA2926408A1 (https=)
CL (3) CL2016000839A1 (https=)
IL (1) IL244759A0 (https=)
MX (2) MX2016004651A (https=)
MY (1) MY192689A (https=)
PH (1) PH12016500603A1 (https=)
RU (1) RU2748426C2 (https=)
SG (2) SG10201808903UA (https=)
WO (1) WO2015054676A2 (https=)

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