JP2014533952A - 微小流体装置、方法および応用 - Google Patents

微小流体装置、方法および応用 Download PDF

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Publication number
JP2014533952A
JP2014533952A JP2014542481A JP2014542481A JP2014533952A JP 2014533952 A JP2014533952 A JP 2014533952A JP 2014542481 A JP2014542481 A JP 2014542481A JP 2014542481 A JP2014542481 A JP 2014542481A JP 2014533952 A JP2014533952 A JP 2014533952A
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Japan
Prior art keywords
liquid
nucleic acid
tube
acid purification
container
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JP2014542481A
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English (en)
Japanese (ja)
Inventor
ポン・ジョウ
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Rheonix Inc
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Rheonix Inc
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Publication of JP2014533952A publication Critical patent/JP2014533952A/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2014542481A 2011-11-17 2012-11-16 微小流体装置、方法および応用 Pending JP2014533952A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161561007P 2011-11-17 2011-11-17
US61/561,007 2011-11-17
PCT/US2012/065452 WO2013074885A1 (en) 2011-11-17 2012-11-16 Microfluidic apparatus, method, and applications

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016146351A Division JP2016187355A (ja) 2011-11-17 2016-07-26 微小流体装置、方法および応用

Publications (1)

Publication Number Publication Date
JP2014533952A true JP2014533952A (ja) 2014-12-18

Family

ID=48430176

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2014542481A Pending JP2014533952A (ja) 2011-11-17 2012-11-16 微小流体装置、方法および応用
JP2016146351A Pending JP2016187355A (ja) 2011-11-17 2016-07-26 微小流体装置、方法および応用
JP2018089843A Expired - Fee Related JP6655652B2 (ja) 2011-11-17 2018-05-08 微小流体装置、方法および応用

Family Applications After (2)

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JP2016146351A Pending JP2016187355A (ja) 2011-11-17 2016-07-26 微小流体装置、方法および応用
JP2018089843A Expired - Fee Related JP6655652B2 (ja) 2011-11-17 2018-05-08 微小流体装置、方法および応用

Country Status (7)

Country Link
US (4) US8852919B2 (enExample)
EP (1) EP2780453B1 (enExample)
JP (3) JP2014533952A (enExample)
CN (1) CN104053774B (enExample)
AU (1) AU2012340344B2 (enExample)
IN (1) IN2014CN04296A (enExample)
WO (1) WO2013074885A1 (enExample)

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EP2468862A1 (en) * 2010-12-23 2012-06-27 Qiagen GmbH Method and kit for processing wax-embedded biological samples
CA2886389A1 (en) * 2012-09-28 2014-04-03 Cepheid Methods for dna and rna extraction from fixed paraffin-embedded tissue samples
CN104946510B (zh) 2014-03-31 2017-06-06 博奥生物集团有限公司 集核酸扩增和微阵列检测于一体的微流控装置
WO2016168429A1 (en) * 2015-04-14 2016-10-20 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Method and apparatus for extracting and collecting single cells from formalin-fixed paraffin embedded tissues
DE102016208936A1 (de) * 2016-05-24 2017-11-30 Robert Bosch Gmbh Mikrofluidische Vorrichtung und Verfahren zur Probenaufbereitung von Paraffin-eigebettetem Gewebe
CN110050070B (zh) * 2016-12-22 2023-12-22 文塔纳医疗系统公司 用于组织样品的全自动化核酸提取方法
DE102018200520A1 (de) 2018-01-15 2019-07-18 Robert Bosch Gmbh Verfahren zum Bereitstellen einer Lösung der Substanz in einer mikrofluidischen Vorrichtung
US11513041B2 (en) 2018-10-19 2022-11-29 Polyvalor, Limited Partnership Medium-embedded samples
JP2022524120A (ja) * 2019-03-08 2022-04-27 レアサイト インコーポレイテッド 標的分析物を選択する器具、システムおよび方法
US11332777B1 (en) * 2021-10-28 2022-05-17 URIT Medical Electronic Co., Ltd. Methods and reagent kits for bisulfite conversion of DNA
DE102022111890B3 (de) 2022-05-12 2023-03-16 Dermagnostix GmbH Verfahren zur Deparaffinierung von Formalin-fixiertem Paraffin-eingebettetem Gewebe

