AU2012340344B2 - Microfluidic apparatus, method, and applications - Google Patents
Microfluidic apparatus, method, and applications Download PDFInfo
- Publication number
- AU2012340344B2 AU2012340344B2 AU2012340344A AU2012340344A AU2012340344B2 AU 2012340344 B2 AU2012340344 B2 AU 2012340344B2 AU 2012340344 A AU2012340344 A AU 2012340344A AU 2012340344 A AU2012340344 A AU 2012340344A AU 2012340344 B2 AU2012340344 B2 AU 2012340344B2
- Authority
- AU
- Australia
- Prior art keywords
- liquid
- tube
- nucleic acid
- tissue sample
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
- C07H1/08—Separation; Purification from natural products
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161561007P | 2011-11-17 | 2011-11-17 | |
| US61/561,007 | 2011-11-17 | ||
| PCT/US2012/065452 WO2013074885A1 (en) | 2011-11-17 | 2012-11-16 | Microfluidic apparatus, method, and applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2012340344A1 AU2012340344A1 (en) | 2014-05-01 |
| AU2012340344B2 true AU2012340344B2 (en) | 2015-10-29 |
Family
ID=48430176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012340344A Active AU2012340344B2 (en) | 2011-11-17 | 2012-11-16 | Microfluidic apparatus, method, and applications |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US8852919B2 (enExample) |
| EP (1) | EP2780453B1 (enExample) |
| JP (3) | JP2014533952A (enExample) |
| CN (1) | CN104053774B (enExample) |
| AU (1) | AU2012340344B2 (enExample) |
| IN (1) | IN2014CN04296A (enExample) |
| WO (1) | WO2013074885A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2468862A1 (en) * | 2010-12-23 | 2012-06-27 | Qiagen GmbH | Method and kit for processing wax-embedded biological samples |
| AU2013323586B2 (en) * | 2012-09-28 | 2019-07-11 | Cepheid | Methods for DNA and RNA extraction from fixed paraffin-embedded tissue samples |
| CN204727866U (zh) | 2014-03-31 | 2015-10-28 | 博奥生物集团有限公司 | 一种集核酸扩增和微阵列检测于一体的微流控装置 |
| WO2016168429A1 (en) * | 2015-04-14 | 2016-10-20 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Method and apparatus for extracting and collecting single cells from formalin-fixed paraffin embedded tissues |
| DE102016208936A1 (de) * | 2016-05-24 | 2017-11-30 | Robert Bosch Gmbh | Mikrofluidische Vorrichtung und Verfahren zur Probenaufbereitung von Paraffin-eigebettetem Gewebe |
| WO2018119295A1 (en) * | 2016-12-22 | 2018-06-28 | Ventana Medical Systems, Inc. | Fully automated nucleic acid extraction method for tissue samples |
| DE102018200520A1 (de) * | 2018-01-15 | 2019-07-18 | Robert Bosch Gmbh | Verfahren zum Bereitstellen einer Lösung der Substanz in einer mikrofluidischen Vorrichtung |
| US11513041B2 (en) | 2018-10-19 | 2022-11-29 | Polyvalor, Limited Partnership | Medium-embedded samples |
| WO2020185585A1 (en) * | 2019-03-08 | 2020-09-17 | Rarecyte, Inc. | Device, system, and method for selecting a target analyte |
| US11332777B1 (en) | 2021-10-28 | 2022-05-17 | URIT Medical Electronic Co., Ltd. | Methods and reagent kits for bisulfite conversion of DNA |
| DE102022111890B3 (de) | 2022-05-12 | 2023-03-16 | Dermagnostix GmbH | Verfahren zur Deparaffinierung von Formalin-fixiertem Paraffin-eingebettetem Gewebe |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110003369A1 (en) * | 2009-07-01 | 2011-01-06 | Kirsch Christoph | Method for the deparaffinisation of biological specimens |
| WO2012085261A1 (en) * | 2010-12-23 | 2012-06-28 | Qiagen Gmbh | Method and kit for processing wax-embedded biological samples |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5552087A (en) * | 1993-11-15 | 1996-09-03 | Ventana Medical Systems, Inc. | High temperature evaporation inhibitor liquid |
| US5856174A (en) * | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
| US5863502A (en) * | 1996-01-24 | 1999-01-26 | Sarnoff Corporation | Parallel reaction cassette and associated devices |
| US6855559B1 (en) * | 1998-09-03 | 2005-02-15 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
| US7410753B2 (en) | 1998-09-03 | 2008-08-12 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
