AU2009330727B2 - Combination of Aurora kinase inhibitors and anti-CD20 antibodies - Google Patents

Combination of Aurora kinase inhibitors and anti-CD20 antibodies Download PDF

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Publication number
AU2009330727B2
AU2009330727B2 AU2009330727A AU2009330727A AU2009330727B2 AU 2009330727 B2 AU2009330727 B2 AU 2009330727B2 AU 2009330727 A AU2009330727 A AU 2009330727A AU 2009330727 A AU2009330727 A AU 2009330727A AU 2009330727 B2 AU2009330727 B2 AU 2009330727B2
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AU
Australia
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group
ring
optionally substituted
aliphatic
heteroaryl
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Ceased
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AU2009330727A
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AU2009330727A1 (en
Inventor
Mark Manfredi
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Millennium Pharmaceuticals Inc
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Millennium Pharmaceuticals Inc
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Publication of AU2009330727B2 publication Critical patent/AU2009330727B2/en
Ceased legal-status Critical Current
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2009330727A 2008-12-22 2009-12-15 Combination of Aurora kinase inhibitors and anti-CD20 antibodies Ceased AU2009330727B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20350908P 2008-12-22 2008-12-22
US61/203,509 2008-12-22
PCT/US2009/006560 WO2010074724A1 (en) 2008-12-22 2009-12-15 Combination of aurora kinase inhibitors and anti-cd20 antibodies

Publications (2)

Publication Number Publication Date
AU2009330727A1 AU2009330727A1 (en) 2011-07-07
AU2009330727B2 true AU2009330727B2 (en) 2016-07-28

Family

ID=41664630

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009330727A Ceased AU2009330727B2 (en) 2008-12-22 2009-12-15 Combination of Aurora kinase inhibitors and anti-CD20 antibodies

Country Status (13)

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US (3) US20100183601A1 (US07794700-20100914-C00152.png)
EP (1) EP2376082B1 (US07794700-20100914-C00152.png)
JP (1) JP5738196B2 (US07794700-20100914-C00152.png)
KR (1) KR101741168B1 (US07794700-20100914-C00152.png)
CN (1) CN102264368B (US07794700-20100914-C00152.png)
AU (1) AU2009330727B2 (US07794700-20100914-C00152.png)
BR (1) BRPI0923579A2 (US07794700-20100914-C00152.png)
CA (1) CA2747326C (US07794700-20100914-C00152.png)
ES (1) ES2468391T3 (US07794700-20100914-C00152.png)
HK (1) HK1160766A1 (US07794700-20100914-C00152.png)
MX (1) MX2011006725A (US07794700-20100914-C00152.png)
RU (1) RU2535032C2 (US07794700-20100914-C00152.png)
WO (1) WO2010074724A1 (US07794700-20100914-C00152.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009330727B2 (en) 2008-12-22 2016-07-28 Millennium Pharmaceuticals, Inc. Combination of Aurora kinase inhibitors and anti-CD20 antibodies
JO3434B1 (ar) 2009-07-31 2019-10-20 Millennium Pharm Inc مركبات صيدلانية لمعالجة السرطان وامراض واضطرابات اخري
US8653064B2 (en) 2010-02-19 2014-02-18 Millennium Pharmaceuticals, Inc. Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-D][2]benzazepin-2-yl]amino}-2-methoxybenzoate
WO2014153509A1 (en) * 2013-03-22 2014-09-25 Millennium Pharmaceuticals, Inc. Combination of catalytic mtorc 1/2 inhibitors and selective inhibitors of aurora a kinase
WO2015085289A1 (en) 2013-12-06 2015-06-11 Millennium Pharmaceuticals, Inc. Combination of aurora kinase inhibitors and anti-cd30 antibodies
US20180206726A1 (en) 2016-12-07 2018-07-26 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
US20210138213A1 (en) 2017-03-30 2021-05-13 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
WO2019246317A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease or condition in a tissue originating from the endoderm
US20230041197A1 (en) 2018-06-20 2023-02-09 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
WO2020106704A2 (en) 2018-11-19 2020-05-28 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
WO2021119482A1 (en) 2019-12-13 2021-06-17 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract

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Also Published As

Publication number Publication date
BRPI0923579A2 (pt) 2020-01-14
RU2535032C2 (ru) 2014-12-10
EP2376082A1 (en) 2011-10-19
KR20110114586A (ko) 2011-10-19
CN102264368A (zh) 2011-11-30
AU2009330727A1 (en) 2011-07-07
CA2747326A1 (en) 2010-07-01
US10391100B2 (en) 2019-08-27
HK1160766A1 (en) 2012-08-17
KR101741168B1 (ko) 2017-05-29
CN102264368B (zh) 2014-09-10
JP2012513390A (ja) 2012-06-14
US20160271249A1 (en) 2016-09-22
JP5738196B2 (ja) 2015-06-17
ES2468391T3 (es) 2014-06-16
EP2376082B1 (en) 2014-03-05
US20170296551A1 (en) 2017-10-19
CA2747326C (en) 2017-05-16
US20100183601A1 (en) 2010-07-22
WO2010074724A1 (en) 2010-07-01
RU2011130566A (ru) 2013-01-27
MX2011006725A (es) 2011-09-15

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