PT3517956T - Ensaios de atividade dependente de modificação - Google Patents
Ensaios de atividade dependente de modificaçãoInfo
- Publication number
- PT3517956T PT3517956T PT191610021T PT19161002T PT3517956T PT 3517956 T PT3517956 T PT 3517956T PT 191610021 T PT191610021 T PT 191610021T PT 19161002 T PT19161002 T PT 19161002T PT 3517956 T PT3517956 T PT 3517956T
- Authority
- PT
- Portugal
- Prior art keywords
- modification
- activity assays
- dependent activity
- dependent
- assays
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161487612P | 2011-05-18 | 2011-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3517956T true PT3517956T (pt) | 2021-10-15 |
Family
ID=46208807
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT12725954T PT2710375T (pt) | 2011-05-18 | 2012-05-18 | Ensaios de atividade dependente de modificação |
| PT191610021T PT3517956T (pt) | 2011-05-18 | 2012-05-18 | Ensaios de atividade dependente de modificação |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT12725954T PT2710375T (pt) | 2011-05-18 | 2012-05-18 | Ensaios de atividade dependente de modificação |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8785139B2 (pt) |
| EP (3) | EP3517956B1 (pt) |
| JP (5) | JP6175426B2 (pt) |
| AU (2) | AU2012255066B2 (pt) |
| CA (1) | CA2836103C (pt) |
| DK (2) | DK2710375T3 (pt) |
| ES (2) | ES2720138T3 (pt) |
| PL (2) | PL3517956T3 (pt) |
| PT (2) | PT2710375T (pt) |
| TR (1) | TR201904997T4 (pt) |
| WO (1) | WO2012159084A1 (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102375055A (zh) * | 2010-08-19 | 2012-03-14 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种多重检测免疫层析芯片 |
| US10745737B2 (en) * | 2012-11-09 | 2020-08-18 | Children's Medical Center Corporation | Methods and reagents for glycoproteomics |
| CN103819907B (zh) * | 2014-03-10 | 2016-04-06 | 山东理工大学 | 一种用聚丙二醇与聚乙烯醇对聚肽膜亲水性进行改进的方法 |
| JP6543332B2 (ja) * | 2014-05-05 | 2019-07-10 | ノヴィオ テーハー ベー．フェー．Ｎｏｖｉｏ ＴＨ Ｂ．Ｖ． | 関節リウマチの血清学的な診断方法 |
| CN104559207B (zh) * | 2015-01-05 | 2017-02-22 | 山东理工大学 | 一种聚氨基甲酸酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法 |
| CN104559206B (zh) * | 2015-01-05 | 2017-02-22 | 山东理工大学 | 一种聚三亚甲基碳酸酯与聚丙烯酰胺改进聚肽膜亲水性与柔顺性的方法 |
| CN104448842B (zh) * | 2015-01-06 | 2016-08-31 | 山东理工大学 | 一种聚乳酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法 |
| CN104448841B (zh) * | 2015-01-06 | 2016-08-31 | 山东理工大学 | 一种聚乳酸乙醇酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法 |
| CN104448843B (zh) * | 2015-01-06 | 2016-10-05 | 山东理工大学 | 一种聚己内酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法 |
| CN104479367B (zh) * | 2015-01-12 | 2016-08-31 | 山东理工大学 | 一种聚乳酸与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法 |
| CN104559224B (zh) * | 2015-01-12 | 2017-02-22 | 山东理工大学 | 一种聚丙二醇与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法 |
| CN104530722B (zh) * | 2015-01-12 | 2017-05-03 | 山东理工大学 | 一种聚乳酸乙醇酸与羧甲基壳聚糖改进聚肽膜亲水性与柔顺性的方法 |
| US9804170B2 (en) | 2015-02-09 | 2017-10-31 | Bristol-Myers Squibb Company | Antibodies to polyethylene glycol |
