AU2010224125B2 - Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies - Google Patents
Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies Download PDFInfo
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- AU2010224125B2 AU2010224125B2 AU2010224125A AU2010224125A AU2010224125B2 AU 2010224125 B2 AU2010224125 B2 AU 2010224125B2 AU 2010224125 A AU2010224125 A AU 2010224125A AU 2010224125 A AU2010224125 A AU 2010224125A AU 2010224125 B2 AU2010224125 B2 AU 2010224125B2
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| EA024252B1 (ru) | 2009-01-08 | 2016-08-31 | Кьюрис, Инк. | Ингибиторы фосфоинозитид-3-киназ с цинксвязывающей группой |
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| CA2787714C (en) | 2010-01-22 | 2019-04-09 | Joaquin Pastor Fernandez | Inhibitors of pi3 kinase |
| WO2011121317A1 (en) | 2010-04-01 | 2011-10-06 | Centro Nacional De Investigaciones Oncologicas (Cnio) | Imidazo [2,1-b] [1,3,4] thiadiazoles as protein or lipid kinase inhibitors |
| WO2012052745A1 (en) | 2010-10-21 | 2012-04-26 | Centro Nacional De Investigaciones Oncológicas (Cnio) | Combinations of pi3k inhibitors with a second anti -tumor agent |
| WO2012098387A1 (en) | 2011-01-18 | 2012-07-26 | Centro Nacional De Investigaciones Oncológicas (Cnio) | 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors |
| US20140213630A1 (en) * | 2011-03-08 | 2014-07-31 | Thomas Diacovo | Methods and pharmaceutical compositions for treating lymphoid malignancy |
| HUE028910T2 (en) | 2011-04-01 | 2017-01-30 | Curis Inc | Phosphoinositide 3-kinase inhibitor with a zinc binding moiety |
| CN103635183A (zh) * | 2011-04-29 | 2014-03-12 | 埃克塞利希斯股份有限公司 | 使用pi3k/mtor的吡啶并嘧啶抑制剂来治疗淋巴瘤的方法 |
| PT2710018T (pt) | 2011-05-19 | 2022-03-01 | Fundacion Del Sector Publico Estatal Centro Nac De Investigaciones Oncologicas Carlos Iii F S P Cnio | Compostos macrocíclicos como inibidores de proteína quinases |
| EP2524918A1 (en) | 2011-05-19 | 2012-11-21 | Centro Nacional de Investigaciones Oncológicas (CNIO) | Imidazopyrazines derivates as kinase inhibitors |
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| WO2013055996A1 (en) | 2011-10-13 | 2013-04-18 | Genentech, Inc. | Treatment of pharmacological-induced hypochlorhydria |
| MX357100B (es) * | 2011-11-09 | 2018-06-26 | Bristol Myers Squibb Co | Tratamiento de neoplasias hematologicas con un anticuerpo anti-cxcr4. |
| EP2827903A4 (en) * | 2012-03-23 | 2016-02-10 | Sloan Kettering Inst Cancer | POTENTIATION OF ANTIBODY-INDUCED COMPLEMENT-MEDIATED CYTOTOXICITY BY PI3K INHIBITION |
| CN103467482B (zh) * | 2012-04-10 | 2017-05-10 | 上海璎黎药业有限公司 | 稠合嘧啶类化合物，其制备方法，中间体，组合物和应用 |
| RU2014149145A (ru) | 2012-05-23 | 2016-07-20 | Ф. Хоффманн-Ля Рош Аг | Композиции и способы получения и применения эндодермальных клеток и гепатоцитов |
| SG10201706196XA (en) | 2012-06-08 | 2017-08-30 | Hoffmann La Roche | Mutant selectivity and combinations of a phosphoinositide 3 kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer |
| CA2883513A1 (en) * | 2012-10-10 | 2014-04-17 | F. Hoffmann-La Roche Ag | Process for making thienopyrimidine compounds |
| EP3756686A1 (en) * | 2012-11-02 | 2020-12-30 | TG Therapeutics Inc. | Combination of anti-cd20 antibody and pi3 kinase selective inhibitor |
| US20160022757A1 (en) * | 2013-03-15 | 2016-01-28 | Icahn School Of Medicine At Mount Sinai | Therapeutic methods for treating solid tumors and related diagnostic methods |
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| JP6871919B2 (ja) | 2015-06-16 | 2021-05-19 | ナノファギックス エルエルシー | 薬物送達及びイメージング化学コンジュゲート、製剤及びその使用方法 |
| AU2016287189A1 (en) | 2015-06-29 | 2017-10-12 | F. Hoffmann-La Roche Ag | Methods of treatment with taselisib |
| TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| EP3476949A1 (en) * | 2017-10-31 | 2019-05-01 | Centre National De La Recherche Scientifique | Prognosis method of multiple myeloma |
| WO2020055840A1 (en) | 2018-09-11 | 2020-03-19 | Curis Inc. | Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety |
| WO2020087077A1 (en) * | 2018-10-26 | 2020-04-30 | Syndevrx,Inc. | Biomarkers of metap2 inhibitors and applications thereof |
| WO2020146613A1 (en) * | 2019-01-10 | 2020-07-16 | Mirati Therapeutics, Inc. | Kras g12c inhibitors |
| WO2021050672A1 (en) * | 2019-09-11 | 2021-03-18 | Ohio State Innovation Foundation | Kinase inhibitors for the treatment of neurodegenerative diseases |
| EP4631948A1 (en) * | 2022-12-07 | 2025-10-15 | SK Biopharmaceuticals Co., Ltd. | Novel tricyclic compound as kras g12d inhibitor, and use thereof |
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- 2010-03-11 BR BRPI1006189-4A patent/BRPI1006189A2/pt not_active IP Right Cessation
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007127175A2 (en) * | 2006-04-26 | 2007-11-08 | F. Hoffmann-La Roche Ag | Pharmaceutical compounds |
| WO2007129161A2 (en) * | 2006-04-26 | 2007-11-15 | F. Hoffmann-La Roche Ag | Thieno [3, 2-d] pyrimidine derivative useful as pi3k inhibitor |
| WO2009030682A1 (fr) * | 2007-09-05 | 2009-03-12 | European Aeronautic Defence And Space Company - Eads France | Methode et dispositif d'analyse des procedes de fabrication de pieces en materiaux composites, par infusion ou injection, et de caracterisation de ces materiaux composites |
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| AU2010224125A1 (en) | 2011-08-04 |
| WO2010105008A2 (en) | 2010-09-16 |
| IL214132A (en) | 2015-02-26 |
| US9335320B2 (en) | 2016-05-10 |
| KR101781654B1 (ko) | 2017-09-25 |
| MX2011009167A (es) | 2011-09-15 |
| CA2753285A1 (en) | 2010-09-16 |
| US8536161B2 (en) | 2013-09-17 |
| BRPI1006189A2 (pt) | 2020-08-18 |
| IL214132A0 (en) | 2011-08-31 |
| WO2010105008A3 (en) | 2010-11-25 |
| JP5709766B2 (ja) | 2015-04-30 |
| JP2012520313A (ja) | 2012-09-06 |
| KR20110132442A (ko) | 2011-12-07 |
| US20130330765A1 (en) | 2013-12-12 |
| EP2405916A2 (en) | 2012-01-18 |
| EP2405916B1 (en) | 2018-02-07 |
| US20100233164A1 (en) | 2010-09-16 |
| CN102369011A (zh) | 2012-03-07 |
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