| US6544798B1 (en) | 1999-02-26 | 2003-04-08 | Ventana Medical Systems, Inc. | Removal of embedding media from biological samples and cell conditioning on automated staining instruments |
| US6469159B1 (en) | 1999-04-26 | 2002-10-22 | Robert T. Belly | Methods for extracting nucleic acids from tissue samples and paraffin-embedded tissues |
| US6248535B1 (en) | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| US7364846B2 (en) * | 2002-10-11 | 2008-04-29 | Molecular Devices Corporation | Gene expression profiling from FFPE samples |
| US20050142570A1 (en) | 2003-12-24 | 2005-06-30 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and sedimenting reagent |
| AU2006249956A1 (en) * | 2005-05-24 | 2006-11-30 | Angros, Lee H | In situ heat induced antigen recovery and staining apparatus and method |
| US7544471B2 (en) * | 2005-07-30 | 2009-06-09 | Agilent Technologies, Inc. | Preparing RNA from a wax-embedded tissue specimen |
| WO2009049268A1 (en) * | 2007-10-12 | 2009-04-16 | Rheonix, Inc. | Integrated microfluidic device and methods |
| DE102008029356A1 (de) | 2008-06-20 | 2009-12-24 | Siemens Healthcare Diagnostics Gmbh | Verfahren zur Aufreinigung von Nukleinsäuren, insbesondere aus fixiertem Gewebe |
| WO2010003463A1 (en) * | 2008-07-11 | 2010-01-14 | Metabolic Explorer | Method for polymerising glycolic acid with microorganisms |
| DE102008061714A1 (de) * | 2008-12-12 | 2010-06-17 | Siemens Healthcare Diagnostics Inc., Deerfield | Verfahren zur Aufreinigung von Nukleinsäuren, inbesondere aus fixiertem Gewebe |
| WO2011008217A1 (en) | 2009-07-17 | 2011-01-20 | Canon U.S. Life Sciences, Inc. | Methods and systems for dna isolation on a microfluidic device |
| WO2011104032A1 (en) * | 2010-02-26 | 2011-09-01 | Qiagen Gmbh | Method for isolating rna from a rna and dna containing sample |
| JP2011213804A (ja) * | 2010-03-31 | 2011-10-27 | Sumitomo Chemical Co Ltd | 予備重合方法、予備重合済付加重合触媒成分およびそれを用いる付加重合体の製造方法 |
| WO2012024103A2 (en) | 2010-08-17 | 2012-02-23 | Rheonix, Inc. | Thermocycler seal composition, method, and application |
| AU2011315926B2 (en) | 2010-10-14 | 2015-12-10 | Rheonix, Inc. | Quantitative multiplexed identification of nucleic acid targets |
-
2012
- 2012-11-16 JP JP2014542481A patent/JP2014533952A/ja active Pending
- 2012-11-16 EP EP12850325.7A patent/EP2780453B1/en active Active
- 2012-11-16 AU AU2012340344A patent/AU2012340344B2/en active Active
- 2012-11-16 WO PCT/US2012/065452 patent/WO2013074885A1/en not_active Ceased
- 2012-11-16 CN CN201280056605.1A patent/CN104053774B/zh active Active
- 2012-11-16 IN IN4296CHN2014 patent/IN2014CN04296A/en unknown
- 2012-11-16 US US13/678,732 patent/US8852919B2/en active Active
-
2014
- 2014-09-05 US US14/478,012 patent/US10865436B2/en active Active
- 2014-09-05 US US14/478,049 patent/US10081828B2/en active Active
-
2016
- 2016-07-26 JP JP2016146351A patent/JP2016187355A/ja active Pending
-
2018
- 2018-05-08 JP JP2018089843A patent/JP6655652B2/ja not_active Expired - Fee Related
-
2020
- 2020-11-09 US US17/092,379 patent/US11795493B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110003369A1 (en) * | 2009-07-01 | 2011-01-06 | Kirsch Christoph | Method for the deparaffinisation of biological specimens |
| WO2012085261A1 (en) * | 2010-12-23 | 2012-06-28 | Qiagen Gmbh | Method and kit for processing wax-embedded biological samples |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012340344A1 (en) | 2014-05-01 |
| JP2018148904A (ja) | 2018-09-27 |
| US10081828B2 (en) | 2018-09-25 |
| US20140377854A1 (en) | 2014-12-25 |
| JP6655652B2 (ja) | 2020-02-26 |
| CN104053774B (zh) | 2016-09-07 |
| EP2780453A1 (en) | 2014-09-24 |
| US20210054440A1 (en) | 2021-02-25 |
| US20130164826A1 (en) | 2013-06-27 |
| IN2014CN04296A (enExample) | 2015-09-04 |
| CN104053774A (zh) | 2014-09-17 |
| US8852919B2 (en) | 2014-10-07 |
| EP2780453B1 (en) | 2017-03-29 |
| EP2780453A4 (en) | 2015-06-03 |
| JP2014533952A (ja) | 2014-12-18 |
| US10865436B2 (en) | 2020-12-15 |
| US20150056650A1 (en) | 2015-02-26 |
| US11795493B2 (en) | 2023-10-24 |
| WO2013074885A1 (en) | 2013-05-23 |
| JP2016187355A (ja) | 2016-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |