AU2014243704A1 - Methods and compositions for detecting pancreatic cancer - Google Patents

Methods and compositions for detecting pancreatic cancer Download PDF

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Publication number
AU2014243704A1
AU2014243704A1 AU2014243704A AU2014243704A AU2014243704A1 AU 2014243704 A1 AU2014243704 A1 AU 2014243704A1 AU 2014243704 A AU2014243704 A AU 2014243704A AU 2014243704 A AU2014243704 A AU 2014243704A AU 2014243704 A1 AU2014243704 A1 AU 2014243704A1
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AU
Australia
Prior art keywords
pancreatic cancer
protein
level
cancer biomarker
homo sapiens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2014243704A
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English (en)
Inventor
Lewis K. Pannell
Jana ROCKER
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Creatics LLC
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Creatics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creatics LLC filed Critical Creatics LLC
Publication of AU2014243704A1 publication Critical patent/AU2014243704A1/en
Priority to AU2020202066A priority Critical patent/AU2020202066B2/en
Priority to AU2022224782A priority patent/AU2022224782A1/en
Abandoned legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2014243704A 2013-03-13 2014-03-13 Methods and compositions for detecting pancreatic cancer Abandoned AU2014243704A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2020202066A AU2020202066B2 (en) 2013-03-13 2020-03-23 Methods and compositions for detecting pancreatic cancer
AU2022224782A AU2022224782A1 (en) 2013-03-13 2022-08-31 Methods and compositions for detecting pancreatic cancer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361780574P 2013-03-13 2013-03-13
US61/780,574 2013-03-13
PCT/US2014/026857 WO2014160499A2 (en) 2013-03-13 2014-03-13 Methods and compositions for detecting pancreatic cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2020202066A Division AU2020202066B2 (en) 2013-03-13 2020-03-23 Methods and compositions for detecting pancreatic cancer

Publications (1)

Publication Number Publication Date
AU2014243704A1 true AU2014243704A1 (en) 2015-09-10

Family

ID=50933479

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2014243704A Abandoned AU2014243704A1 (en) 2013-03-13 2014-03-13 Methods and compositions for detecting pancreatic cancer
AU2020202066A Ceased AU2020202066B2 (en) 2013-03-13 2020-03-23 Methods and compositions for detecting pancreatic cancer
AU2022224782A Abandoned AU2022224782A1 (en) 2013-03-13 2022-08-31 Methods and compositions for detecting pancreatic cancer

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2020202066A Ceased AU2020202066B2 (en) 2013-03-13 2020-03-23 Methods and compositions for detecting pancreatic cancer
AU2022224782A Abandoned AU2022224782A1 (en) 2013-03-13 2022-08-31 Methods and compositions for detecting pancreatic cancer

Country Status (7)

