AU2012285803B2 - Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof - Google Patents
Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof Download PDFInfo
- Publication number
- AU2012285803B2 AU2012285803B2 AU2012285803A AU2012285803A AU2012285803B2 AU 2012285803 B2 AU2012285803 B2 AU 2012285803B2 AU 2012285803 A AU2012285803 A AU 2012285803A AU 2012285803 A AU2012285803 A AU 2012285803A AU 2012285803 B2 AU2012285803 B2 AU 2012285803B2
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- AU
- Australia
- Prior art keywords
- biomass
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
- C11B1/10—Production of fats or fatty oils from raw materials by extracting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
- C12N1/125—Unicellular algae isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/89—Algae ; Processes using algae
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Physiology (AREA)
- Molecular Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Insects & Arthropods (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2016256769A AU2016256769B2 (en) | 2011-07-21 | 2016-11-10 | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161510464P | 2011-07-21 | 2011-07-21 | |
| US61/510,464 | 2011-07-21 | ||
| PCT/US2012/047728 WO2013013208A2 (en) | 2011-07-21 | 2012-07-20 | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016256769A Division AU2016256769B2 (en) | 2011-07-21 | 2016-11-10 | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2012285803A1 AU2012285803A1 (en) | 2014-02-20 |
| AU2012285803B2 true AU2012285803B2 (en) | 2016-08-25 |
Family
ID=47558749
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012285803A Active AU2012285803B2 (en) | 2011-07-21 | 2012-07-20 | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| AU2016256769A Active AU2016256769B2 (en) | 2011-07-21 | 2016-11-10 | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016256769A Active AU2016256769B2 (en) | 2011-07-21 | 2016-11-10 | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
Country Status (20)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3118954B2 (ja) | 1992-05-14 | 2000-12-18 | 石川島播磨重工業株式会社 | 偏平ブロー成形装置 |
| JP3196326B2 (ja) | 1992-06-22 | 2001-08-06 | 石川島播磨重工業株式会社 | 偏平ブロー成形装置 |
| JP3196316B2 (ja) | 1992-05-20 | 2001-08-06 | 石川島播磨重工業株式会社 | ブロー成形装置 |
| JP3125443B2 (ja) | 1992-07-02 | 2001-01-15 | 石川島播磨重工業株式会社 | 偏平ブロー成形装置 |
| JP3196323B2 (ja) | 1992-06-09 | 2001-08-06 | 石川島播磨重工業株式会社 | 偏平ブロー成形機のパリソン皺矯正装置 |
| CA2993690C (en) * | 2010-01-19 | 2022-03-22 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| MX342216B (es) | 2011-07-21 | 2016-09-20 | Dsm Ip Assets Bv | Composiciones de acidos grasos. |
| US9587215B2 (en) | 2014-08-07 | 2017-03-07 | General Electric Company | Devices, systems and methods for automated transfer of a sample |
| CA2958439C (en) | 2014-10-02 | 2022-09-20 | Evonik Industries Ag | Feedstuff of high abrasion resistance and good stability in water, containing pufas |
| CN107075540A (zh) | 2014-10-02 | 2017-08-18 | 赢创德固赛有限公司 | 用于制备具有高细胞稳定性的含pufa生物质的方法 |
| CN106793803B (zh) * | 2014-10-02 | 2021-03-09 | 赢创运营有限公司 | 通过挤压含pufa的生物质来制备含pufa的饲料的方法 |
| BR112017005388B1 (pt) | 2014-10-02 | 2022-09-13 | Evonik Operations Gmbh | Alimento para animais contendo biomassa de aurantiochytrium |
| CN104962589B (zh) * | 2015-08-05 | 2019-02-26 | 嘉必优生物技术（武汉）股份有限公司 | 一种富含磷脂型多不饱和脂肪酸的微生物油脂及制备方法 |
| JP6998934B2 (ja) * | 2016-07-13 | 2022-01-18 | エボニック オペレーションズ ゲーエムベーハー | 脂質含有細胞から脂質を単離する方法 |