Citations (3)

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JP2009506300A (ja) * 2005-05-24 2009-02-12 リー エイチ． アングロス， ｉｎｓｉｔｕ熱誘導抗原回復・着色装置および方法
JP2011501665A (ja) * 2007-10-12 2011-01-13 レオニックス，インコーポレイテッド 統合型マイクロ流体デバイスおよび方法
WO2011104027A1 (en) * 2010-02-26 2011-09-01 Qiagen Gmbh Process for parallel isolation and/or purification of rna and dna

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US5552087A (en) * 1993-11-15 1996-09-03 Ventana Medical Systems, Inc. High temperature evaporation inhibitor liquid
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US6855559B1 (en) * 1998-09-03 2005-02-15 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US7410753B2 (en) 1998-09-03 2008-08-12 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6544798B1 (en) 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6469159B1 (en) 1999-04-26 2002-10-22 Robert T. Belly Methods for extracting nucleic acids from tissue samples and paraffin-embedded tissues
US6248535B1 (en) 1999-12-20 2001-06-19 University Of Southern California Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
US7364846B2 (en) * 2002-10-11 2008-04-29 Molecular Devices Corporation Gene expression profiling from FFPE samples
US20050142570A1 (en) 2003-12-24 2005-06-30 3M Innovative Properties Company Methods for nucleic acid isolation and kits using a microfluidic device and sedimenting reagent
US7544471B2 (en) * 2005-07-30 2009-06-09 Agilent Technologies, Inc. Preparing RNA from a wax-embedded tissue specimen
DE102008029356A1 (de) 2008-06-20 2009-12-24 Siemens Healthcare Diagnostics Gmbh Verfahren zur Aufreinigung von Nukleinsäuren, insbesondere aus fixiertem Gewebe
WO2010003463A1 (en) * 2008-07-11 2010-01-14 Metabolic Explorer Method for polymerising glycolic acid with microorganisms
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JP2009506300A (ja) * 2005-05-24 2009-02-12 リー エイチ． アングロス， ｉｎｓｉｔｕ熱誘導抗原回復・着色装置および方法
JP2011501665A (ja) * 2007-10-12 2011-01-13 レオニックス，インコーポレイテッド 統合型マイクロ流体デバイスおよび方法
WO2011104027A1 (en) * 2010-02-26 2011-09-01 Qiagen Gmbh Process for parallel isolation and/or purification of rna and dna
WO2011104032A1 (en) * 2010-02-26 2011-09-01 Qiagen Gmbh Method for isolating rna from a rna and dna containing sample

Also Published As

Publication number Publication date
US10865436B2 (en) 2020-12-15
CN104053774B (zh) 2016-09-07
JP2018148904A (ja) 2018-09-27
EP2780453A4 (en) 2015-06-03
US20150056650A1 (en) 2015-02-26
CN104053774A (zh) 2014-09-17
US8852919B2 (en) 2014-10-07
EP2780453A1 (en) 2014-09-24
IN2014CN04296A (enExample) 2015-09-04
US10081828B2 (en) 2018-09-25
US11795493B2 (en) 2023-10-24
JP6655652B2 (ja) 2020-02-26
WO2013074885A1 (en) 2013-05-23
US20210054440A1 (en) 2021-02-25
JP2016187355A (ja) 2016-11-04
AU2012340344A1 (en) 2014-05-01
AU2012340344B2 (en) 2015-10-29
US20140377854A1 (en) 2014-12-25
US20130164826A1 (en) 2013-06-27
EP2780453B1 (en) 2017-03-29

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