Country Link
US (3) US20160033511A1 (https=)
EP (1) EP2972375A2 (https=)
JP (3) JP6646571B2 (https=)
AU (3) AU2014243704A1 (https=)
CA (1) CA2902841A1 (https=)
HK (1) HK1214652A1 (https=)
WO (1) WO2014160499A2 (https=)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2347775T (pt) 2005-12-13 2020-07-14 The President And Fellows Of Harvard College Estruturas em andaime para transplante celular
CA2681899C (en) 2007-03-27 2018-06-19 Immunovia Ab Methods for diagnosis of pancreatic adenocarcinoma, and biomarkers and arrays for use in the same
JP6104806B2 (ja) 2010-10-06 2017-03-29 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 材料に基づく細胞治療のための注射可能孔形成性ハイドロゲル
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
HK1200037A1 (en) 2011-09-12 2015-07-31 克里蒂科斯有限责任公司 Non-invasive methods of detecting target molecules
WO2013152860A2 (en) * 2012-04-11 2013-10-17 Dutalys Gmbh Improved antibody light chains
CN104244929B (zh) 2012-04-16 2017-04-05 哈佛学院董事会 用于调节免疫反应的介孔二氧化硅组合物
NZ703411A (en) 2012-06-27 2017-09-29 Berg Llc Use of markers in the diagnosis and treatment of prostate cancer
BR112015023207A8 (pt) 2013-03-15 2018-01-23 Shire Viropharma Inc composições de ci-inh e métodos para prevenção e tratamento de desordens associadas à deficiência de inibidor de c1 esterase.
ES2702183T3 (es) 2013-03-15 2019-02-27 Mayo Found Medical Education & Res Identificación y monitorización de inmunoglobulinas monoclonales por masa molecular
JP6652916B2 (ja) * 2013-06-20 2020-02-26 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 膵臓がんを診断するための方法
WO2015154052A1 (en) 2014-04-04 2015-10-08 Mayo Foundation For Medical Education And Research Isotyping immunoglobulins using accurate molecular mass
JP7348708B2 (ja) 2014-04-30 2023-09-21 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 組み合わせワクチン装置および癌細胞を殺滅する方法
JP5974190B2 (ja) * 2014-05-26 2016-08-23 オリンパス株式会社 膵癌進行度を示すための方法
KR20160045547A (ko) * 2014-10-17 2016-04-27 에스케이텔레콤 주식회사 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단방법
SG10202012249YA (en) 2014-12-08 2021-01-28 Berg Llc Use of markers including filamin a in the diagnosis and treatment of prostate cancer
ES2871624T3 (es) 2014-12-19 2021-10-29 Hoffmann La Roche Transglutaminasas microbianas, sustratos para las mismas y procedimientos para el uso de las mismas
US11054425B2 (en) 2014-12-19 2021-07-06 Roche Sequencing Solutions, Inc. System and method for identification and characterization of transglutaminase species
CA2971246C (en) 2014-12-19 2020-07-14 F. Hoffmann-La Roche Ag Identification of transglutaminase substrates and uses therefor
HK1247861A1 (zh) 2015-01-30 2018-10-05 President And Fellows Of Harvard College 用於癌症治疗的肿瘤周围和肿瘤内部材料
US20160271120A1 (en) * 2015-03-17 2016-09-22 Oakdene Holdings Llc Pharmaceutical composition for cleansing of the gastrointestinal tract
GB201505654D0 (en) * 2015-04-01 2015-05-13 Nordic Bioscience As Immunoassay for collagen type VI sequence
WO2016164593A1 (en) * 2015-04-07 2016-10-13 President And Fellows Of Harvard College Compositions and methods for modulating hydroxylation of acc2 by phd3
WO2016164705A1 (en) 2015-04-10 2016-10-13 Omar Abdel-Rahman Ali Immune cell trapping devices and methods for making and using the same
WO2016169581A1 (en) * 2015-04-20 2016-10-27 Consejo Superior De Investigaciones Científicas Agents binding specifically to human cadherin-17, human cadherin-5, human cadherin-6 and human cadherin-20 rgd motif
HK1254866A1 (zh) 2015-06-25 2019-07-26 Immatics Biotechnologies Gmbh 用於骨髓瘤和其他癌症免疫治疗的新型细胞表位和细胞表位组合物
GB201511191D0 (en) * 2015-06-25 2015-08-12 Immatics Biotechnologies Gmbh T-cell epitopes for the immunotherapy of myeloma
WO2017036369A1 (en) * 2015-09-03 2017-03-09 The University Of Hong Kong A monoclonal antibody for predicting tamoxifen response in breast cancer patients
CN105296613A (zh) * 2015-09-24 2016-02-03 郑州市职业病防治院 一种人TERF1基因rs3863242位点多态性检测技术
