AU2014288857B2 - A pharmaceutical combination for the treatment of melanoma - Google Patents
A pharmaceutical combination for the treatment of melanoma Download PDFInfo
- Publication number
- AU2014288857B2 AU2014288857B2 AU2014288857A AU2014288857A AU2014288857B2 AU 2014288857 B2 AU2014288857 B2 AU 2014288857B2 AU 2014288857 A AU2014288857 A AU 2014288857A AU 2014288857 A AU2014288857 A AU 2014288857A AU 2014288857 B2 AU2014288857 B2 AU 2014288857B2
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- AU
- Australia
- Prior art keywords
- melanoma
- inhibitor
- compound
- braf
- vemurafenib
- Prior art date
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- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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| WO2016197129A1 (en) | 2015-06-05 | 2016-12-08 | The Board Of Trustees Of The University Of Illinois | Pac-1 combination therapy |
| CN108135854B (zh) * | 2015-06-30 | 2022-03-11 | 基因泰克公司 | 含有药物的立即释放片剂和用于形成片剂的方法 |
| JP6987084B2 (ja) * | 2016-03-16 | 2021-12-22 | ディセルナ ファーマシューティカルズ インコーポレイテッド | β−カテニン関連疾患又は障害の治療のための組成物及び方法 |
| AU2018209164B2 (en) | 2017-01-17 | 2021-11-04 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| CN110799245B (zh) * | 2017-05-16 | 2022-08-09 | 生物医学谷探索股份有限公司 | 用于治疗具有非典型braf突变的癌症的组合物和方法 |
| AU2018368453B2 (en) | 2017-11-17 | 2024-05-30 | The Board Of Trustees Of The University Of Illinois | Cancer therapy by degrading dual MEK signaling |
| CN107827726B (zh) * | 2017-11-28 | 2020-09-15 | 辽宁中医药大学 | 马齿苋中化合物Oleracone E及其提取分离方法 |
| CN108591464B (zh) * | 2018-06-28 | 2020-06-23 | 宁波奥克斯高科技有限公司 | 一种气体绝缘开关柜用密封结构 |
| KR20210084442A (ko) | 2018-10-05 | 2021-07-07 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 포도막 흑색종 치료를 위한 병용 요법 |
| EP3952861A4 (en) | 2019-04-11 | 2023-01-11 | MEI Pharma, Inc. | VORUCICLIB POLYMORPHS AND PROCESSES FOR THEIR PRODUCTION AND USE |
| US20240000789A1 (en) * | 2020-05-12 | 2024-01-04 | Novartis Ag | Therapeutic combinations comprising a craf inhibitor |
| CN112168821B (zh) * | 2020-11-09 | 2022-10-14 | 中南大学湘雅医院 | 一种治疗维罗非尼耐药的黑色素瘤的联合用药物及其应用 |
| CN117043159A (zh) * | 2020-11-19 | 2023-11-10 | 梅制药公司 | Kras突变型癌症的治疗 |
| JP2024500288A (ja) * | 2020-11-19 | 2024-01-09 | メイ ファーマ，インク． | Ｋｒａｓ変異癌の治療 |
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Patent Citations (1)
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|---|---|---|---|---|
| US20120321637A1 (en) * | 2011-06-20 | 2012-12-20 | The Board Of Regents Of The University Of Texas System | Combination cancer therapy with herv inhibition |
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