JP2014524010A5 - - Google Patents

Download PDF

Info

Publication number
JP2014524010A5
JP2014524010A5 JP2014511600A JP2014511600A JP2014524010A5 JP 2014524010 A5 JP2014524010 A5 JP 2014524010A5 JP 2014511600 A JP2014511600 A JP 2014511600A JP 2014511600 A JP2014511600 A JP 2014511600A JP 2014524010 A5 JP2014524010 A5 JP 2014524010A5
Authority
JP
Japan
Prior art keywords
factor
antibody
recombinant
group
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014511600A
Other languages
English (en)
Japanese (ja)
Other versions
JP6175426B2 (ja
JP2014524010A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/038704 external-priority patent/WO2012159084A1/en
Publication of JP2014524010A publication Critical patent/JP2014524010A/ja
Publication of JP2014524010A5 publication Critical patent/JP2014524010A5/ja
Application granted granted Critical
Publication of JP6175426B2 publication Critical patent/JP6175426B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014511600A 2011-05-18 2012-05-18 修飾依存的活性アッセイ Active JP6175426B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161487612P 2011-05-18 2011-05-18
US61/487,612 2011-05-18
PCT/US2012/038704 WO2012159084A1 (en) 2011-05-18 2012-05-18 Modification-dependent activity assays

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017079848A Division JP2017161536A (ja) 2011-05-18 2017-04-13 修飾依存的活性アッセイ

Publications (3)

Publication Number Publication Date
JP2014524010A JP2014524010A (ja) 2014-09-18
JP2014524010A5 true JP2014524010A5 (enExample) 2015-07-02
JP6175426B2 JP6175426B2 (ja) 2017-08-02

Family

ID=46208807

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2014511600A Active JP6175426B2 (ja) 2011-05-18 2012-05-18 修飾依存的活性アッセイ
JP2017079848A Pending JP2017161536A (ja) 2011-05-18 2017-04-13 修飾依存的活性アッセイ
JP2018210141A Active JP6863950B2 (ja) 2011-05-18 2018-11-08 修飾依存的活性アッセイ
JP2020208021A Active JP7242627B2 (ja) 2011-05-18 2020-12-16 修飾依存的活性アッセイ
JP2023035124A Active JP7618714B2 (ja) 2011-05-18 2023-03-08 修飾依存的活性アッセイ

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2017079848A Pending JP2017161536A (ja) 2011-05-18 2017-04-13 修飾依存的活性アッセイ
JP2018210141A Active JP6863950B2 (ja) 2011-05-18 2018-11-08 修飾依存的活性アッセイ
JP2020208021A Active JP7242627B2 (ja) 2011-05-18 2020-12-16 修飾依存的活性アッセイ
JP2023035124A Active JP7618714B2 (ja) 2011-05-18 2023-03-08 修飾依存的活性アッセイ

Country Status (11)

Country Link
US (1) US8785139B2 (enExample)
EP (3) EP3943939A1 (enExample)
JP (5) JP6175426B2 (enExample)
AU (2) AU2012255066B2 (enExample)
CA (1) CA2836103C (enExample)
DK (2) DK2710375T3 (enExample)
ES (2) ES2720138T3 (enExample)
PL (2) PL3517956T3 (enExample)
PT (2) PT2710375T (enExample)
TR (1) TR201904997T4 (enExample)
WO (1) WO2012159084A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102375055A (zh) * 2010-08-19 2012-03-14 中国人民解放军军事医学科学院微生物流行病研究所 一种多重检测免疫层析芯片
US10745737B2 (en) * 2012-11-09 2020-08-18 Children's Medical Center Corporation Methods and reagents for glycoproteomics
CN103819907B (zh) * 2014-03-10 2016-04-06 山东理工大学 一种用聚丙二醇与聚乙烯醇对聚肽膜亲水性进行改进的方法
WO2015169602A1 (en) * 2014-05-05 2015-11-12 Noviosmart Method for the serological diagnosis of rheumatoid arthritis.
CN104559207B (zh) * 2015-01-05 2017-02-22 山东理工大学 一种聚氨基甲酸酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104559206B (zh) * 2015-01-05 2017-02-22 山东理工大学 一种聚三亚甲基碳酸酯与聚丙烯酰胺改进聚肽膜亲水性与柔顺性的方法
CN104448841B (zh) * 2015-01-06 2016-08-31 山东理工大学 一种聚乳酸乙醇酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104448843B (zh) * 2015-01-06 2016-10-05 山东理工大学 一种聚己内酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104448842B (zh) * 2015-01-06 2016-08-31 山东理工大学 一种聚乳酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104559224B (zh) * 2015-01-12 2017-02-22 山东理工大学 一种聚丙二醇与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法
CN104530722B (zh) * 2015-01-12 2017-05-03 山东理工大学 一种聚乳酸乙醇酸与羧甲基壳聚糖改进聚肽膜亲水性与柔顺性的方法
CN104479367B (zh) * 2015-01-12 2016-08-31 山东理工大学 一种聚乳酸与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法
US9804170B2 (en) 2015-02-09 2017-10-31 Bristol-Myers Squibb Company Antibodies to polyethylene glycol
JP6552286B2 (ja) * 2015-06-05 2019-07-31 公立大学法人奈良県立医科大学 凝固第viii因子の複合体形成能に関する情報の取得方法および試薬キット
SG11202107497XA (en) 2019-01-23 2021-08-30 Regeneron Pharma Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors
US11845989B2 (en) 2019-01-23 2023-12-19 Regeneron Pharmaceuticals, Inc. Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors
CN110118847B (zh) * 2019-05-17 2021-08-10 重庆派金生物科技有限公司 确定多位点peg修饰蛋白质修饰位点的分析方法
EP4298219A1 (en) 2021-02-26 2024-01-03 Regeneron Pharmaceuticals, Inc. Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (angptl7) inhibitors
WO2023021311A1 (en) * 2021-08-20 2023-02-23 Takeda Pharmaceutical Company Limited Selective measurement of human factor viii
CA3244889A1 (en) 2022-03-08 2023-09-14 Equashield Medical Ltd FLUID TRANSFER STATION IN A ROBOTIC PHARMACEUTICAL PREPARATION SYSTEM

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3244030A1 (de) 1982-11-27 1984-05-30 Behringwerke Ag, 3550 Marburg Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung
US5208148A (en) 1990-12-07 1993-05-04 Molecular Probes, Inc. Lipophilic fluorescent glycosidase substrates
EP0603266B1 (en) 1991-08-23 1999-05-12 Molecular Probes, Inc. Use of haloalkyl derivatives of reporter molecules to analyze metabolic activity in cells
US5576424A (en) 1991-08-23 1996-11-19 Molecular Probes, Inc. Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells
US5242805A (en) 1991-08-23 1993-09-07 Molecular Probes, Inc. Long wavelength lipophilic fluorogenic glycosidase substrates
US5830912A (en) 1996-11-15 1998-11-03 Molecular Probes, Inc. Derivatives of 6,8-difluoro-7-hydroxycoumarin
US5773236A (en) 1997-04-25 1998-06-30 Molecule Probes, Inc. Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules
CN1688248A (zh) * 2002-08-22 2005-10-26 贝克顿·迪金森公司 痴呆相关神经疾病的诊断方法
US8133865B2 (en) 2006-12-27 2012-03-13 Nektar Therapeutics von Willebrand factor- and factor VIII-polymer conjugates having a releasable linkage
US9333247B2 (en) * 2007-07-03 2016-05-10 Children's Hospital & Research Center At Oakland Oligosialic acid derivatives, methods of manufacture, and immunological uses
ES2587742T3 (es) * 2007-12-27 2016-10-26 Baxalta GmbH Métodos para diferenciar en una muestra proteína derivada de plasma de proteína recombinante
ES2515365T3 (es) * 2007-12-27 2014-10-29 Baxter International Inc. Procedimiento y composiciones para detectar específicamente moléculas poliméricas fisiológicamente aceptables
BRPI0911266A2 (pt) * 2008-04-03 2015-09-29 Hoffmann La Roche ensaio de fator de crescimento similar à insulina peguilado
CA2740904C (en) * 2008-10-21 2019-01-15 Baxter International Inc. Methods for determining active ingredients in pro-drug peg protein conjugates with releasable peg reagents (in vitro de-pegylation)
US8642737B2 (en) 2010-07-26 2014-02-04 Baxter International Inc. Nucleophilic catalysts for oxime linkage
EP3081233B1 (en) 2009-07-27 2020-12-23 Baxalta GmbH Glycopolysialylation of proteins other than blood coagulation proteins
AU2010281453C1 (en) 2009-07-27 2019-08-15 Takeda Pharmaceutical Company Limited Blood coagulation protein conjugates
GB2488532B (en) * 2011-02-18 2013-06-05 Sca Ipla Holdings Inc Communication units and methods for control change notification in broadcast communication

Similar Documents

Publication Publication Date Title
JP2014524010A5 (enExample)
JP7618714B2 (ja) 修飾依存的活性アッセイ
Firestein et al. Quantitative analysis of cytokine gene expression in rheumatoid arthritis.
Lathrop et al. Therapeutic potential of the plasma proteome
CA2642648C (en) Detection of anthrax pathogenicity factors
RU2522231C1 (ru) Способ диагностики онкологических заболеваний и иммуноферментный набор для его осуществления
DE50014975D1 (de) Verfahren zur Reindarstellung des Proenzyms der den Blutgerinnungsfaktor VII aktivierenden Protease mittels Ionenaustauscherchromatographie
JP2006507004A (ja) プロテアーゼ酵素の検出
Ohnishi et al. Development of highly sensitive enzyme-linked immunosorbent assays for hepatocyte growth factor/scatter factor (HGF/SF): determination of HGF/SF in serum and urine from normal human subjects
JP2021523378A (ja) タンパク質の定量分析
James et al. The effect of α2 macroglobulin in commercial cytokine assays
CN119375379A (zh) 一种基于lc-ms/ms的相思子毒素活性的检测方法
EP1504265B1 (en) Sandwich assay
WO2014007242A1 (ja) Hb-egfの測定方法
Proost et al. Posttranslational processing of chemokines
JPS6113156A (ja) ヒトインタ−フエロン−αの定量用試薬及び定量法
WO2005114196A1 (ja) 間質性膀胱炎の検査方法
HK40067577A (en) Modification-dependent activity assays
HK40010723B (en) Modification-dependent activity assays
HK40010723A (en) Modification-dependent activity assays