AU2010275699B2 - Markers for endometrial cancer - Google Patents

Markers for endometrial cancer Download PDF

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Publication number
AU2010275699B2
AU2010275699B2 AU2010275699A AU2010275699A AU2010275699B2 AU 2010275699 B2 AU2010275699 B2 AU 2010275699B2 AU 2010275699 A AU2010275699 A AU 2010275699A AU 2010275699 A AU2010275699 A AU 2010275699A AU 2010275699 B2 AU2010275699 B2 AU 2010275699B2
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endometrial cancer
p4hb
biomarkers
ikbke
gmip
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AU2010275699A1 (en
Inventor
Miguel Abal Posada
Andreas Doll
Antonio Gil Moreno
Tamara Maes
Cristina Perez
Jaume Reventos Puigjaner
Elisabet Rossell
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Geadic Biotec AIE
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Geadic Biotec AIE
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57442Specifically defined cancers of the uterus and endometrial
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069Reproductive system, e.g. ovaria, uterus, testes, prostate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2010275699A 2009-07-24 2010-07-23 Markers for endometrial cancer Active AU2010275699B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09166398 2009-07-24
EP09166398.9 2009-07-24
PCT/EP2010/004550 WO2011009637A2 (en) 2009-07-24 2010-07-23 Markers for endometrial cancer

Publications (2)

Publication Number Publication Date
AU2010275699A1 AU2010275699A1 (en) 2012-02-02
AU2010275699B2 true AU2010275699B2 (en) 2016-06-16

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AU2010275699A Active AU2010275699B2 (en) 2009-07-24 2010-07-23 Markers for endometrial cancer

Country Status (17)

Country Link
US (2) US9046522B2 (da)
EP (2) EP2456889B1 (da)
JP (1) JP5934093B2 (da)
KR (1) KR101828290B1 (da)
CN (2) CN102549169B (da)
AU (1) AU2010275699B2 (da)
BR (1) BR112012001469B1 (da)
CA (1) CA2767914C (da)
DK (1) DK2456889T3 (da)
ES (2) ES2654340T3 (da)
HR (1) HRP20141062T1 (da)
IN (1) IN2012DN00707A (da)
MX (1) MX2012000921A (da)
PL (1) PL2456889T3 (da)
PT (1) PT2456889E (da)
RU (1) RU2596394C2 (da)
WO (1) WO2011009637A2 (da)

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CN102549169B (zh) * 2009-07-24 2016-02-24 吉第克生物技术有限公司 子宫内膜癌的标记物
CN107389936A (zh) * 2011-09-22 2017-11-24 斯隆-凯特林纪念癌症中心 检测卵巢癌
EP2787350A1 (en) * 2013-04-05 2014-10-08 Atlas Antibodies AB ASRGL1 in endometrial cancer
KR102113310B1 (ko) * 2013-09-03 2020-05-20 아주대학교 산학협력단 암 세포 분리용 조성물, 키트 및 이를 이용한 분리 방법
CN114190990A (zh) 2014-08-12 2022-03-18 新生代吉恩公司 用于基于收集的体液而监测健康的系统和方法
NZ730664A (en) * 2014-09-17 2023-12-22 Merck Patent Gmbh A method of treating bone metastasis diseases, medicaments therefore, and a method of predicting the clinical outcome of treating bone metastasis diseases
CN107102141A (zh) * 2016-02-23 2017-08-29 中国科学院生物物理研究所 分子标记物cd71及在子宫内膜癌诊断、分期及预后中的应用
WO2017180909A1 (en) 2016-04-13 2017-10-19 Nextgen Jane, Inc. Sample collection and preservation devices, systems and methods
AU2017260806B9 (en) * 2016-05-04 2023-07-20 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Markers of endometrial cancer
GB201702392D0 (en) * 2017-02-14 2017-03-29 Univ Edinburgh Methods for cancer diagnosis using a gene expression signature
CN108732349A (zh) * 2017-04-20 2018-11-02 中国科学院上海生命科学研究院 Lta4h作为指示肝内结节及早期预警肝癌的生物标志物
CN108732350A (zh) * 2017-04-20 2018-11-02 中国科学院上海生命科学研究院 Pla2g6作为指示肝内结节及早期预警肝癌的生物标志物
CN108732351A (zh) * 2017-04-20 2018-11-02 中国科学院上海生命科学研究院 Eps8l2作为指示肝内结节及早期预警肝癌的生物标志物
CN109085359A (zh) * 2017-06-13 2018-12-25 中国医学科学院肿瘤医院 血清蛋白标志物组合在结直肠癌筛查和诊治中的应用
WO2019016400A1 (en) * 2017-07-21 2019-01-24 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca CTNB1 AS A MARKER FOR CANCER OF THE ENDOMETER
CN109097462B (zh) * 2018-09-10 2022-01-11 青岛市海慈医疗集团 Ap1m2基因作为诊断青光眼的分子标志物的应用
WO2020130190A1 (ko) * 2018-12-20 2020-06-25 경상대학교병원 신장암의 발병 위험성 예측 또는 진단을 위한 정보제공방법
CN109797217A (zh) * 2019-03-27 2019-05-24 河北医科大学第二医院 帕金森生物标志物及其在制备检测产品中的应用
CN109811058B (zh) * 2019-03-31 2021-11-12 青岛泱深生物医药有限公司 与宫颈疾病发生发展相关的生物标志物及其应用
WO2022226381A1 (en) * 2021-04-22 2022-10-27 H. Lee Moffitt Cancer Center And Research Institute, Inc. Diagnostic to support clinical trial matching and exploratory biomarker analyses in cancer patients
KR102584898B1 (ko) * 2022-10-24 2023-10-04 연세대학교 산학협력단 자궁내막암 진단 방법 및 이를 이용한 키트

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Also Published As

Publication number Publication date
IN2012DN00707A (da) 2015-06-19
DK2456889T3 (da) 2014-12-01
WO2011009637A2 (en) 2011-01-27
EP2456889B1 (en) 2014-09-03
CN102549169A (zh) 2012-07-04
US20120122726A1 (en) 2012-05-17
CA2767914A1 (en) 2011-01-27
ES2523683T3 (es) 2014-11-28
PT2456889E (pt) 2014-11-21
KR101828290B1 (ko) 2018-02-12
EP2848700B1 (en) 2017-10-04
KR20120047334A (ko) 2012-05-11
JP5934093B2 (ja) 2016-06-15
EP2848700A1 (en) 2015-03-18
CN105132529A (zh) 2015-12-09
EP2456889A2 (en) 2012-05-30
CA2767914C (en) 2020-02-25
RU2596394C2 (ru) 2016-09-10
WO2011009637A3 (en) 2011-04-14
PL2456889T3 (pl) 2015-02-27
BR112012001469A2 (pt) 2020-08-11
BR112012001469B1 (pt) 2021-08-10
AU2010275699A1 (en) 2012-02-02
ES2654340T3 (es) 2018-02-13
US20150337392A1 (en) 2015-11-26
US9046522B2 (en) 2015-06-02
CN102549169B (zh) 2016-02-24
RU2012106432A (ru) 2013-08-27
MX2012000921A (es) 2012-06-12
JP2013500001A (ja) 2013-01-07
HRP20141062T1 (hr) 2015-01-02

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