AU2012254150B2 - Assays for detecting autoantibodies to anti-TNFalpha drugs - Google Patents

Assays for detecting autoantibodies to anti-TNFalpha drugs Download PDF

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Publication number
AU2012254150B2
AU2012254150B2 AU2012254150A AU2012254150A AU2012254150B2 AU 2012254150 B2 AU2012254150 B2 AU 2012254150B2 AU 2012254150 A AU2012254150 A AU 2012254150A AU 2012254150 A AU2012254150 A AU 2012254150A AU 2012254150 B2 AU2012254150 B2 AU 2012254150B2
Authority
AU
Australia
Prior art keywords
tnfa
labeled
sample
drug
tnfa drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2012254150A
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English (en)
Other versions
AU2012254150A1 (en
Inventor
Scott Hauenstein
Linda Ohrmund
Sharat Singh
Shui Long Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Original Assignee
Societe des Produits Nestle SA
Nestle SA
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Publication of AU2012254150A1 publication Critical patent/AU2012254150A1/en
Application granted granted Critical
Publication of AU2012254150B2 publication Critical patent/AU2012254150B2/en
Assigned to Société des Produits Nestlé S.A. reassignment Société des Produits Nestlé S.A. Request for Assignment Assignors: NESTEC S.A.
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2012254150A 2011-02-17 2012-02-16 Assays for detecting autoantibodies to anti-TNFalpha drugs Ceased AU2012254150B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161444097P 2011-02-17 2011-02-17
US61/444,097 2011-02-17
US201161484594P 2011-05-10 2011-05-10
US61/484,594 2011-05-10
US201161496501P 2011-06-13 2011-06-13
US61/496,501 2011-06-13
PCT/US2012/025437 WO2012154253A1 (en) 2011-02-17 2012-02-16 ASSAYS FOR DETECTING AUTOANTIBODIES TO ANTI-TNFα DRUGS

Publications (2)

Publication Number Publication Date
AU2012254150A1 AU2012254150A1 (en) 2013-05-02
AU2012254150B2 true AU2012254150B2 (en) 2015-08-13

Family

ID=45809635

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012254150A Ceased AU2012254150B2 (en) 2011-02-17 2012-02-16 Assays for detecting autoantibodies to anti-TNFalpha drugs

Country Status (16)

Country Link
US (1) US20140045276A1 (enExample)
EP (1) EP2676137B1 (enExample)
JP (1) JP6063398B2 (enExample)
KR (1) KR20140008397A (enExample)
CN (1) CN103502815B (enExample)
AU (1) AU2012254150B2 (enExample)
BR (1) BR112013020981A2 (enExample)
CA (1) CA2827609A1 (enExample)
DK (1) DK2676137T3 (enExample)
ES (1) ES2530175T3 (enExample)
IL (1) IL227853A (enExample)
MX (1) MX343327B (enExample)
RU (1) RU2013142278A (enExample)
SG (1) SG192770A1 (enExample)
WO (1) WO2012154253A1 (enExample)
ZA (1) ZA201306950B (enExample)

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CN112362649B (zh) * 2020-11-09 2024-07-12 长春金赛药业有限责任公司 一种rhGH中和抗体的检测方法
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12281359B2 (en) 2013-05-17 2025-04-22 Cedars-Sinai Medical Center Variants of TNFSF15 and DCR3 associated with Crohn's disease

Also Published As

Publication number Publication date
MX2013009570A (es) 2013-09-06
SG192770A1 (en) 2013-09-30
IL227853A0 (en) 2013-09-30
JP6063398B2 (ja) 2017-01-18
EP2676137B1 (en) 2014-12-31
CN103502815B (zh) 2015-09-23
AU2012254150A1 (en) 2013-05-02
JP2014508930A (ja) 2014-04-10
BR112013020981A2 (pt) 2016-10-11
KR20140008397A (ko) 2014-01-21
CN103502815A (zh) 2014-01-08
MX343327B (es) 2016-11-01
ES2530175T3 (es) 2015-02-26
RU2013142278A (ru) 2015-03-27
EP2676137A1 (en) 2013-12-25
US20140045276A1 (en) 2014-02-13
ZA201306950B (en) 2015-04-29
NZ614170A (en) 2015-04-24
HK1191688A1 (en) 2014-08-01
WO2012154253A1 (en) 2012-11-15
IL227853A (en) 2017-07-31
CA2827609A1 (en) 2012-11-15
DK2676137T3 (en) 2015-01-19

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Owner name: SOCIETE DES PRODUITS NESTLE S.A.

Free format text: FORMER OWNER(S): NESTEC S.A.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired