AU2009322045A1 - Peptide therapeutic conjugates and uses thereof - Google Patents
Peptide therapeutic conjugates and uses thereof Download PDFInfo
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- AU2009322045A1 AU2009322045A1 AU2009322045A AU2009322045A AU2009322045A1 AU 2009322045 A1 AU2009322045 A1 AU 2009322045A1 AU 2009322045 A AU2009322045 A AU 2009322045A AU 2009322045 A AU2009322045 A AU 2009322045A AU 2009322045 A1 AU2009322045 A1 AU 2009322045A1
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8114—Kunitz type inhibitors
- C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
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| US61/200,947 | 2008-12-05 | ||
| PCT/CA2009/001781 WO2010063124A1 (en) | 2008-12-05 | 2009-12-07 | Peptide therapeutic conjugates and uses thereof |
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| AU2009322045A1 true AU2009322045A1 (en) | 2011-07-07 |
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| ZA (1) | ZA201104497B (https=) |
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| ES2744225T3 (es) | 2005-07-15 | 2020-02-24 | Angiochem Inc | Uso de polipéptidos de aprotinina como portadores en conjugados farmacéuticos |
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| US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
| CA2740316A1 (en) * | 2008-10-15 | 2010-04-22 | Angiochem Inc. | Conjugates of glp-1 agonists and uses thereof |
| CA2745524C (en) | 2008-12-05 | 2020-06-09 | Angiochem Inc. | Conjugates of neurotensin or neurotensin analogs and uses thereof |
| US8853353B2 (en) | 2008-12-17 | 2014-10-07 | Angiochem, Inc. | Membrane type-1 matrix metalloprotein inhibitors and uses thereof |
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| RU2012103240A (ru) * | 2009-07-02 | 2013-08-10 | Ангиокем Инк. | Мультимерные пептидные конъюгаты и их применение |
| WO2011070573A1 (en) * | 2009-12-07 | 2011-06-16 | Ben-Gurion University Of The Negev Research And Development Authority | Antimicrobial water treatment membranes and production thereof |
| AU2010327949A1 (en) * | 2009-12-11 | 2012-06-28 | Case Western Reserve University | Insulin analogues with chlorinated amino acids |
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| CU24076B1 (es) * | 2011-09-30 | 2015-01-29 | Ct De Ingeniería Genética Y Biotecnología | Composición para el control de patógenos |
| CN104145015A (zh) * | 2011-12-01 | 2014-11-12 | 安吉奥开米公司 | 靶向的溶酶体酶化合物 |
| BR112014013250A2 (pt) * | 2011-12-01 | 2019-09-24 | Angiochem Inc | compostos com enzima alvo e usos dos mesmos |
| US20150025002A1 (en) * | 2012-01-12 | 2015-01-22 | University Of Ulster | Peptides and peptide derivatives based on xenin |
| WO2013173337A2 (en) * | 2012-05-15 | 2013-11-21 | Seattle Genetics, Inc. | Self-stabilizing linker conjugates |
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| US20170253643A1 (en) * | 2014-09-02 | 2017-09-07 | Tokyo University Of Science Foundation | Centrally-Acting Peptide Derivative, and Pharmaceutical Composition |
| ES2748117T3 (es) * | 2015-04-22 | 2020-03-13 | Euroimmun Medizinische Labordiagnostika Ag | Diagnóstico de una nueva enfermedad autoinmune |
| IL293655B2 (en) * | 2015-05-27 | 2025-04-01 | Univ Northwestern | Modified carbohydrate particles and particulate compositions for modulating immune response |
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| US10858410B2 (en) * | 2015-08-12 | 2020-12-08 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Glycosylated peptides with pseudoproline residues and having enhanced half-lives and ability to cross the blood brain barrier |
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| US10973812B2 (en) | 2016-03-03 | 2021-04-13 | Regents Of The University Of Minnesota | Ataxia therapeutic compositions and methods |
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| WO2019043382A1 (en) * | 2017-08-31 | 2019-03-07 | University Of Dundee | DERIVED LEPTIN PEPTIDES AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL DISORDERS |
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| CN112851789B (zh) * | 2021-02-04 | 2022-10-18 | 大理大学 | 一种脑靶向hiv进入抑制剂多肽及其应用 |
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| KR102819567B1 (ko) * | 2021-11-24 | 2025-06-13 | 주식회사 윙스타바이오 | 아밀로이드 전구체 단백질에 대한 저해 활성을 갖는 펩타이드 및 이의 용도 |
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| WO2023143463A1 (en) * | 2022-01-30 | 2023-08-03 | Nanjing Reju Therapeutics , Inc. | Fusion protein and application thereof |
| CN119654336A (zh) * | 2022-05-16 | 2025-03-18 | 儿童医疗中心有限公司 | 治疗心脏病的组合物和方法 |
| CN115286694B (zh) * | 2022-06-02 | 2024-08-20 | 温州医科大学 | 一种南美青蛙宿主防御肽的衍生肽ps-pt-6f及其制备方法和应用 |
| CN115806740B (zh) * | 2022-11-17 | 2024-01-30 | 四川大学 | 一种集成多模态响应的导电水凝胶及其制备方法和用途 |
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| CN115948069B (zh) * | 2023-02-09 | 2024-11-29 | 广州工业智能研究院 | 一种双重抗菌超疏液涂层及其制备方法 |
| CN116298281A (zh) * | 2023-03-27 | 2023-06-23 | 山西农业大学 | 一种基于距离信号读出的胰蛋白酶含量检测方法 |
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| US20040052814A1 (en) * | 1998-09-28 | 2004-03-18 | Wenyuan Shi | Fusion proteins for targeted delivery of antimicrobial peptides |
| US20040162284A1 (en) * | 2003-02-19 | 2004-08-19 | Harris Herbert W. | Method of lowering body temperature with (S) tofisopam |
| RU2408605C2 (ru) * | 2005-02-18 | 2011-01-10 | Анджиокем Инк. | Полипептид, способный преодолевать гематоэнцефалический барьер, и его конъюгат |
| CN101511868B (zh) * | 2006-07-24 | 2013-03-06 | 比奥雷克西斯制药公司 | 毒蜥外泌肽融合蛋白 |
| AU2008255556B2 (en) * | 2007-05-29 | 2014-08-07 | Angiochem, Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
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2009
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2011
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-
2015
- 2015-04-24 US US14/696,193 patent/US20160263235A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201104497B (en) | 2012-09-26 |
| EP2794663A4 (en) | 2014-10-29 |
| CN103665170A (zh) | 2014-03-26 |
| US20160263235A1 (en) | 2016-09-15 |
| RU2011125366A (ru) | 2013-01-10 |
| CN102348723A (zh) | 2012-02-08 |
| WO2010063124A1 (en) | 2010-06-10 |
| US20110288011A1 (en) | 2011-11-24 |
| JP2012510798A (ja) | 2012-05-17 |
| EP2794663A1 (en) | 2014-10-29 |
| BRPI0923283A2 (pt) | 2017-06-06 |
| MX2011005964A (es) | 2011-09-01 |
| CA2745499A1 (en) | 2010-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |