AU2011213234B2 - Systems and methods for manipulating a molecule in a nanopore - Google Patents

Systems and methods for manipulating a molecule in a nanopore Download PDF

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Publication number
AU2011213234B2
AU2011213234B2 AU2011213234A AU2011213234A AU2011213234B2 AU 2011213234 B2 AU2011213234 B2 AU 2011213234B2 AU 2011213234 A AU2011213234 A AU 2011213234A AU 2011213234 A AU2011213234 A AU 2011213234A AU 2011213234 B2 AU2011213234 B2 AU 2011213234B2
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nanopore
molecule
lipid bilayer
electrical stimulus
electrical
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AU2011213234A2 (en
AU2011213234A1 (en
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Roger Chen
Randy Davis
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Priority claimed from US12/658,602 external-priority patent/US20120052188A1/en
Priority claimed from US12/658,601 external-priority patent/US20110192723A1/en
Priority claimed from US12/658,591 external-priority patent/US9605307B2/en
Priority claimed from US12/658,604 external-priority patent/US8324914B2/en
Priority claimed from US12/658,603 external-priority patent/US20110287414A1/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2011213234A1 publication Critical patent/AU2011213234A1/en
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Priority to AU2015207973A priority Critical patent/AU2015207973B2/en
Assigned to F. HOFFMANN-LA ROCHE AG reassignment F. HOFFMANN-LA ROCHE AG Request for Assignment Assignors: Genia Technologies, Inc.
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AU2011213234A 2010-02-08 2011-02-04 Systems and methods for manipulating a molecule in a nanopore Active AU2011213234B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2015207973A AU2015207973B2 (en) 2010-02-08 2015-08-03 Systems and methods for manipulating a molecule in a nanopore

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US12/658,591 2010-02-08
US12/658,591 US9605307B2 (en) 2010-02-08 2010-02-08 Systems and methods for forming a nanopore in a lipid bilayer
US12/658,603 2010-02-08
US12/658,601 2010-02-08
US12/658,601 US20110192723A1 (en) 2010-02-08 2010-02-08 Systems and methods for manipulating a molecule in a nanopore
US12/658,602 2010-02-08
US12/658,604 2010-02-08
US12/658,603 US20110287414A1 (en) 2010-02-08 2010-02-08 Systems and methods for identifying a portion of a molecule
US12/658,602 US20120052188A1 (en) 2010-02-08 2010-02-08 Systems and methods for assembling a lipid bilayer on a substantially planar solid surface
US12/658,604 US8324914B2 (en) 2010-02-08 2010-02-08 Systems and methods for characterizing a molecule
PCT/US2011/000205 WO2011097028A1 (en) 2010-02-08 2011-02-04 Systems and methods for manipulating a molecule in a nanopore

Related Child Applications (1)

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AU2015207973A Division AU2015207973B2 (en) 2010-02-08 2015-08-03 Systems and methods for manipulating a molecule in a nanopore

Publications (3)

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AU2011213234A1 AU2011213234A1 (en) 2012-08-23
AU2011213234A2 AU2011213234A2 (en) 2013-01-10
AU2011213234B2 true AU2011213234B2 (en) 2015-05-14

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EP (2) EP2843405B8 (enExample)
JP (2) JP5858931B2 (enExample)
CN (2) CN105273991B (enExample)
AU (1) AU2011213234B2 (enExample)
CA (2) CA2995178C (enExample)
GB (2) GB2496019B (enExample)
WO (1) WO2011097028A1 (enExample)

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Also Published As

Publication number Publication date
CN105273991A (zh) 2016-01-27
CN103298984A (zh) 2013-09-11
CA2995178C (en) 2023-09-12
EP2843405B8 (en) 2023-10-04
JP6124982B2 (ja) 2017-05-10
GB201216656D0 (en) 2012-10-31
JP2016095314A (ja) 2016-05-26
JP2013519088A (ja) 2013-05-23
GB2496019B (en) 2014-11-12
GB2490847A8 (en) 2014-10-22
JP5858931B2 (ja) 2016-02-10
CN105273991B (zh) 2019-05-10
GB2490847A (en) 2012-11-14
AU2011213234A2 (en) 2013-01-10
CN103298984B (zh) 2015-11-25
EP2843405A2 (en) 2015-03-04
EP2534284A1 (en) 2012-12-19
GB2490847B (en) 2014-04-23
EP2843405A3 (en) 2015-04-29
AU2011213234A1 (en) 2012-08-23
GB201216026D0 (en) 2012-10-24
EP2843405B1 (en) 2023-08-23
EP2534284B1 (en) 2021-03-17
EP2534284A4 (en) 2017-01-25
GB2496019A (en) 2013-05-01
GB2490847B8 (en) 2014-10-22
WO2011097028A1 (en) 2011-08-11
CA2788331C (en) 2018-04-03
CA2995178A1 (en) 2011-08-11
CA2788331A1 (en) 2011-08-11

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