| KR102405390B1 (ko) | 2016-07-13 | 2022-06-03 | 에보닉 오퍼레이션스 게엠베하 | 용해된 지질을 함유하는 바이오매스로부터 지질을 분리하는 방법 |
| CA3034122A1 (en) | 2016-08-19 | 2018-02-22 | Noblegen Inc. | Methods and uses of dissolved organic material fractions for binding metal ions |
| ES2872009T3 (es) | 2016-12-27 | 2021-11-02 | Evonik Degussa Gmbh | Método de aislamiento de lípidos a partir de una biomasa que contiene lípidos |
| US11053139B2 (en) | 2017-04-07 | 2021-07-06 | Noblegen Inc. | Methods and uses of encapsulated exudates and dried euglena biomass for binding metal |
| EP3470502A1 (en) | 2017-10-13 | 2019-04-17 | Evonik Degussa GmbH | Method of separating lipids from a lysed lipids containing biomass |
| EP3527664A1 (en) | 2018-02-15 | 2019-08-21 | Evonik Degussa GmbH | Method of isolating lipids from a lipids containing biomass |
| WO2019219396A1 (en) | 2018-05-15 | 2019-11-21 | Evonik Operations Gmbh | Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion |
| WO2019219443A1 (en) | 2018-05-15 | 2019-11-21 | Evonik Operations Gmbh | Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica |
| US20210277430A1 (en) * | 2020-03-09 | 2021-09-09 | Lanzatech, Inc. | Fermentation process for the production of lipids |
| KR102614551B1 (ko) * | 2020-12-07 | 2023-12-15 | 씨제이제일제당 주식회사 | 단일 미세조류로부터 단백질 및 오메가-3 지방산을 포함하는 바이오매스를 제조하는 방법 및 이에 의해 제조된 바이오매스 |
| WO2023144707A1 (en) | 2022-01-25 | 2023-08-03 | Dsm Ip Assets B.V. | Media refinement and nutrient feeding approaches to increase polyunsaturated fatty acid production |
| CN115927005B (zh) * | 2022-10-14 | 2024-11-22 | 广西中医药大学 | 两面针内生真菌y118的固体发酵培养基及其制备和培养方法 |
| CN116479063B (zh) * | 2023-05-04 | 2024-02-20 | 厦门汇盛生物有限公司 | 一种ω-3多不饱和脂肪酸的生产方法 |
| WO2025019424A1 (en) * | 2023-07-14 | 2025-01-23 | Dsm Ip Assets B.V. | Microbial oils having high epa content and methods of making the same |
| CN118755584B (zh) * | 2024-08-06 | 2025-04-29 | 杭州合碳创物科技有限公司 | 一种高产epa的裂殖壶菌及其应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1994028913A1 (en) * | 1993-06-09 | 1994-12-22 | Martek Biosciences Corporation | Methods and pharmaceutical compositions useful for treating neurological disorders |
| US6607900B2 (en) * | 2000-01-28 | 2003-08-19 | Martek Biosciences Boulder Corporation | Enhanced production of lipids containing polyenoic fatty acid by very high density cultures of eukaryotic microbes in fermentors |
| US7005280B2 (en) * | 1988-09-07 | 2006-02-28 | Martek Biosciences Corporation | Method of producing lipids by growing microorganisms of the order thraustochytriales |
| US20100331561A1 (en) * | 2003-12-30 | 2010-12-30 | Dsm Ip Assets B.V. | Deaeration process |
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| US5130242A (en) | 1988-09-07 | 1992-07-14 | Phycotech, Inc. | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
| WO1996033263A1 (en) | 1995-04-17 | 1996-10-24 | JAPAN, represented by DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY | Novel microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fatty acids by using the microorganisms |
| US6255505B1 (en) * | 1996-03-28 | 2001-07-03 | Gist-Brocades, B.V. | Microbial polyunsaturated fatty acid containing oil from pasteurised biomass |
| AU748220C (en) | 1997-08-01 | 2003-02-27 | Martek Biosciences Corporation | DHA-containing nutritional compositions and methods for their production |
| KR101591834B1 (ko) | 2000-01-19 | 2016-02-18 | 마텍 바이오싸이언스스 코포레이션 | 무용매 추출 방법 |
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| DE10102337A1 (de) * | 2001-01-19 | 2002-07-25 | Basf Plant Science Gmbh | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren, neue Biosynthesegene sowie neue pflanzliche Expressionskonstrukte |
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| JP4280158B2 (ja) | 2002-12-27 | 2009-06-17 | 富士フイルム株式会社 | ドコサヘキサエン酸生産能を有する微生物及びその利用 |
| US20050019880A1 (en) * | 2003-03-31 | 2005-01-27 | Council Of Scientific And Industrial Research | Method of enhancing levels of polyunsaturated fatty acids in thraustochytrid protists |
| ES2529572T3 (es) * | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| US9023616B2 (en) * | 2006-08-01 | 2015-05-05 | Dsm Nutritional Products Ag | Oil producing microbes and method of modification thereof |
| CL2008002020A1 (es) * | 2007-07-12 | 2008-11-14 | Ocean Nutrition Canada Ltd | Metodo de modificacion de un aceite, que comprende hidrolizar gliceridos con una solucion de lipasa thermomyces lanuginosus, separar la fraccion de acido graso saturado de la fraccion de glicerido hidrolizado y esterificar los gliceridos hidrolizados en la presencia de candida antarctica lipasa b; y composicion de aceite. |
| KR101650584B1 (ko) * | 2007-08-31 | 2016-08-23 | 디에스엠 아이피 어셋츠 비.브이. | 다중불포화된 지방산 함유 고체 지방 조성물 및 그의 용도 및 생산 |
| US9695372B2 (en) * | 2007-09-11 | 2017-07-04 | Sapphire Energy, Inc. | Methods of producing organic products with photosynthetic organisms |
| EA019387B1 (ru) * | 2007-09-12 | 2014-03-31 | Мартек Биосайнсиз Корпорейшн | Способ получения биологического масла и его использование в способе получения биодизеля |
| US8323935B2 (en) * | 2007-10-03 | 2012-12-04 | E I Du Pont De Nemours And Company | Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production |
| EP4183883A1 (en) * | 2009-03-19 | 2023-05-24 | DSM IP Assets B.V. | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| US8207363B2 (en) | 2009-03-19 | 2012-06-26 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| EP2519625B1 (en) * | 2009-12-28 | 2018-09-26 | DSM IP Assets B.V. | Recombinant thraustochytrids that grow on sucrose, and compositions, methods of making, and uses thereof |
| CA2993690C (en) * | 2010-01-19 | 2022-03-22 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| EP2561050A1 (en) * | 2010-04-22 | 2013-02-27 | E.I. Du Pont De Nemours And Company | Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass |
| DK2580342T3 (da) * | 2010-06-09 | 2019-07-01 | Fermentalg | Sammensætninger omfattende eicosapentaensyre egnet til høj oprensning |
| EP2734626B1 (en) * | 2011-07-21 | 2020-12-16 | DSM IP Assets B.V. | Microbial oils enriched in polyunsaturated fatty acids |
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2012
- 2012-07-20 SG SG10201605966TA patent/SG10201605966TA/en unknown
- 2012-07-20 PH PH1/2014/500169A patent/PH12014500169B1/en unknown
- 2012-07-20 CN CN201280035935.2A patent/CN104011217B/zh active Active
- 2012-07-20 ES ES15171724T patent/ES2859752T3/es active Active
- 2012-07-20 JP JP2014521849A patent/JP6338285B2/ja not_active Expired - Fee Related
- 2012-07-20 AU AU2012285803A patent/AU2012285803B2/en active Active
- 2012-07-20 KR KR1020197019037A patent/KR102158437B1/ko active Active
- 2012-07-20 CN CN202411870122.6A patent/CN119899748A/zh active Pending
- 2012-07-20 EP EP12815192.5A patent/EP2734630B1/en active Active
- 2012-07-20 MX MX2017012687A patent/MX385408B/es unknown
- 2012-07-20 CA CA2842374A patent/CA2842374C/en active Active
- 2012-07-20 EP EP20207686.5A patent/EP3831952A1/en active Pending
- 2012-07-20 EA EA201400151A patent/EA034980B1/ru not_active IP Right Cessation
- 2012-07-20 EP EP15171724.6A patent/EP3050972B1/en active Active
- 2012-07-20 KR KR1020147004428A patent/KR102038715B1/ko active Active
- 2012-07-20 MY MYPI2014700130A patent/MY169454A/en unknown
- 2012-07-20 CN CN201510526715.5A patent/CN105255738B/zh active Active
- 2012-07-20 BR BR122015020130-6A patent/BR122015020130A2/pt not_active Application Discontinuation
- 2012-07-20 ES ES12815192T patent/ES2774778T3/es active Active
- 2012-07-20 AR ARP120102657A patent/AR087944A1/es unknown
- 2012-07-20 WO PCT/US2012/047728 patent/WO2013013208A2/en not_active Ceased
- 2012-07-20 MX MX2014000759A patent/MX351174B/es active IP Right Grant
- 2012-07-20 BR BR112014001443-4A patent/BR112014001443B1/pt active IP Right Grant
- 2012-07-20 DK DK15171724.6T patent/DK3050972T3/da active
- 2012-07-20 US US13/554,975 patent/US9045785B2/en active Active
- 2012-07-20 EP EP25170782.4A patent/EP4585049A2/en active Pending
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2014
- 2014-01-16 IL IL230500A patent/IL230500B/en active IP Right Grant
- 2014-01-21 CL CL2014000156A patent/CL2014000156A1/es unknown
- 2014-01-24 ZA ZA2014/00620A patent/ZA201400620B/en unknown
- 2014-12-10 US US14/566,500 patent/US20150094382A1/en not_active Abandoned
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2015
- 2015-04-23 ZA ZA2015/02764A patent/ZA201502764B/en unknown
- 2015-04-28 US US14/698,378 patent/US20150223492A1/en not_active Abandoned
- 2015-05-07 CL CL2015001217A patent/CL2015001217A1/es unknown
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2016
- 2016-11-10 AU AU2016256769A patent/AU2016256769B2/en active Active
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2017
- 2017-05-18 US US15/598,812 patent/US20170245523A1/en not_active Abandoned
- 2017-05-22 JP JP2017100780A patent/JP2017200480A/ja active Pending
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2019
- 2019-11-07 JP JP2019202514A patent/JP7134938B2/ja active Active
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2021
- 2021-11-05 US US17/519,961 patent/US20220322705A1/en active Pending
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2026
- 2026-02-06 US US19/532,377 patent/US20260165347A1/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7005280B2 (en) * | 1988-09-07 | 2006-02-28 | Martek Biosciences Corporation | Method of producing lipids by growing microorganisms of the order thraustochytriales |
| WO1994028913A1 (en) * | 1993-06-09 | 1994-12-22 | Martek Biosciences Corporation | Methods and pharmaceutical compositions useful for treating neurological disorders |
| US6607900B2 (en) * | 2000-01-28 | 2003-08-19 | Martek Biosciences Boulder Corporation | Enhanced production of lipids containing polyenoic fatty acid by very high density cultures of eukaryotic microbes in fermentors |
| US20100331561A1 (en) * | 2003-12-30 | 2010-12-30 | Dsm Ip Assets B.V. | Deaeration process |
Non-Patent Citations (4)
| Title |
|---|
| BURJA et al., Applied Microbiology and Biotechnology, 2006, vol. 72, no. 6, pages 1161-1169 * |
| HOSHIDA et. al., Journal of Applied Phycology, 2005, vol. 17, pages 29-34 * |
| LEWIS T.E et al., Marine Biotechnology, 1999, Vol. 1, pages 580-587 * |
| YONGMANITCHAI et al., Applied and Environmental Microbiology, 1991, vol. 57, no. 2, pages 419-425 * |
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