TR201904997T4 - Modifikasyona bağlı aktivite tahlilleri. - Google Patents

Modifikasyona bağlı aktivite tahlilleri. Download PDF

Info

Publication number
TR201904997T4
TR201904997T4 TR2019/04997T TR201904997T TR201904997T4 TR 201904997 T4 TR201904997 T4 TR 201904997T4 TR 2019/04997 T TR2019/04997 T TR 2019/04997T TR 201904997 T TR201904997 T TR 201904997T TR 201904997 T4 TR201904997 T4 TR 201904997T4
Authority
TR
Turkey
Prior art keywords
modification
activity assays
assays due
activity
kits
Prior art date
Application number
TR2019/04997T
Other languages
English (en)
Inventor
Weber Alfred
Engelmaier Andrea
Peter Schwarz Hans
Original Assignee
Baxalta GmbH
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta GmbH, Baxalta Inc filed Critical Baxalta GmbH
Publication of TR201904997T4 publication Critical patent/TR201904997T4/tr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material

Abstract

Bir modifikasyon içeren rekombinant polipeptitlerin mevcudiyetinin ve/veya aktivitesinin ölçülmesine yönelik yöntemler, sistemler ve kitler burada açıklanmaktadır.
TR2019/04997T 2011-05-18 2012-05-18 Modifikasyona bağlı aktivite tahlilleri. TR201904997T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161487612P 2011-05-18 2011-05-18

Publications (1)

Publication Number Publication Date
TR201904997T4 true TR201904997T4 (tr) 2019-05-21

Family

ID=46208807

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/04997T TR201904997T4 (tr) 2011-05-18 2012-05-18 Modifikasyona bağlı aktivite tahlilleri.

Country Status (11)

Country Link
US (1) US8785139B2 (tr)
EP (3) EP2710375B1 (tr)
JP (5) JP6175426B2 (tr)
AU (2) AU2012255066B2 (tr)
CA (1) CA2836103C (tr)
DK (2) DK3517956T3 (tr)
ES (2) ES2720138T3 (tr)
PL (2) PL3517956T3 (tr)
PT (2) PT2710375T (tr)
TR (1) TR201904997T4 (tr)
WO (1) WO2012159084A1 (tr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102375055A (zh) * 2010-08-19 2012-03-14 中国人民解放军军事医学科学院微生物流行病研究所 一种多重检测免疫层析芯片
US10745737B2 (en) * 2012-11-09 2020-08-18 Children's Medical Center Corporation Methods and reagents for glycoproteomics
CN103819907B (zh) * 2014-03-10 2016-04-06 山东理工大学 一种用聚丙二醇与聚乙烯醇对聚肽膜亲水性进行改进的方法
JP6543332B2 (ja) * 2014-05-05 2019-07-10 ノヴィオ テーハー ベー．フェー．Ｎｏｖｉｏ ＴＨ Ｂ．Ｖ． 関節リウマチの血清学的な診断方法
CN104559206B (zh) * 2015-01-05 2017-02-22 山东理工大学 一种聚三亚甲基碳酸酯与聚丙烯酰胺改进聚肽膜亲水性与柔顺性的方法
CN104559207B (zh) * 2015-01-05 2017-02-22 山东理工大学 一种聚氨基甲酸酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104448842B (zh) * 2015-01-06 2016-08-31 山东理工大学 一种聚乳酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104448843B (zh) * 2015-01-06 2016-10-05 山东理工大学 一种聚己内酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104448841B (zh) * 2015-01-06 2016-08-31 山东理工大学 一种聚乳酸乙醇酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法
CN104559224B (zh) * 2015-01-12 2017-02-22 山东理工大学 一种聚丙二醇与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法
CN104530722B (zh) * 2015-01-12 2017-05-03 山东理工大学 一种聚乳酸乙醇酸与羧甲基壳聚糖改进聚肽膜亲水性与柔顺性的方法
CN104479367B (zh) * 2015-01-12 2016-08-31 山东理工大学 一种聚乳酸与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法
US9804170B2 (en) 2015-02-09 2017-10-31 Bristol-Myers Squibb Company Antibodies to polyethylene glycol
JP6552286B2 (ja) * 2015-06-05 2019-07-31 公立大学法人奈良県立医科大学 凝固第ｖｉｉｉ因子の複合体形成能に関する情報の取得方法および試薬キット
US11845989B2 (en) 2019-01-23 2023-12-19 Regeneron Pharmaceuticals, Inc. Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors
US11767526B2 (en) 2019-01-23 2023-09-26 Regeneron Pharmaceuticals, Inc. Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors
CN110118847B (zh) * 2019-05-17 2021-08-10 重庆派金生物科技有限公司 确定多位点peg修饰蛋白质修饰位点的分析方法
AU2022226164A1 (en) 2021-02-26 2023-08-03 Regeneron Pharmaceuticals, Inc. Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (angptl7) inhibitors
CN117836425A (zh) * 2021-08-20 2024-04-05 武田药品工业株式会社 人因子viii的选择性测量
WO2023170680A1 (en) 2022-03-08 2023-09-14 Equashield Medical Ltd Fluid transfer station in a robotic pharmaceutical preparation system

