AU2012257630A1 - Process - Google Patents

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Info

Publication number
AU2012257630A1
AU2012257630A1 AU2012257630A AU2012257630A AU2012257630A1 AU 2012257630 A1 AU2012257630 A1 AU 2012257630A1 AU 2012257630 A AU2012257630 A AU 2012257630A AU 2012257630 A AU2012257630 A AU 2012257630A AU 2012257630 A1 AU2012257630 A1 AU 2012257630A1
Authority
AU
Australia
Prior art keywords
compound
formula
give
pharmaceutically acceptable
pct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2012257630A
Other languages
English (en)
Inventor
Neil Barnwell
Philip Cornwall
Duncan Michael Gill
Gareth P. Howell
Rebecca Elizabeth Meadows
Eric Merifield
Christopher William Mitchell
Andiappan Murugan
Philip O'keefe
Zakariya Mohamed Patel
James Barry Rose
John Singleton
Jane Withnall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2012257630A1 publication Critical patent/AU2012257630A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/07—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton
    • C07C309/08—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton containing hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/24—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/06—Oxalic acid
    • C07C55/07—Salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2012257630A 2011-05-13 2012-05-11 Process Abandoned AU2012257630A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1107985.2A GB201107985D0 (en) 2011-05-13 2011-05-13 Process
GB1107985.2 2011-05-13
PCT/GB2012/051037 WO2012156693A1 (en) 2011-05-13 2012-05-11 Process

Publications (1)

Publication Number Publication Date
AU2012257630A1 true AU2012257630A1 (en) 2013-11-28

Family

ID=44260448

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012257630A Abandoned AU2012257630A1 (en) 2011-05-13 2012-05-11 Process

Country Status (14)

Country Link
US (2) US20140364601A1 (enExample)
EP (1) EP2707362A1 (enExample)
JP (1) JP2014520075A (enExample)
KR (1) KR20140045380A (enExample)
CN (1) CN103649060A (enExample)
AU (1) AU2012257630A1 (enExample)
BR (1) BR112013028789A2 (enExample)
CA (1) CA2835237A1 (enExample)
GB (1) GB201107985D0 (enExample)
IL (1) IL229126A0 (enExample)
MX (1) MX2013012484A (enExample)
RU (1) RU2013148907A (enExample)
SG (1) SG194631A1 (enExample)
WO (1) WO2012156693A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3192B1 (ar) 2011-09-06 2018-03-08 Novartis Ag مركب بنزوثيازولون
CN103193658A (zh) * 2013-04-18 2013-07-10 苏州永健生物医药有限公司 一种（r）-2-对硝基苯乙胺基-1-苯乙醇及其盐的合成方法
TWI685497B (zh) 2014-06-02 2020-02-21 西班牙商伊史帝夫製藥公司 具有多重模式抗疼痛活性的１-氧雜-４,９-二氮雜螺十一烷化合物之烷基衍生物
TW201615642A (zh) * 2014-06-02 2016-05-01 伊史帝夫博士實驗室股份有限公司 具有多重模式抗疼痛活性的１－氧雜－４，９－二氮雜螺十一烷化合物之醯胺衍生物
TN2018000122A1 (en) 2015-11-16 2019-10-04 Esteve Labor Dr Oxadiazaspiro compounds for the treatment of drug abuse and addiction
FI3697795T3 (fi) 2017-10-17 2024-02-23 Acondicionamiento Tarrasense (R)-9-(2,5-difluorifenetyyli)-4-etyyli-2-metyyli-1-oksa-4,9-diatsaspiro[5.5]undekan-3-onin suoloja

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2185307T3 (es) 1998-02-02 2003-04-16 Lg Chemical Ltd Inhibidores de la farnesil transferasa que tienen una estructura piperidinica y procedimiento para su preparacion.
AR040962A1 (es) 2002-08-09 2005-04-27 Novartis Ag Compuestos derivados de tiazol 1,3-2-ona, composicion farmaceutica y proceso de preparacion del compuesto
GB0218629D0 (en) * 2002-08-09 2002-09-18 Novartis Ag Organic compounds
TW200738659A (en) * 2005-08-29 2007-10-16 Astrazeneca Ab Novel compounds
CN101300239A (zh) * 2005-08-29 2008-11-05 阿斯利康(瑞典)有限公司 作为β2肾上腺素受体激动剂的7-（2-氨基-1-羟基-乙基）-4-羟基苯并噻唑-2(3H)-酮衍生物
CN102083839B (zh) * 2008-02-06 2014-03-26 阿斯利康(瑞典)有限公司 化合物

Also Published As

Publication number Publication date
BR112013028789A2 (pt) 2016-08-09
US20140364601A1 (en) 2014-12-11
MX2013012484A (es) 2014-01-24
EP2707362A1 (en) 2014-03-19
GB201107985D0 (en) 2011-06-29
US20160002261A1 (en) 2016-01-07
KR20140045380A (ko) 2014-04-16
WO2012156693A1 (en) 2012-11-22
SG194631A1 (en) 2013-12-30
RU2013148907A (ru) 2015-06-20
JP2014520075A (ja) 2014-08-21
IL229126A0 (en) 2013-12-31
CN103649060A (zh) 2014-03-19
CA2835237A1 (en) 2012-11-22

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted