AU2011329854B2 - CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells - Google Patents
CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells Download PDFInfo
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- AU2011329854B2 AU2011329854B2 AU2011329854A AU2011329854A AU2011329854B2 AU 2011329854 B2 AU2011329854 B2 AU 2011329854B2 AU 2011329854 A AU2011329854 A AU 2011329854A AU 2011329854 A AU2011329854 A AU 2011329854A AU 2011329854 B2 AU2011329854 B2 AU 2011329854B2
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- Prior art keywords
- catenin
- optionally substituted
- cbp
- cells
- alkyl
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2017201750A AU2017201750B9 (en) | 2010-11-16 | 2017-03-15 | CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41433410P | 2010-11-16 | 2010-11-16 | |
| US41434810P | 2010-11-16 | 2010-11-16 | |
| US61/414,348 | 2010-11-16 | ||
| US61/414,334 | 2010-11-16 | ||
| US201161545033P | 2011-10-07 | 2011-10-07 | |
| US61/545,033 | 2011-10-07 | ||
| PCT/US2011/061062 WO2012068299A2 (en) | 2010-11-16 | 2011-11-16 | Cbp/catenin antagonists for enhancing asymmetric division of somatic stem cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2017201750A Division AU2017201750B9 (en) | 2010-11-16 | 2017-03-15 | CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2011329854A1 AU2011329854A1 (en) | 2013-07-04 |
| AU2011329854B2 true AU2011329854B2 (en) | 2017-03-30 |
Family
ID=46084627
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2011329854A Active AU2011329854B2 (en) | 2010-11-16 | 2011-11-16 | CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells |
| AU2017201750A Active AU2017201750B9 (en) | 2010-11-16 | 2017-03-15 | CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2017201750A Active AU2017201750B9 (en) | 2010-11-16 | 2017-03-15 | CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10092568B2 (enExample) |
| EP (1) | EP2640393B1 (enExample) |
| JP (2) | JP6163105B2 (enExample) |
| KR (1) | KR102077871B1 (enExample) |
| CN (1) | CN103476415B (enExample) |
| AU (2) | AU2011329854B2 (enExample) |
| BR (1) | BR112013012228B1 (enExample) |
| CA (1) | CA2817975C (enExample) |
| ES (1) | ES2935544T3 (enExample) |
| WO (1) | WO2012068299A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| BR112013012228B1 (pt) * | 2010-11-16 | 2023-02-28 | University Of Southern California | Método cosmético para tratar uma condição da pele e usos de um composto antagonista de cbp/catenina de molécula pequena |
| AU2012319069A1 (en) | 2011-10-07 | 2014-05-29 | University Of Southern California | CBP/catenin antagonists for enhancing asymmetric division of somatic stem cells |
| WO2014025832A1 (en) * | 2012-08-06 | 2014-02-13 | University Of Southern California | Wnt modulators for the protection, mitigation and treatment of radiation injury |
| WO2014061825A1 (en) * | 2012-10-19 | 2014-04-24 | Hiroyuki Kouji | Treatment of viral and infectious diseases using an inhibitor of cbp/catenin |
| JP2016502497A (ja) * | 2012-10-19 | 2016-01-28 | 株式会社PRISM Pharma | I型およびii型糖尿病を治療する方法 |
| EP2908822A4 (en) * | 2012-10-19 | 2016-04-27 | Prism Pharma Co Ltd | TREATMENT OF HYPERPROLIFERATIVE AND PRECANCEROUS DISEASES OF THE SKIN USING A CBP / CATENIN INHIBITOR |
| EP2908820A1 (en) * | 2012-10-19 | 2015-08-26 | Prism Pharma Co., Ltd. | Treatment of pulmonary fibrosis using an inhibitor of cbp/catenin |
| AU2013332731A1 (en) * | 2012-10-19 | 2015-06-04 | Prism Pharma Co., Ltd. | Methods for treating eye disorders |
| JP2015536300A (ja) * | 2012-10-19 | 2015-12-21 | 株式会社PRISM Pharma | Cbp/カテニン阻害剤を用いる強皮症の治療 |
| US11229789B2 (en) | 2013-05-30 | 2022-01-25 | Neurostim Oab, Inc. | Neuro activator with controller |
| PL3003473T3 (pl) | 2013-05-30 | 2019-05-31 | Neurostim Solutions LLC | Miejscowa stymulacja neurologiczna |
| CN104231048B (zh) * | 2013-06-05 | 2017-05-24 | 财团法人工业技术研究院 | 生发胜肽及药物组合物 |
| WO2015157771A1 (en) * | 2014-04-11 | 2015-10-15 | Bcs Business Consulting Services Pte Ltd | Hair enhancing formulation |
| RU2549987C1 (ru) * | 2014-06-17 | 2015-05-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Средство для ускорения заживления ран и регенерации тканей |
| US11077301B2 (en) | 2015-02-21 | 2021-08-03 | NeurostimOAB, Inc. | Topical nerve stimulator and sensor for bladder control |
| US10639350B2 (en) | 2015-08-10 | 2020-05-05 | The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center | Methods and pharmaceutical compositions for improving wound healing using CD24 |
| WO2017044302A1 (en) * | 2015-09-09 | 2017-03-16 | Rush University Medical Center | Compositions and methods for treating bone diseases |
| EP3366687B1 (en) * | 2015-09-18 | 2020-04-29 | National University Corporation Tottori University | Suppression and regeneration promoting effect of low molecular weight compound on cancer and fibrosis |
| EP3320901B1 (en) * | 2016-01-28 | 2020-03-04 | Accendatech | Dimethylaminomicheliolide for use in the treatment of pulmonary fibrosis |
| CN105854018B (zh) * | 2016-03-28 | 2018-11-13 | 杭州师范大学 | Wnt抑制剂在制备治疗造血再生障碍性疾病药物中的应用 |
| US20190125753A1 (en) * | 2016-04-20 | 2019-05-02 | University Of Southern California | Compounds and methods for increasing hematopoiesis |
| WO2019018441A1 (en) * | 2017-07-17 | 2019-01-24 | Massachusetts Institute Of Technology | ATLAS OF HEAVY AND ILLUMINATED HEAVY BARRIER TISSUE CELLS |
| CN111601636A (zh) | 2017-11-07 | 2020-08-28 | Oab神经电疗科技公司 | 具有自适应电路的非侵入性神经激活器 |
| JP7605576B2 (ja) | 2018-07-25 | 2024-12-24 | ポーラ化成工業株式会社 | 皮膚老化改善剤のスクリーニング方法 |
| EP3990100A4 (en) | 2019-06-26 | 2023-07-19 | Neurostim Technologies LLC | Non-invasive nerve activator with adaptive circuit |
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| KR102612610B1 (ko) * | 2020-02-07 | 2023-12-12 | 주식회사 한스파마 | 신경줄기세포의 제조방법 및 이로부터 얻어진 신경줄기세포 배양액을 유효성분으로 포함하는 피부 재생, 항산화, 항염증 및 상처 치료용 조성물 |
| WO2021183791A1 (en) | 2020-03-12 | 2021-09-16 | City Of Hope | Wnt/cbp/catenin signaling pathway inhibitors and uses thereof |
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| JP7178143B1 (ja) | 2022-03-17 | 2022-11-25 | 学校法人関西医科大学 | 爪幹細胞及び毛髪の成長を助長する外用剤 |
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| US10092568B2 (en) | 2018-10-09 |
| AU2017201750A1 (en) | 2017-03-30 |
| CN103476415B (zh) | 2017-09-22 |
| EP2640393A4 (en) | 2015-05-27 |
| WO2012068299A2 (en) | 2012-05-24 |
| AU2011329854A1 (en) | 2013-07-04 |
| CN103476415A (zh) | 2013-12-25 |
| JP6518706B2 (ja) | 2019-05-22 |
| JP2013542999A (ja) | 2013-11-28 |
| WO2012068299A9 (en) | 2013-06-20 |
| EP2640393A2 (en) | 2013-09-25 |
| KR102077871B1 (ko) | 2020-02-14 |
| CA2817975A1 (en) | 2012-05-24 |
| US20130280233A1 (en) | 2013-10-24 |
| KR20130140079A (ko) | 2013-12-23 |
| JP6163105B2 (ja) | 2017-07-12 |
| CA2817975C (en) | 2020-03-31 |
| AU2017201750B9 (en) | 2019-01-31 |
| JP2017088633A (ja) | 2017-05-25 |
| ES2935544T3 (es) | 2023-03-07 |
| BR112013012228A2 (pt) | 2021-05-18 |
| BR112013012228B1 (pt) | 2023-02-28 |
| AU2017201750B2 (en) | 2019-01-17 |
| EP2640393B1 (en) | 2022-10-12 |
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