AU2012255066B2 - Modification-dependent activity assays - Google Patents

Modification-dependent activity assays Download PDF

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Publication number
AU2012255066B2
AU2012255066B2 AU2012255066A AU2012255066A AU2012255066B2 AU 2012255066 B2 AU2012255066 B2 AU 2012255066B2 AU 2012255066 A AU2012255066 A AU 2012255066A AU 2012255066 A AU2012255066 A AU 2012255066A AU 2012255066 B2 AU2012255066 B2 AU 2012255066B2
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AU
Australia
Prior art keywords
factor
antibody
recombinant
polypeptide
modification
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AU2012255066A
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AU2012255066A1 (en
Inventor
Andrea ENGELMAIER
Hans Peter Schwarz
Alfred Weber
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of AU2012255066A1 publication Critical patent/AU2012255066A1/en
Assigned to BAXTER HEALTHCARE SA, BAXTER INTERNATIONAL INC. reassignment BAXTER HEALTHCARE SA Amend patent request/document other than specification (104) Assignors: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL, INC.
Assigned to Baxalta GmbH, BAXALTA INCORPORATED reassignment Baxalta GmbH Request for Assignment Assignors: BAXTER HEALTHCARE SA, BAXTER INTERNATIONAL INC.
Priority to AU2016203387A priority Critical patent/AU2016203387B2/en
Application granted granted Critical
Publication of AU2012255066B2 publication Critical patent/AU2012255066B2/en
Assigned to TAKEDA PHARMACEUTICAL COMPANY LIMITED reassignment TAKEDA PHARMACEUTICAL COMPANY LIMITED Request for Assignment Assignors: Baxalta GmbH, BAXALTA INCORPORATED
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00Post-translational modifications [PTMs] in chemical analysis of biological material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2012255066A 2011-05-18 2012-05-18 Modification-dependent activity assays Active AU2012255066B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2016203387A AU2016203387B2 (en) 2011-05-18 2016-05-24 Modification-Dependent Activity Assays

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161487612P 2011-05-18 2011-05-18
US61/487,612 2011-05-18
PCT/US2012/038704 WO2012159084A1 (en) 2011-05-18 2012-05-18 Modification-dependent activity assays

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016203387A Division AU2016203387B2 (en) 2011-05-18 2016-05-24 Modification-Dependent Activity Assays

Publications (2)

Publication Number Publication Date
AU2012255066A1 AU2012255066A1 (en) 2013-05-02
AU2012255066B2 true AU2012255066B2 (en) 2016-06-02

Family

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Application Number Title Priority Date Filing Date
AU2012255066A Active AU2012255066B2 (en) 2011-05-18 2012-05-18 Modification-dependent activity assays
AU2016203387A Active AU2016203387B2 (en) 2011-05-18 2016-05-24 Modification-Dependent Activity Assays

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2016203387A Active AU2016203387B2 (en) 2011-05-18 2016-05-24 Modification-Dependent Activity Assays

Country Status (11)

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US (1) US8785139B2 (enExample)
EP (3) EP3943939A1 (enExample)
JP (5) JP6175426B2 (enExample)
AU (2) AU2012255066B2 (enExample)
CA (1) CA2836103C (enExample)
DK (2) DK2710375T3 (enExample)
ES (2) ES2720138T3 (enExample)
PL (2) PL3517956T3 (enExample)
PT (2) PT2710375T (enExample)
TR (1) TR201904997T4 (enExample)
WO (1) WO2012159084A1 (enExample)