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3244030A1 (de) 1982-11-27 1984-05-30 Behringwerke Ag, 3550 Marburg Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung
US5208148A (en) 1990-12-07 1993-05-04 Molecular Probes, Inc. Lipophilic fluorescent glycosidase substrates
US5576424A (en) 1991-08-23 1996-11-19 Molecular Probes, Inc. Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells
US5242805A (en) 1991-08-23 1993-09-07 Molecular Probes, Inc. Long wavelength lipophilic fluorogenic glycosidase substrates
ATE180018T1 (de) 1991-08-23 1999-05-15 Molecular Probes Inc Verwendung von haloalkylderivaten von reportermolekülen zur analyse der metabolischen aktivität in zellen
US5830912A (en) 1996-11-15 1998-11-03 Molecular Probes, Inc. Derivatives of 6,8-difluoro-7-hydroxycoumarin
US5773236A (en) 1997-04-25 1998-06-30 Molecule Probes, Inc. Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules
AU2003262774A1 (en) * 2002-08-22 2004-03-11 Becton, Dickinson And Company Methods for diagnosing dementia-related neurological disorders
CA2690440A1 (en) * 2007-07-03 2009-01-08 Children's Hospital & Research Center At Oakland Oligosialic acid derivatives, methods of manufacture, and immunological uses
EP2245456B1 (en) * 2007-12-27 2013-02-13 Baxter International Inc. Method and compositions for specifically detecting physiologically acceptable polymer molecules
DK2223108T3 (en) * 2007-12-27 2016-07-18 Baxalta GmbH Methods for differentiation of plasma-derived protein from the recombinant protein in a sample
CA2720478A1 (en) * 2008-04-03 2009-10-08 F. Hoffmann-La Roche Ag Pegylated insulin-like-growth-factor assay
WO2010048184A2 (en) * 2008-10-21 2010-04-29 Baxter International Inc. Methods for determining active ingredients in pro-drug peg protein conjugates with releasable peg reagents (in vitro de-pegylation)
ES2597954T3 (es) 2009-07-27 2017-01-24 Baxalta GmbH Conjugados de proteína de la coagulación sanguínea
US8642737B2 (en) 2010-07-26 2014-02-04 Baxter International Inc. Nucleophilic catalysts for oxime linkage
EP2459226B1 (en) 2009-07-27 2016-06-29 Lipoxen Technologies Limited Glycopolysialylation of proteins other than blood coagulation proteins
GB2488532B (en) * 2011-02-18 2013-06-05 Sca Ipla Holdings Inc Communication units and methods for control change notification in broadcast communication

Also Published As

Publication number Publication date
CA2836103C (en) 2020-07-14
AU2012255066A1 (en) 2013-05-02
JP6175426B2 (ja) 2017-08-02
US20120329072A1 (en) 2012-12-27
EP3943939A1 (en) 2022-01-26
AU2016203387B2 (en) 2018-01-25
DK2710375T3 (en) 2019-04-29
JP6863950B2 (ja) 2021-04-21
US8785139B2 (en) 2014-07-22
AU2012255066B2 (en) 2016-06-02
PT2710375T (pt) 2019-05-08
EP2710375A1 (en) 2014-03-26
AU2016203387A1 (en) 2016-06-16
PL2710375T3 (pl) 2019-07-31
JP2019035765A (ja) 2019-03-07
DK3517956T3 (da) 2021-10-11
JP2021063816A (ja) 2021-04-22
ES2893605T3 (es) 2022-02-09
WO2012159084A1 (en) 2012-11-22
JP2023081972A (ja) 2023-06-13
ES2720138T3 (es) 2019-07-18
PL3517956T3 (pl) 2021-12-20
EP3517956A1 (en) 2019-07-31
PT3517956T (pt) 2021-10-15
JP7242627B2 (ja) 2023-03-20
JP2014524010A (ja) 2014-09-18
EP3517956B1 (en) 2021-09-08
JP2017161536A (ja) 2017-09-14
EP2710375B1 (en) 2019-03-13
CA2836103A1 (en) 2012-11-22

Similar Documents

Publication Publication Date Title
TR201904997T4 (tr) Modifikasyona bağlı aktivite tahlilleri.
CL2016000460A1 (es) Proteínas de unión al antígeno gitr
NI201500103A (es) Anticuerpos cd47 que no agotan plaquetas ni glóbulos rojos y métodos de uso de los mismos.
MY170983A (en) Biomarker assays for detecting or measuring inhibition of tor kinase activity
UY34317A (es) Anticuerpo antireceptor de célula T (alfa)/ß
CO7061035A2 (es) Péptido de tránsito al cloroplasto
MA38632B1 (fr) Anticorps anti-récepteur de transferrine et procédés d'utilisation
BR112014019331A8 (pt) anticorpos para cd47 e métodos de uso desses
UY34394A (es) Polipéptidos de anticuerpos que antagonizan cd40l
UY34456A (es) Anticuerpos anti-il-36r
UY34206A (es) Anticuerpo monoclonal de interleucina-31
CL2012002979A1 (es) Derivados de n3-sustituido-n1-sulfonil-5-fluorpirimidinona.
UY34343A (es) Proteinas de unión al antígeno cd27l
AR093446A1 (es) Anticuerpos de antihemaglutinina y metodos de uso
UY34527A (es) ?composiciones, métodos y kits para la preparación de proteínas recombinantes sialiladas?.
UY4153Q (es) Batería
BR112013028251A2 (pt) polipeptídeo
TR201819828T4 (tr) Anti-fosfolipaz d4 antikoru.
TR201910464T4 (tr) Bir fermuara yönelik durdurucu ve bunun üretimine ilişkin bir yöntem.
MY165647A (en) Psa assay and reagent therefor
UY34483A (es) Polipeptido
EA201491034A1 (ru) Экспрессионная кассета
UY4152Q (es) Batería
CL2012001192S1 (es) Botella.
TR201105829U (tr) Küçük otobüsler için özel bir klima cihazı teritbatı.