| JP6552286B2 (ja) * | 2015-06-05 | 2019-07-31 | 公立大学法人奈良県立医科大学 | 凝固第ｖｉｉｉ因子の複合体形成能に関する情報の取得方法および試薬キット |
| US11845989B2 (en) | 2019-01-23 | 2023-12-19 | Regeneron Pharmaceuticals, Inc. | Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors |
| MX2021008797A (es) | 2019-01-23 | 2022-01-31 | Regeneron Pharma | Tratamiento de afecciones oftalmicas con inhibidores de proteinas relacionadas a angiopoyetina 7 (angptl7). |
| CN110118847B (zh) * | 2019-05-17 | 2021-08-10 | 重庆派金生物科技有限公司 | 确定多位点peg修饰蛋白质修饰位点的分析方法 |
| US11865134B2 (en) | 2021-02-26 | 2024-01-09 | Regeneron Pharmaceuticals, Inc. | Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (ANGPTL7) inhibitors |
| EP4388124A1 (en) * | 2021-08-20 | 2024-06-26 | Takeda Pharmaceutical Company Limited | Selective measurement of human factor viii |
| AU2023232562A1 (en) | 2022-03-08 | 2024-09-05 | Equashield Medical Ltd | Fluid transfer station in a robotic pharmaceutical preparation system |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3244030A1 (de) | 1982-11-27 | 1984-05-30 | Behringwerke Ag, 3550 Marburg | Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung |
| US5208148A (en) | 1990-12-07 | 1993-05-04 | Molecular Probes, Inc. | Lipophilic fluorescent glycosidase substrates |
| US5576424A (en) | 1991-08-23 | 1996-11-19 | Molecular Probes, Inc. | Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells |
| ATE180018T1 (de) | 1991-08-23 | 1999-05-15 | Molecular Probes Inc | Verwendung von haloalkylderivaten von reportermolekülen zur analyse der metabolischen aktivität in zellen |
| US5242805A (en) | 1991-08-23 | 1993-09-07 | Molecular Probes, Inc. | Long wavelength lipophilic fluorogenic glycosidase substrates |
| US5830912A (en) | 1996-11-15 | 1998-11-03 | Molecular Probes, Inc. | Derivatives of 6,8-difluoro-7-hydroxycoumarin |
| US5773236A (en) | 1997-04-25 | 1998-06-30 | Molecule Probes, Inc. | Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules |
| CN1688248A (zh) * | 2002-08-22 | 2005-10-26 | 贝克顿·迪金森公司 | 痴呆相关神经疾病的诊断方法 |
| CA2690440A1 (en) * | 2007-07-03 | 2009-01-08 | Children's Hospital & Research Center At Oakland | Oligosialic acid derivatives, methods of manufacture, and immunological uses |
| CA2710518C (en) * | 2007-12-27 | 2018-07-17 | Baxter International Inc. | Method and compositions for specifically detecting physiologically acceptable polymer molecules |
| WO2009086262A1 (en) * | 2007-12-27 | 2009-07-09 | Baxter International Inc. | Methods for differentiating plasma-derived protein from recombinant protein in a sample |
| WO2009121551A1 (en) * | 2008-04-03 | 2009-10-08 | F. Hoffmann-La Roche Ag | Pegylated insulin-like-growth-factor assay |
| EP2431741B1 (en) * | 2008-10-21 | 2013-08-21 | Baxter International Inc | Methods for determining active ingredients in pro-drug PEG protein conjugates with releasable PEG reagents (in vitro de-pegylation) |
| DK2459224T3 (en) | 2009-07-27 | 2016-07-25 | Baxalta GmbH | Blodstørkningsproteinkonjugater |
| NZ597600A (en) | 2009-07-27 | 2014-05-30 | Lipoxen Technologies Ltd | Glycopolysialylation of non-blood coagulation proteins |
| US8642737B2 (en) | 2010-07-26 | 2014-02-04 | Baxter International Inc. | Nucleophilic catalysts for oxime linkage |
| GB2488532B (en) * | 2011-02-18 | 2013-06-05 | Sca Ipla Holdings Inc | Communication units and methods for control change notification in broadcast communication |
-
2012
- 2012-05-18 WO PCT/US2012/038704 patent/WO2012159084A1/en active Application Filing
- 2012-05-18 PT PT12725954T patent/PT2710375T/pt unknown
- 2012-05-18 PL PL19161002T patent/PL3517956T3/pl unknown
- 2012-05-18 PT PT191610021T patent/PT3517956T/pt unknown
- 2012-05-18 EP EP19161002.1A patent/EP3517956B1/en active Active
- 2012-05-18 DK DK12725954.7T patent/DK2710375T3/en active
- 2012-05-18 EP EP21190282.0A patent/EP3943939A1/en active Pending
- 2012-05-18 JP JP2014511600A patent/JP6175426B2/ja active Active
- 2012-05-18 DK DK19161002.1T patent/DK3517956T3/da active
- 2012-05-18 EP EP12725954.7A patent/EP2710375B1/en active Active
- 2012-05-18 ES ES12725954T patent/ES2720138T3/es active Active
- 2012-05-18 PL PL12725954T patent/PL2710375T3/pl unknown
- 2012-05-18 AU AU2012255066A patent/AU2012255066B2/en active Active
- 2012-05-18 ES ES19161002T patent/ES2893605T3/es active Active
- 2012-05-18 CA CA2836103A patent/CA2836103C/en active Active
- 2012-05-18 US US13/475,634 patent/US8785139B2/en active Active
- 2012-05-18 TR TR2019/04997T patent/TR201904997T4/tr unknown
-
2016
- 2016-05-24 AU AU2016203387A patent/AU2016203387B2/en active Active
-
2017
- 2017-04-13 JP JP2017079848A patent/JP2017161536A/ja active Pending
-
2018
- 2018-11-08 JP JP2018210141A patent/JP6863950B2/ja active Active
-
2020
- 2020-12-16 JP JP2020208021A patent/JP7242627B2/ja active Active
-
2023
- 2023-03-08 JP JP2023035124A patent/JP2023081972A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012159084A1 (en) | 2012-11-22 |
| JP2014524010A (ja) | 2014-09-18 |
| ES2893605T3 (es) | 2022-02-09 |
| ES2720138T3 (es) | 2019-07-18 |
| US20120329072A1 (en) | 2012-12-27 |
| JP2021063816A (ja) | 2021-04-22 |
| EP2710375B1 (en) | 2019-03-13 |
| JP7242627B2 (ja) | 2023-03-20 |
| DK2710375T3 (en) | 2019-04-29 |
| PL2710375T3 (pl) | 2019-07-31 |
| AU2016203387B2 (en) | 2018-01-25 |
| DK3517956T3 (da) | 2021-10-11 |
| PL3517956T3 (pl) | 2021-12-20 |
| CA2836103C (en) | 2020-07-14 |
| AU2012255066A1 (en) | 2013-05-02 |
| JP2019035765A (ja) | 2019-03-07 |
| JP6175426B2 (ja) | 2017-08-02 |
| JP2017161536A (ja) | 2017-09-14 |
| CA2836103A1 (en) | 2012-11-22 |
| EP3943939A1 (en) | 2022-01-26 |
| PT2710375T (pt) | 2019-05-08 |
| EP3517956B1 (en) | 2021-09-08 |
| US8785139B2 (en) | 2014-07-22 |
| EP2710375A1 (en) | 2014-03-26 |
| AU2016203387A1 (en) | 2016-06-16 |
| EP3517956A1 (en) | 2019-07-31 |
| JP6863950B2 (ja) | 2021-04-21 |
| JP2023081972A (ja) | 2023-06-13 |
| AU2012255066B2 (en) | 2016-06-02 |
| TR201904997T4 (tr) | 2019-05-21 |
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