AU2009283763B2 - HIG2 and URLC10 epitope peptide and vaccines containing the same - Google Patents

HIG2 and URLC10 epitope peptide and vaccines containing the same Download PDF

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Publication number
AU2009283763B2
AU2009283763B2 AU2009283763A AU2009283763A AU2009283763B2 AU 2009283763 B2 AU2009283763 B2 AU 2009283763B2 AU 2009283763 A AU2009283763 A AU 2009283763A AU 2009283763 A AU2009283763 A AU 2009283763A AU 2009283763 B2 AU2009283763 B2 AU 2009283763B2
Authority
AU
Australia
Prior art keywords
peptide
hla
cancer
antigen
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2009283763A
Other languages
English (en)
Other versions
AU2009283763A2 (en
AU2009283763A1 (en
Inventor
Ryuji Ohsawa
Takuya Tsunoda
Sachiko Yoshimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncotherapy Science Inc
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Publication of AU2009283763A1 publication Critical patent/AU2009283763A1/en
Publication of AU2009283763A2 publication Critical patent/AU2009283763A2/en
Application granted granted Critical
Publication of AU2009283763B2 publication Critical patent/AU2009283763B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2009283763A 2008-08-19 2009-08-14 HIG2 and URLC10 epitope peptide and vaccines containing the same Ceased AU2009283763B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8997208P 2008-08-19 2008-08-19
US61/089,972 2008-08-19
PCT/JP2009/003897 WO2010021112A1 (en) 2008-08-19 2009-08-14 Hig2 and urlc10 epitope peptide and vaccines containing the same

Publications (3)

Publication Number Publication Date
AU2009283763A1 AU2009283763A1 (en) 2010-02-25
AU2009283763A2 AU2009283763A2 (en) 2011-07-07
AU2009283763B2 true AU2009283763B2 (en) 2014-06-19

Family

ID=41707003

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009283763A Ceased AU2009283763B2 (en) 2008-08-19 2009-08-14 HIG2 and URLC10 epitope peptide and vaccines containing the same

Country Status (16)

Country Link
US (1) US9119800B2 (enExample)
EP (1) EP2328600B9 (enExample)
JP (1) JP5633025B2 (enExample)
KR (1) KR101713581B1 (enExample)
CN (2) CN102186491B (enExample)
AU (1) AU2009283763B2 (enExample)
BR (1) BRPI0917391A2 (enExample)
CA (1) CA2734467C (enExample)
DK (1) DK2328600T3 (enExample)
ES (1) ES2566011T3 (enExample)
IL (1) IL211117A (enExample)
MX (2) MX355054B (enExample)
RU (1) RU2529373C2 (enExample)
SG (2) SG10201610206VA (enExample)
TW (2) TWI580431B (enExample)
WO (1) WO2010021112A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI615403B (zh) * 2007-02-21 2018-02-21 腫瘤療法 科學股份有限公司 表現腫瘤相關抗原之癌症的胜肽疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
SMT201800444T1 (it) * 2010-11-17 2018-09-13 Aduro Biotech Inc Metodi e composizioni per indurre una risposta immunitaria contro egfrviii
JP6255594B2 (ja) 2012-07-10 2018-01-10 オンコセラピー・サイエンス株式会社 Ｔｈ１細胞のＬＹ６Ｋエピトープペプチドおよびこれを含有するワクチン
MX2017001651A (es) 2014-08-04 2017-04-27 Oncotherapy Science Inc Peptido derivado de urlc10 y vacuna que lo contiene.
MX392412B (es) 2015-08-10 2025-03-24 Toray Industries Polipéptidos que tienen actividad inductora de inmunidad.
RU2765574C2 (ru) 2015-08-12 2022-02-01 Онкотерапи Сайенс, Инк. Пептид, полученный из depdc1, и содержащая его вакцина
CN110741016A (zh) 2017-04-26 2020-01-31 优瑞科生物技术公司 嵌合抗体/t-细胞受体构筑体及其用途
PL3538645T3 (pl) 2017-06-20 2021-11-08 Institut Curie Komórki odpornościowe z defektem suv39h1
CN115300609A (zh) * 2021-05-08 2022-11-08 西湖大学 缺氧诱导脂滴相关蛋白(hilpda)在预防或治疗高血脂相关疾病中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006090810A2 (en) * 2005-02-25 2006-08-31 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
WO2008102557A1 (en) * 2007-02-21 2008-08-28 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
US20070014787A1 (en) 1998-07-15 2007-01-18 Human Genome Sciences, Inc. 71 human secreted proteins
ES2340357T3 (es) * 1999-08-05 2010-06-02 Green Peptide Co., Ltd. Antigeno tumoral.
WO2001023426A2 (en) 1999-09-30 2001-04-05 Varian Associates, Inc. Hypoxia-related human genes, proteins, and uses thereof
AU2002215345A1 (en) 2000-10-13 2002-04-22 Eos Biotechnology, Inc. Methods of diagnosis of prostate cancer, compositions and methods of screening for modulators of prostate cancer
US20030232350A1 (en) 2001-11-13 2003-12-18 Eos Biotechnology, Inc. Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
US20070015271A1 (en) 2002-04-04 2007-01-18 Rosen Craig A Human secreted proteins
US20060024692A1 (en) 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
WO2005019258A2 (en) 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
CN1882698B (zh) 2003-08-20 2011-05-25 肿瘤疗法科学股份有限公司 低氧可诱导的蛋白2(hig2)作为新的治疗肾细胞癌(rcc)的潜在标靶
JPWO2005123122A1 (ja) 2004-06-21 2008-04-10 株式会社グリーンペプタイド 癌治療ペプチドワクチン
EP2011885B1 (en) 2005-02-10 2015-04-22 Oncotherapy Science, Inc. Method of diagnosing bladder cancer
EP1854473A1 (en) 2005-03-03 2007-11-14 Takeda Pharmaceutical Company Limited Preventive/therapeutic agent for cancer
WO2007013575A2 (en) 2005-07-28 2007-02-01 Oncotherapy Science, Inc. Method for diagnosing and treating renal cell carcinoma
WO2007029778A1 (ja) 2005-09-07 2007-03-15 Nec Corporation Ｈｌａ結合性ペプチド、それをコードするｄｎａ断片および組み換えベクター
JP4840858B2 (ja) * 2006-03-16 2011-12-21 学校法人慶應義塾 癌ワクチン
ES2365077T3 (es) 2006-06-16 2011-09-21 Onco Therapy Science, Inc. Péptido antígeno anticáncer derivado de sparc y composición farmacéutica que comprende el mismo.
JP2010535014A (ja) 2007-07-30 2010-11-18 オンコセラピー・サイエンス株式会社 癌関連遺伝子ｌｙ６ｋ
TW201000115A (en) 2008-06-11 2010-01-01 Oncotherapy Science Inc IQGAP3 epitope peptides and vaccines containing the same
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006090810A2 (en) * 2005-02-25 2006-08-31 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
WO2008102557A1 (en) * 2007-02-21 2008-08-28 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SIDNEY J. ET AL: "Majority of peptides binding HLA-A*0201 with high affinity crossreact with other A2-supertype molecules", HUMAN IMMUNOLOGY, vol. 62, no. 11, November 2001, pages 1200-1216, pages 1648-1655 *
ZHU S. ET AL: "Improving MHC binding peptide prediction by incorporating binding data of auxiliary MHC molecules", BIOINFORMATICS (OXFORD), vol. 22, no. 13, July 2006 (2006-07), pages 1648- 1655 *

Also Published As

Publication number Publication date
ES2566011T3 (es) 2016-04-08
TWI580431B (zh) 2017-05-01
IL211117A (en) 2017-03-30
RU2011110376A (ru) 2012-09-27
IL211117A0 (en) 2011-04-28
KR101713581B1 (ko) 2017-03-08
CN104958753B (zh) 2018-09-25
TW201019952A (en) 2010-06-01
CA2734467C (en) 2017-10-03
EP2328600B9 (en) 2016-07-13
MX2011001883A (es) 2011-03-29
WO2010021112A1 (en) 2010-02-25
TW201500055A (zh) 2015-01-01
HK1157204A1 (zh) 2012-06-29
US9119800B2 (en) 2015-09-01
TWI543767B (zh) 2016-08-01
JP5633025B2 (ja) 2014-12-03
RU2529373C2 (ru) 2014-09-27
AU2009283763A2 (en) 2011-07-07
CN104958753A (zh) 2015-10-07
CN102186491B (zh) 2015-06-10
CN102186491A (zh) 2011-09-14
KR20110045052A (ko) 2011-05-03
AU2009283763A1 (en) 2010-02-25
US20110243973A1 (en) 2011-10-06
JP2012500184A (ja) 2012-01-05
CA2734467A1 (en) 2010-02-25
EP2328600B1 (en) 2016-01-27
MX355054B (es) 2018-04-03
MX337756B (es) 2016-03-17
DK2328600T3 (en) 2016-03-29
BRPI0917391A2 (pt) 2015-12-01
SG193806A1 (en) 2013-10-30
SG10201610206VA (en) 2017-01-27
EP2328600A4 (en) 2013-03-06
EP2328600A1 (en) 2011-06-08

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 16 JUN 2011

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired