AU2012264458B2 - Method for detecting and quantifying a target molecule in a tissue - Google Patents

Method for detecting and quantifying a target molecule in a tissue Download PDF

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Publication number
AU2012264458B2
AU2012264458B2 AU2012264458A AU2012264458A AU2012264458B2 AU 2012264458 B2 AU2012264458 B2 AU 2012264458B2 AU 2012264458 A AU2012264458 A AU 2012264458A AU 2012264458 A AU2012264458 A AU 2012264458A AU 2012264458 B2 AU2012264458 B2 AU 2012264458B2
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Australia
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tissue
molecule
sample
slice
standard
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AU2012264458A
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AU2012264458A1 (en
Inventor
David BONNEL
Jonathan STAUBER
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Imabiotech
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Imabiotech
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2866—Grinding or homogeneising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N2001/2893—Preparing calibration standards

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
AU2012264458A 2011-05-31 2012-05-29 Method for detecting and quantifying a target molecule in a tissue Active AU2012264458B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1154731 2011-05-31
FR1154731A FR2976076B1 (fr) 2011-05-31 2011-05-31 Procede de detection et de quantification d'une molecule cible dans un tissu
PCT/FR2012/051205 WO2012164221A1 (fr) 2011-05-31 2012-05-29 Procede de detection et de quantification d'une molecule cible dans un tissu

Publications (2)

Publication Number Publication Date
AU2012264458A1 AU2012264458A1 (en) 2014-01-09
AU2012264458B2 true AU2012264458B2 (en) 2015-09-24

Family

ID=46420402

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012264458A Active AU2012264458B2 (en) 2011-05-31 2012-05-29 Method for detecting and quantifying a target molecule in a tissue

Country Status (12)

Country Link
US (1) US10132796B2 (OSRAM)
EP (1) EP2715310B1 (OSRAM)
JP (1) JP6170911B2 (OSRAM)
KR (1) KR102004350B1 (OSRAM)
CN (1) CN103688151B (OSRAM)
AU (1) AU2012264458B2 (OSRAM)
CA (1) CA2837153C (OSRAM)
DK (1) DK2715310T3 (OSRAM)
ES (1) ES2922478T3 (OSRAM)
FR (1) FR2976076B1 (OSRAM)
IN (1) IN2013MN02451A (OSRAM)
WO (1) WO2012164221A1 (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014128309A1 (en) 2013-02-25 2014-08-28 Imabiotech Method to evaluate the tissue targeting of a molecule of interest
CN103336128A (zh) * 2013-06-08 2013-10-02 天津药物研究院 一种检测小分子多肽类药物组织分布的方法
KR102696044B1 (ko) * 2015-11-06 2024-08-16 벤타나 메디컬 시스템즈, 인코포레이티드 대표 진단법
KR101996666B1 (ko) * 2016-05-02 2019-07-04 주식회사 엘지화학 정량 분석 방법
US11289316B2 (en) 2018-05-30 2022-03-29 Shimadzu Corporation Spectrum data processing device and analyzer
EP4111174A4 (en) * 2020-02-27 2024-03-27 Nicoya Lifesciences, Inc. SYSTEMS AND METHODS FOR CHARACTERIZING AN ASSAY FROM REGIONS OF INTEREST USING OPTICAL REACTIONS
WO2021175842A1 (en) 2020-03-02 2021-09-10 Universiteit Maastricht Quality control standards for mass spectrometry imaging
CN115326915A (zh) * 2022-08-01 2022-11-11 中央民族大学 一种植物组织微阵列maldi-msi高通量分析方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL149171A0 (en) * 1999-11-16 2002-11-10 Genentech Inc Elisa for vegf
KR20050070034A (ko) * 2002-10-04 2005-07-05 미쯔비시 웰 파마 가부시키가이샤 질량 분석용 플레이트, 그 제조 방법 및 그 용도
US20040096907A1 (en) * 2002-11-06 2004-05-20 Bernd Bohrmann Quantification of beta amyloid
JP2005181011A (ja) * 2003-12-17 2005-07-07 Yoshio Yamauchi タンパク質解析方法
JP4547173B2 (ja) 2004-03-17 2010-09-22 シスメックス株式会社 糖尿病診療支援システム
CA2611266C (en) 2005-06-07 2015-11-24 Centre National De La Recherche Scientifique (Cnrs) Use of conjugates with linkers cleavable by photodissociation or fragmentation for mass spectrometry analysis of tissue sections
EP2163900A1 (en) 2008-09-04 2010-03-17 Commissariat A L'energie Atomique New method of imaging by mass spectrometry and new mass tag associated trityl derivatives
WO2010041459A1 (ja) * 2008-10-08 2010-04-15 積水メディカル株式会社 薬物代謝物の定量分析方法及び分析装置
WO2011073740A1 (en) 2009-12-15 2011-06-23 Centre National De La Recherche Scientifique (Cnrs) Matrices for mass spectrometry imaging
FR2973112B1 (fr) 2011-03-21 2018-05-25 Imabiotech Procede de detection et de quantification d'une molecule cible dans un echantillon
EP2767832A1 (en) 2013-02-18 2014-08-20 Imabiotech Photo or chemolabile conjugates for molecules detection
WO2014128309A1 (en) 2013-02-25 2014-08-28 Imabiotech Method to evaluate the tissue targeting of a molecule of interest

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BECKER J., et al., Phys. Status Solidi C, 2007, Vol. 4, Issue 6, pages 1775-1784 *
HARE D., et al., Metallomics, 2009, Issue 1, pages 53-58 *

Also Published As

Publication number Publication date
US10132796B2 (en) 2018-11-20
KR20140051187A (ko) 2014-04-30
JP6170911B2 (ja) 2017-07-26
ES2922478T3 (es) 2022-09-15
CN103688151B (zh) 2016-05-18
WO2012164221A1 (fr) 2012-12-06
AU2012264458A1 (en) 2014-01-09
US20140106391A1 (en) 2014-04-17
JP2014520259A (ja) 2014-08-21
EP2715310A1 (fr) 2014-04-09
IN2013MN02451A (OSRAM) 2015-04-17
FR2976076B1 (fr) 2015-02-27
FR2976076A1 (fr) 2012-12-07
KR102004350B1 (ko) 2019-07-26
CA2837153A1 (fr) 2012-12-06
EP2715310B1 (fr) 2022-04-27
CN103688151A (zh) 2014-03-26
DK2715310T3 (da) 2022-07-25
CA2837153C (fr) 2019-06-25

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