IN2013MN02451A - - Google Patents

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Publication number
IN2013MN02451A
IN2013MN02451A IN2451MUN2013A IN2013MN02451A IN 2013MN02451 A IN2013MN02451 A IN 2013MN02451A IN 2451MUN2013 A IN2451MUN2013 A IN 2451MUN2013A IN 2013MN02451 A IN2013MN02451 A IN 2013MN02451A
Authority
IN
India
Prior art keywords
tissue
standard
molecule
relates
range
Prior art date
Application number
Inventor
Jonathan Stauber
David Bonnel
Original Assignee
Imabiotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imabiotech filed Critical Imabiotech
Publication of IN2013MN02451A publication Critical patent/IN2013MN02451A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2866—Grinding or homogeneising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N2001/2893—Preparing calibration standards

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention relates to a method for preparing a range of dilutions of at least one standard molecule for a tissue according to which use is made of a ground tissue to which the standard molecule is added the whole being conditioned and fractionated before the analysis of a fraction of said tissue. The invention also relates to a method for detecting and quantifying at least one target molecule in at least one tissue using a standard range according to the invention.
IN2451MUN2013 2011-05-31 2012-05-29 IN2013MN02451A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1154731A FR2976076B1 (en) 2011-05-31 2011-05-31 METHOD FOR DETECTING AND QUANTIFYING TARGET MOLECULE IN TISSUE
PCT/FR2012/051205 WO2012164221A1 (en) 2011-05-31 2012-05-29 Method for detecting and quantifying a target molecule in a tissue

Publications (1)

Publication Number Publication Date
IN2013MN02451A true IN2013MN02451A (en) 2015-04-17

Family

ID=46420402

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2451MUN2013 IN2013MN02451A (en) 2011-05-31 2012-05-29

Country Status (12)

Country Link
US (1) US10132796B2 (en)
EP (1) EP2715310B1 (en)
JP (1) JP6170911B2 (en)
KR (1) KR102004350B1 (en)
CN (1) CN103688151B (en)
AU (1) AU2012264458B2 (en)
CA (1) CA2837153C (en)
DK (1) DK2715310T3 (en)
ES (1) ES2922478T3 (en)
FR (1) FR2976076B1 (en)
IN (1) IN2013MN02451A (en)
WO (1) WO2012164221A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2959294B1 (en) * 2013-02-25 2018-08-08 Imabiotech Method to evaluate the tissue targeting of a molecule of interest
CN103336128A (en) * 2013-06-08 2013-10-02 天津药物研究院 Detection method of tissue distribution of small molecule polypeptide drugs
BR112018009071B1 (en) * 2015-11-06 2021-12-14 Ventana Medical Systems, Inc IN VITRO METHOD TO PREPARE A REPRESENTATIVE SAMPLE FOR ANALYSIS
KR101996666B1 (en) * 2016-05-02 2019-07-04 주식회사 엘지화학 Method for quantitative analysis
CN112204388B (en) 2018-05-30 2023-07-18 株式会社岛津制作所 Spectral data processing device and analysis device
EP4111174A4 (en) * 2020-02-27 2024-03-27 Nicoya Lifesciences Inc Systems and methods for characterization of an assay from regions of interest using optical reactions
WO2021175842A1 (en) 2020-03-02 2021-09-10 Universiteit Maastricht Quality control standards for mass spectrometry imaging

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1230552B1 (en) * 1999-11-16 2006-01-11 Genentech, Inc. Elisa for vegf
EP1550862B1 (en) * 2002-10-04 2012-01-25 Protosera Inc. Method of identifying an analyte by gel electrophoresis-mass spectrometry
US20040096907A1 (en) * 2002-11-06 2004-05-20 Bernd Bohrmann Quantification of beta amyloid
JP2005181011A (en) * 2003-12-17 2005-07-07 Yoshio Yamauchi Method of analyzing protein
JP4547173B2 (en) 2004-03-17 2010-09-22 シスメックス株式会社 Diabetes care support system
WO2007000669A2 (en) 2005-06-07 2007-01-04 Centre National De La Recherche Scientifique (Cnrs) Use of conjugates with linkers cleavable by photodissociation or fragmentation for mass spectrometry analysis of tissue sections
EP2163900A1 (en) 2008-09-04 2010-03-17 Commissariat A L'energie Atomique New method of imaging by mass spectrometry and new mass tag associated trityl derivatives
JP4486166B2 (en) * 2008-10-08 2010-06-23 積水メディカル株式会社 Method and apparatus for quantitative analysis of drug metabolites
WO2011073740A1 (en) 2009-12-15 2011-06-23 Centre National De La Recherche Scientifique (Cnrs) Matrices for mass spectrometry imaging
FR2973112B1 (en) 2011-03-21 2018-05-25 Imabiotech METHOD FOR DETECTING AND QUANTIFYING TARGET MOLECULE IN A SAMPLE
EP2767832A1 (en) 2013-02-18 2014-08-20 Imabiotech Photo or chemolabile conjugates for molecules detection
EP2959294B1 (en) 2013-02-25 2018-08-08 Imabiotech Method to evaluate the tissue targeting of a molecule of interest

Also Published As

Publication number Publication date
AU2012264458A1 (en) 2014-01-09
FR2976076A1 (en) 2012-12-07
CA2837153A1 (en) 2012-12-06
ES2922478T3 (en) 2022-09-15
FR2976076B1 (en) 2015-02-27
KR20140051187A (en) 2014-04-30
DK2715310T3 (en) 2022-07-25
EP2715310B1 (en) 2022-04-27
US20140106391A1 (en) 2014-04-17
CN103688151B (en) 2016-05-18
US10132796B2 (en) 2018-11-20
EP2715310A1 (en) 2014-04-09
AU2012264458B2 (en) 2015-09-24
WO2012164221A1 (en) 2012-12-06
CN103688151A (en) 2014-03-26
CA2837153C (en) 2019-06-25
KR102004350B1 (en) 2019-07-26
JP6170911B2 (en) 2017-07-26
JP2014520259A (en) 2014-08-21

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