CN108026164A (zh) 2015-09-24 2018-05-11 梅约医学教育与研究基金会 通过质谱鉴定免疫球蛋白游离轻链
WO2017095632A1 (en) * 2015-11-30 2017-06-08 Mayo Foundation For Medical Education And Research Heatr1 as a marker for chemoresistance
CN105785013A (zh) * 2016-04-21 2016-07-20 卢连伟 一种辅助检测胰腺癌的胶体金免疫层析试纸及其制备方法
GB201608192D0 (en) * 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
JP7075125B2 (ja) * 2016-05-25 2022-05-25 イマティクス バイオテクノロジーズ ゲーエムベーハー 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ
CN115404196A (zh) 2016-07-13 2022-11-29 哈佛学院院长等 抗原呈递细胞模拟支架及其制备和使用方法
CN110418651A (zh) 2016-08-02 2019-11-05 哈佛学院院长等 用于调节免疫应答的生物材料
AU2017325022B2 (en) 2016-09-07 2022-10-13 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
CN107655985B (zh) * 2017-08-25 2020-05-26 南京农业大学 一种基于lc-ms-ms技术的体内蛋白质营养的评价方法
WO2019055634A1 (en) 2017-09-13 2019-03-21 Mayo Foundation For Medical Education And Research IDENTIFICATION AND MONITORING OF A MACROPHAGE APOPTOSIS INHIBITOR
EP3681907A4 (en) 2017-09-13 2021-07-07 Mayo Foundation for Medical Education and Research IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN J-CHAINS
JP2021520493A (ja) * 2018-04-03 2021-08-19 クリエイティクス エルエルシー 胃腸洗浄液試料における免疫グロブリンのグリカン結合パターンを評価するがん検出方法
WO2020061129A1 (en) 2018-09-19 2020-03-26 President And Fellows Of Harvard College Compositions and methods for labeling and modulation of cells in vitro and in vivo
EP3873528A4 (en) * 2018-10-29 2022-08-10 The Johns Hopkins University Rasopathy treatment
WO2020223646A1 (en) * 2019-05-02 2020-11-05 Creatics Llc Methods for cancer detection by evaluation of alpha-1-antitrypsin (aat) and chymotrypsin-like elastase in gastrointestinal lavage fluid samples
EP3987050A1 (en) * 2019-06-24 2022-04-27 Urteste S.A. Novel diagnostic marker for pancreatic cancer
WO2021061837A1 (en) 2019-09-23 2021-04-01 President And Fellows Of Harvard College Biomaterial-based antigen free vaccine and the use thereof
EP4045912A1 (en) * 2019-10-18 2022-08-24 Reccan Diagnostics AB Apparatuses and methods for detection of pancreatic cancer
EP4158354A1 (en) * 2020-05-26 2023-04-05 F. Hoffmann-La Roche AG Computer implemented method for calibrating a customer mass spectrometry instrument for quantifier-qualifier-ratio check
GB202010970D0 (en) 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
KR20230058045A (ko) * 2020-07-20 2023-05-02 다나-파버 캔서 인스티튜트 인크. 코로나바이러스 감염을 치료 및 예방하기 위한 방법 및 조성물
KR102448586B1 (ko) * 2020-10-08 2022-09-27 가톨릭대학교 산학협력단 췌장암 환자의 항암제 치료 반응성 예측용 마커
US20240026009A1 (en) * 2020-12-08 2024-01-25 Memorial Sloan Kettering Cancer Center Antibodies to galectin-3 and methods of use thereof
CN112461915B (zh) * 2020-12-08 2024-07-12 杭州汇健科技有限公司 一种与药物敏感相关的特征分子筛选、药敏程度检测、细胞亚型检测的方法
AU2021409465A1 (en) 2020-12-21 2023-08-03 Freenome Holdings, Inc. Markers for the early detection of colon cell proliferative disorders
WO2022171777A1 (en) * 2021-02-12 2022-08-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for prognosis and treating a patient suffering from cancer
US12179064B2 (en) * 2021-04-11 2024-12-31 Vikas Khurana System, apparatus and method for training a subject
KR20240017937A (ko) * 2021-06-07 2024-02-08 플래그쉽 파이어니어링 이노베이션스 Vii, 엘엘씨 치료제의 표적화된 전달을 위한 조성물 및 방법
CA3232274A1 (en) * 2021-09-20 2023-03-23 Jose P. Zevallos Drain fluid for diagnostics
US12152280B2 (en) 2021-09-20 2024-11-26 Droplet Biosciences, Inc. Drain fluid for diagnostics
US12416626B2 (en) * 2022-07-22 2025-09-16 Droplet Biosciences, Inc. Methods for evaluating candidate therapy efficacy based on changes in lymphatic fluid biomarkers
WO2024086298A2 (en) * 2022-10-20 2024-04-25 The Johns Hopkins University Hla class i and class ii-restricted t-cell epitopes in pancreatic cancer tissues and uses thereof
WO2024206856A2 (en) * 2023-03-30 2024-10-03 Thomas Jefferson University Dna-dependent synthesis of rna by dna polymerase theta variants

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3276968D1 (en) * 1982-08-09 1987-09-17 Centocor Inc Immunoassay for carbohydrate antigenic determinant
JPH0673470B2 (ja) * 1986-07-15 1994-09-21 協和醗酵工業株式会社 抗ヒト胃癌単クロ−ン性抗体ａｍｃ−４６２
US5359681A (en) 1993-01-11 1994-10-25 University Of Washington Fiber optic sensor and methods and apparatus relating thereto
US6924153B1 (en) 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
JPH11225800A (ja) * 1998-02-10 1999-08-24 Kureha Chem Ind Co Ltd 体液を用いた癌検出方法及びキット
US6447763B1 (en) * 1998-06-12 2002-09-10 Ian L. Gordon Method and system for production and collection of lavage induced stool (LIS) for chemical and biologic tests of cells
WO2002002762A1 (en) * 2000-07-03 2002-01-10 Mochida Pharmaceutical Co., Ltd. Novel lipase
US20050120393A1 (en) * 2001-08-03 2005-06-02 Origene Technologies, Inc. Full-length prostate selective polynucleotides and polypeptides
US7291324B2 (en) * 2002-10-22 2007-11-06 Braintree Laboratories Inc. Method of bowel cleansing
AU2003294828A1 (en) * 2002-12-17 2004-07-09 Sinogenomax Co. Ltd. Chinese National Human Genomecenter Specific markers for pancreatic cancer
CA2547355A1 (en) * 2003-11-26 2005-06-16 Dana-Farber Cancer Institute, Inc. Animal models of pancreatic adenocarcinoma and uses therefor
ATE427499T1 (de) 2004-05-21 2009-04-15 Inst Systems Biology Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen
EP1991872A1 (en) 2006-03-02 2008-11-19 Oncotherapy Science, Inc. Methods for diagnosing pancreatic cancer using reg4 protein
EP2816122A1 (en) * 2008-02-15 2014-12-24 Mayo Foundation For Medical Education And Research Detecting neoplasm from a stool sample
US20090258090A1 (en) 2008-04-11 2009-10-15 Braintree Laboratories, Inc. Colon cleansing solution
ES2533428T3 (es) * 2009-05-04 2015-04-10 F. Hoffmann-La Roche Ag Uso de DPPIV/Seprasa como un marcador para el cáncer
WO2011027311A2 (en) * 2009-09-03 2011-03-10 Koninklijke Philips Electronics N.V. Novel tumor markers
KR20120101054A (ko) * 2009-11-05 2012-09-12 유니버시티 오브 버지니아 페이턴트 파운데이션 암에 대한 바이오마커로서 플렉틴-1을 검출하기 위한 조성물 및 방법
EP3355057A3 (en) * 2010-06-01 2018-12-12 Metanomics Health GmbH Means and methods for diagnosing pancreatic cancer in a subject
SG187045A1 (en) * 2010-08-13 2013-02-28 Somalogic Inc Pancreatic cancer biomarkers and uses thereof
AU2011351990A1 (en) * 2010-12-29 2013-07-18 Expression Pathology, Inc. Protein biomarkers of recurrent breast cancer
JP5984795B2 (ja) * 2011-04-05 2016-09-06 オリンパス株式会社 膵疾患を検出するためのデータを収集する方法
HK1200037A1 (en) * 2011-09-12 2015-07-31 克里蒂科斯有限责任公司 Non-invasive methods of detecting target molecules

Also Published As

Publication number Publication date
US20160033511A1 (en) 2016-02-04
JP2020091295A (ja) 2020-06-11
JP6646571B2 (ja) 2020-02-14
CA2902841A1 (en) 2014-10-02
WO2014160499A2 (en) 2014-10-02
AU2020202066B2 (en) 2022-06-02
EP2972375A2 (en) 2016-01-20
JP7109008B2 (ja) 2022-08-10
WO2014160499A3 (en) 2015-01-29
JP2022141755A (ja) 2022-09-29
AU2022224782A1 (en) 2022-09-22
JP2016519285A (ja) 2016-06-30
US20220128563A1 (en) 2022-04-28
US20190234951A1 (en) 2019-08-01
HK1214652A1 (zh) 2016-07-29
AU2020202066A1 (en) 2020-04-09

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