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CN102375055A (zh) * 2010-08-19 2012-03-14 中国人民解放军军事医学科学院微生物流行病研究所 一种多重检测免疫层析芯片
US10745737B2 (en) * 2012-11-09 2020-08-18 Children's Medical Center Corporation Methods and reagents for glycoproteomics
CN103819907B (zh) * 2014-03-10 2016-04-06 山东理工大学 一种用聚丙二醇与聚乙烯醇对聚肽膜亲水性进行改进的方法
WO2015169602A1 (en) * 2014-05-05 2015-11-12 Noviosmart Method for the serological diagnosis of rheumatoid arthritis.
CN104559207B (zh) * 2015-01-05 2017-02-22 山东理工大学 一种聚氨基甲酸酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104559206B (zh) * 2015-01-05 2017-02-22 山东理工大学 一种聚三亚甲基碳酸酯与聚丙烯酰胺改进聚肽膜亲水性与柔顺性的方法
CN104448841B (zh) * 2015-01-06 2016-08-31 山东理工大学 一种聚乳酸乙醇酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104448843B (zh) * 2015-01-06 2016-10-05 山东理工大学 一种聚己内酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104448842B (zh) * 2015-01-06 2016-08-31 山东理工大学 一种聚乳酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104559224B (zh) * 2015-01-12 2017-02-22 山东理工大学 一种聚丙二醇与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法
CN104530722B (zh) * 2015-01-12 2017-05-03 山东理工大学 一种聚乳酸乙醇酸与羧甲基壳聚糖改进聚肽膜亲水性与柔顺性的方法
CN104479367B (zh) * 2015-01-12 2016-08-31 山东理工大学 一种聚乳酸与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法
US9804170B2 (en) 2015-02-09 2017-10-31 Bristol-Myers Squibb Company Antibodies to polyethylene glycol
JP6552286B2 (ja) * 2015-06-05 2019-07-31 公立大学法人奈良県立医科大学 凝固第viii因子の複合体形成能に関する情報の取得方法および試薬キット
SG11202107497XA (en) 2019-01-23 2021-08-30 Regeneron Pharma Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors
US11845989B2 (en) 2019-01-23 2023-12-19 Regeneron Pharmaceuticals, Inc. Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors
CN110118847B (zh) * 2019-05-17 2021-08-10 重庆派金生物科技有限公司 确定多位点peg修饰蛋白质修饰位点的分析方法
EP4298219A1 (en) 2021-02-26 2024-01-03 Regeneron Pharmaceuticals, Inc. Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (angptl7) inhibitors
WO2023021311A1 (en) * 2021-08-20 2023-02-23 Takeda Pharmaceutical Company Limited Selective measurement of human factor viii
CA3244889A1 (en) 2022-03-08 2023-09-14 Equashield Medical Ltd FLUID TRANSFER STATION IN A ROBOTIC PHARMACEUTICAL PREPARATION SYSTEM

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Also Published As

Publication number Publication date
CA2836103C (en) 2020-07-14
JP6863950B2 (ja) 2021-04-21
US20120329072A1 (en) 2012-12-27
PT2710375T (pt) 2019-05-08
PL2710375T3 (pl) 2019-07-31
WO2012159084A1 (en) 2012-11-22
TR201904997T4 (tr) 2019-05-21
DK3517956T3 (da) 2021-10-11
JP2023081972A (ja) 2023-06-13
PL3517956T3 (pl) 2021-12-20
ES2893605T3 (es) 2022-02-09
JP7618714B2 (ja) 2025-01-21
JP7242627B2 (ja) 2023-03-20
US8785139B2 (en) 2014-07-22
ES2720138T3 (es) 2019-07-18
EP3943939A1 (en) 2022-01-26
JP2019035765A (ja) 2019-03-07
DK2710375T3 (en) 2019-04-29
PT3517956T (pt) 2021-10-15
EP2710375A1 (en) 2014-03-26
EP3517956A1 (en) 2019-07-31
AU2012255066A1 (en) 2013-05-02
JP2021063816A (ja) 2021-04-22
JP6175426B2 (ja) 2017-08-02
CA2836103A1 (en) 2012-11-22
JP2014524010A (ja) 2014-09-18
JP2017161536A (ja) 2017-09-14
EP3517956B1 (en) 2021-09-08
AU2016203387A1 (en) 2016-06-16
AU2016203387B2 (en) 2018-01-25
EP2710375B1 (en) 2019-03-13

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: BAXALTA GMBH; BAXALTA INCORPORATED

Free format text: FORMER APPLICANT(S): BAXTER HEALTHCARE SA; BAXTER INTERNATIONAL INC.

FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Free format text: FORMER OWNER(S): BAXALTA INCORPORATED; BAXALTA GMBH