AU2009283763B2 - HIG2 and URLC10 epitope peptide and vaccines containing the same - Google Patents

HIG2 and URLC10 epitope peptide and vaccines containing the same Download PDF

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Publication number
AU2009283763B2
AU2009283763B2 AU2009283763A AU2009283763A AU2009283763B2 AU 2009283763 B2 AU2009283763 B2 AU 2009283763B2 AU 2009283763 A AU2009283763 A AU 2009283763A AU 2009283763 A AU2009283763 A AU 2009283763A AU 2009283763 B2 AU2009283763 B2 AU 2009283763B2
Authority
AU
Australia
Prior art keywords
peptide
hla
cancer
antigen
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2009283763A
Other languages
English (en)
Other versions
AU2009283763A2 (en
AU2009283763A1 (en
Inventor
Ryuji Ohsawa
Takuya Tsunoda
Sachiko Yoshimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncotherapy Science Inc
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Publication of AU2009283763A1 publication Critical patent/AU2009283763A1/en
Publication of AU2009283763A2 publication Critical patent/AU2009283763A2/en
Application granted granted Critical
Publication of AU2009283763B2 publication Critical patent/AU2009283763B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2009283763A 2008-08-19 2009-08-14 HIG2 and URLC10 epitope peptide and vaccines containing the same Ceased AU2009283763B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8997208P 2008-08-19 2008-08-19
US61/089,972 2008-08-19
PCT/JP2009/003897 WO2010021112A1 (en) 2008-08-19 2009-08-14 Hig2 and urlc10 epitope peptide and vaccines containing the same

Publications (3)

Publication Number Publication Date
AU2009283763A1 AU2009283763A1 (en) 2010-02-25
AU2009283763A2 AU2009283763A2 (en) 2011-07-07
AU2009283763B2 true AU2009283763B2 (en) 2014-06-19

Family

ID=41707003

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009283763A Ceased AU2009283763B2 (en) 2008-08-19 2009-08-14 HIG2 and URLC10 epitope peptide and vaccines containing the same

Country Status (16)

Country Link
US (1) US9119800B2 (enExample)
EP (1) EP2328600B9 (enExample)
JP (1) JP5633025B2 (enExample)
KR (1) KR101713581B1 (enExample)
CN (2) CN102186491B (enExample)
AU (1) AU2009283763B2 (enExample)
BR (1) BRPI0917391A2 (enExample)
CA (1) CA2734467C (enExample)
DK (1) DK2328600T3 (enExample)
ES (1) ES2566011T3 (enExample)
IL (1) IL211117A (enExample)
MX (2) MX355054B (enExample)
RU (1) RU2529373C2 (enExample)
SG (2) SG10201610206VA (enExample)
TW (2) TWI543767B (enExample)
WO (1) WO2010021112A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI494319B (zh) * 2007-02-21 2015-08-01 Oncotherapy Science Inc 表現腫瘤相關抗原之癌症的胜肽疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
DK2640842T3 (en) * 2010-11-17 2018-08-13 Aduro Biotech Inc Methods and compositions for inducing an immune response to EGFRVIII
EP2872531A4 (en) 2012-07-10 2016-04-06 Oncotherapy Science Inc LY6K EPITOPE PEPTIDES FOR TH1 CELLS AND VACCINES CONTAINING SAME
US10576097B2 (en) * 2014-08-04 2020-03-03 Oncotherapy Science, Inc. URLC10-derived peptide and vaccine containing same
EP3335725B1 (en) 2015-08-10 2024-02-28 Toray Industries, Inc. Pds5a epitopes as immunity inducers
US10676508B2 (en) 2015-08-12 2020-06-09 Oncotherapy Science, Inc. DEPDC1-derived peptide and vaccine containing same
WO2018200582A1 (en) 2017-04-26 2018-11-01 Eureka Therapeutics, Inc. Chimeric antibody/t-cell receptor constructs and uses thereof
CN110997902B (zh) 2017-06-20 2021-11-30 居里研究所 Suv39h1缺陷的免疫细胞
CN115300609B (zh) * 2021-05-08 2026-07-28 西湖大学 缺氧诱导脂滴相关蛋白(hilpda)在预防或治疗高血脂相关疾病中的应用
CN120842356B (zh) * 2025-07-25 2026-07-17 广西医科大学附属肿瘤医院 Ly6k抗原表位肽、组合物及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006090810A2 (en) * 2005-02-25 2006-08-31 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
WO2008102557A1 (en) * 2007-02-21 2008-08-28 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
US20070014787A1 (en) 1998-07-15 2007-01-18 Human Genome Sciences, Inc. 71 human secreted proteins
ES2340357T3 (es) * 1999-08-05 2010-06-02 Green Peptide Co., Ltd. Antigeno tumoral.
AU7748200A (en) 1999-09-30 2001-04-30 Varian Associates, Inc. Hypoxia-related human genes, proteins, and uses thereof
EP1474528A4 (en) 2000-10-13 2006-06-14 Protein Design Labs Inc METHODS OF DIAGNOSIS OF PROSTATE CANCER, COMPOSITIONS AND METHODS OF EXAMINING PROSTATE CANCER MODULATORS
US20030232350A1 (en) 2001-11-13 2003-12-18 Eos Biotechnology, Inc. Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
US20070015271A1 (en) 2002-04-04 2007-01-18 Rosen Craig A Human secreted proteins
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US20060024692A1 (en) 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
WO2005019258A2 (en) 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
JP4614952B2 (ja) 2003-08-20 2011-01-19 オンコセラピー・サイエンス株式会社 腎細胞癌(rcc)の潜在的な新規治療標的としての低酸素誘導タンパク質2(hig2)
US20080286313A1 (en) 2004-06-21 2008-11-20 Kyogo Itoh Peptide Vaccines for the Treatment of Cancers
US7998695B2 (en) 2005-02-10 2011-08-16 Oncotherapy Science, Inc. Method of diagnosing bladder cancer
WO2006093337A1 (ja) 2005-03-03 2006-09-08 Takeda Pharmaceutical Company Limited 癌の予防・治療剤
EP1907580A2 (en) 2005-07-28 2008-04-09 Oncotherapy Science, Inc. Method for diagnosing and treating renal cell carcinoma
JP5116150B2 (ja) 2005-09-07 2013-01-09 日本電気株式会社 Hla結合性ペプチド、それをコードするdna断片および組み換えベクター
JP4840858B2 (ja) * 2006-03-16 2011-12-21 学校法人慶應義塾 癌ワクチン
RU2451521C2 (ru) * 2006-06-16 2012-05-27 Онкотерапи Сайенс, Инк. Sparc-производные антигенные пептиды отторжения опухоли и лекарственные средства, содержащие их
EP2185732A1 (en) 2007-07-30 2010-05-19 Oncotherapy Science, Inc. Cancer associated gene ly6k
TW201000115A (en) 2008-06-11 2010-01-01 Oncotherapy Science Inc IQGAP3 epitope peptides and vaccines containing the same
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006090810A2 (en) * 2005-02-25 2006-08-31 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
WO2008102557A1 (en) * 2007-02-21 2008-08-28 Oncotherapy Science, Inc. Peptide vaccines for cancers expressing tumor-associated antigens

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SIDNEY J. ET AL: "Majority of peptides binding HLA-A*0201 with high affinity crossreact with other A2-supertype molecules", HUMAN IMMUNOLOGY, vol. 62, no. 11, November 2001, pages 1200-1216, pages 1648-1655 *
ZHU S. ET AL: "Improving MHC binding peptide prediction by incorporating binding data of auxiliary MHC molecules", BIOINFORMATICS (OXFORD), vol. 22, no. 13, July 2006 (2006-07), pages 1648- 1655 *

Also Published As

Publication number Publication date
RU2529373C2 (ru) 2014-09-27
MX337756B (es) 2016-03-17
JP2012500184A (ja) 2012-01-05
US20110243973A1 (en) 2011-10-06
WO2010021112A1 (en) 2010-02-25
KR101713581B1 (ko) 2017-03-08
JP5633025B2 (ja) 2014-12-03
MX355054B (es) 2018-04-03
CN104958753B (zh) 2018-09-25
CA2734467A1 (en) 2010-02-25
IL211117A0 (en) 2011-04-28
BRPI0917391A2 (pt) 2015-12-01
MX2011001883A (es) 2011-03-29
TW201019952A (en) 2010-06-01
TW201500055A (zh) 2015-01-01
US9119800B2 (en) 2015-09-01
TWI543767B (zh) 2016-08-01
DK2328600T3 (en) 2016-03-29
EP2328600A1 (en) 2011-06-08
ES2566011T3 (es) 2016-04-08
TWI580431B (zh) 2017-05-01
SG193806A1 (en) 2013-10-30
AU2009283763A2 (en) 2011-07-07
KR20110045052A (ko) 2011-05-03
EP2328600B9 (en) 2016-07-13
AU2009283763A1 (en) 2010-02-25
HK1157204A1 (zh) 2012-06-29
EP2328600A4 (en) 2013-03-06
SG10201610206VA (en) 2017-01-27
CN104958753A (zh) 2015-10-07
RU2011110376A (ru) 2012-09-27
CN102186491A (zh) 2011-09-14
CA2734467C (en) 2017-10-03
EP2328600B1 (en) 2016-01-27
IL211117A (en) 2017-03-30
CN102186491B (zh) 2015-06-10

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 16 JUN 2011

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired