TWI580431B - Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 - Google Patents

Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 Download PDF

Info

Publication number
TWI580431B
TWI580431B TW103132024A TW103132024A TWI580431B TW I580431 B TWI580431 B TW I580431B TW 103132024 A TW103132024 A TW 103132024A TW 103132024 A TW103132024 A TW 103132024A TW I580431 B TWI580431 B TW I580431B
Authority
TW
Taiwan
Prior art keywords
peptide
antigen
hla
cancer
cytotoxic
Prior art date
Application number
TW103132024A
Other languages
English (en)
Chinese (zh)
Other versions
TW201500055A (zh
Inventor
角田卓也
大澤龍司
吉村祥子
Original Assignee
腫瘤療法 科學股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 腫瘤療法 科學股份有限公司 filed Critical 腫瘤療法 科學股份有限公司
Publication of TW201500055A publication Critical patent/TW201500055A/zh
Application granted granted Critical
Publication of TWI580431B publication Critical patent/TWI580431B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW103132024A 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 TWI580431B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8997208P 2008-08-19 2008-08-19

Publications (2)

Publication Number Publication Date
TW201500055A TW201500055A (zh) 2015-01-01
TWI580431B true TWI580431B (zh) 2017-05-01

Family

ID=41707003

Family Applications (2)

Application Number Title Priority Date Filing Date
TW103132024A TWI580431B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗
TW098127226A TWI543767B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW098127226A TWI543767B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗

Country Status (16)

Country Link
US (1) US9119800B2 (enExample)
EP (1) EP2328600B9 (enExample)
JP (1) JP5633025B2 (enExample)
KR (1) KR101713581B1 (enExample)
CN (2) CN102186491B (enExample)
AU (1) AU2009283763B2 (enExample)
BR (1) BRPI0917391A2 (enExample)
CA (1) CA2734467C (enExample)
DK (1) DK2328600T3 (enExample)
ES (1) ES2566011T3 (enExample)
IL (1) IL211117A (enExample)
MX (2) MX355054B (enExample)
RU (1) RU2529373C2 (enExample)
SG (2) SG10201610206VA (enExample)
TW (2) TWI580431B (enExample)
WO (1) WO2010021112A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI615403B (zh) * 2007-02-21 2018-02-21 腫瘤療法 科學股份有限公司 表現腫瘤相關抗原之癌症的胜肽疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
SMT201800444T1 (it) * 2010-11-17 2018-09-13 Aduro Biotech Inc Metodi e composizioni per indurre una risposta immunitaria contro egfrviii
JP6255594B2 (ja) 2012-07-10 2018-01-10 オンコセラピー・サイエンス株式会社 Th1細胞のLY6Kエピトープペプチドおよびこれを含有するワクチン
MX2017001651A (es) 2014-08-04 2017-04-27 Oncotherapy Science Inc Peptido derivado de urlc10 y vacuna que lo contiene.
MX392412B (es) 2015-08-10 2025-03-24 Toray Industries Polipéptidos que tienen actividad inductora de inmunidad.
RU2765574C2 (ru) 2015-08-12 2022-02-01 Онкотерапи Сайенс, Инк. Пептид, полученный из depdc1, и содержащая его вакцина
CN110741016A (zh) 2017-04-26 2020-01-31 优瑞科生物技术公司 嵌合抗体/t-细胞受体构筑体及其用途
PL3538645T3 (pl) 2017-06-20 2021-11-08 Institut Curie Komórki odpornościowe z defektem suv39h1
CN115300609A (zh) * 2021-05-08 2022-11-08 西湖大学 缺氧诱导脂滴相关蛋白(hilpda)在预防或治疗高血脂相关疾病中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020128201A1 (en) * 1999-08-05 2002-09-12 Kyogo Itoh Tumor antigen
WO2005019475A2 (en) * 2003-08-20 2005-03-03 Oncotherapy Science, Inc. Hypoxia-inducible protein 2 (hig2), a novel therapeutic potential target of renal cell carcinoma (rcc)
WO2006090810A2 (en) * 2005-02-25 2006-08-31 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
TW200844111A (en) * 2007-02-21 2008-11-16 Oncotherapy Science Inc Peptide vaccines for cancers expressing tumor-associated antigens

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070014787A1 (en) 1998-07-15 2007-01-18 Human Genome Sciences, Inc. 71 human secreted proteins
WO2001023426A2 (en) 1999-09-30 2001-04-05 Varian Associates, Inc. Hypoxia-related human genes, proteins, and uses thereof
AU2002215345A1 (en) 2000-10-13 2002-04-22 Eos Biotechnology, Inc. Methods of diagnosis of prostate cancer, compositions and methods of screening for modulators of prostate cancer
US20030232350A1 (en) 2001-11-13 2003-12-18 Eos Biotechnology, Inc. Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
US20070015271A1 (en) 2002-04-04 2007-01-18 Rosen Craig A Human secreted proteins
US20060024692A1 (en) 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
WO2005019258A2 (en) 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
JPWO2005123122A1 (ja) 2004-06-21 2008-04-10 株式会社グリーンペプタイド 癌治療ペプチドワクチン
EP2011885B1 (en) 2005-02-10 2015-04-22 Oncotherapy Science, Inc. Method of diagnosing bladder cancer
EP1854473A1 (en) 2005-03-03 2007-11-14 Takeda Pharmaceutical Company Limited Preventive/therapeutic agent for cancer
WO2007013575A2 (en) 2005-07-28 2007-02-01 Oncotherapy Science, Inc. Method for diagnosing and treating renal cell carcinoma
WO2007029778A1 (ja) 2005-09-07 2007-03-15 Nec Corporation Hla結合性ペプチド、それをコードするdna断片および組み換えベクター
JP4840858B2 (ja) * 2006-03-16 2011-12-21 学校法人慶應義塾 癌ワクチン
ES2365077T3 (es) 2006-06-16 2011-09-21 Onco Therapy Science, Inc. Péptido antígeno anticáncer derivado de sparc y composición farmacéutica que comprende el mismo.
JP2010535014A (ja) 2007-07-30 2010-11-18 オンコセラピー・サイエンス株式会社 癌関連遺伝子ly6k
TW201000115A (en) 2008-06-11 2010-01-01 Oncotherapy Science Inc IQGAP3 epitope peptides and vaccines containing the same
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020128201A1 (en) * 1999-08-05 2002-09-12 Kyogo Itoh Tumor antigen
WO2005019475A2 (en) * 2003-08-20 2005-03-03 Oncotherapy Science, Inc. Hypoxia-inducible protein 2 (hig2), a novel therapeutic potential target of renal cell carcinoma (rcc)
WO2006090810A2 (en) * 2005-02-25 2006-08-31 Oncotherapy Science, Inc. Peptide vaccines for lung cancers expressing ttk, urlc10 or koc1 polypeptides
TW200844111A (en) * 2007-02-21 2008-11-16 Oncotherapy Science Inc Peptide vaccines for cancers expressing tumor-associated antigens

Also Published As

Publication number Publication date
ES2566011T3 (es) 2016-04-08
IL211117A (en) 2017-03-30
RU2011110376A (ru) 2012-09-27
IL211117A0 (en) 2011-04-28
KR101713581B1 (ko) 2017-03-08
CN104958753B (zh) 2018-09-25
TW201019952A (en) 2010-06-01
CA2734467C (en) 2017-10-03
EP2328600B9 (en) 2016-07-13
MX2011001883A (es) 2011-03-29
WO2010021112A1 (en) 2010-02-25
TW201500055A (zh) 2015-01-01
HK1157204A1 (zh) 2012-06-29
US9119800B2 (en) 2015-09-01
TWI543767B (zh) 2016-08-01
JP5633025B2 (ja) 2014-12-03
RU2529373C2 (ru) 2014-09-27
AU2009283763A2 (en) 2011-07-07
CN104958753A (zh) 2015-10-07
CN102186491B (zh) 2015-06-10
AU2009283763B2 (en) 2014-06-19
CN102186491A (zh) 2011-09-14
KR20110045052A (ko) 2011-05-03
AU2009283763A1 (en) 2010-02-25
US20110243973A1 (en) 2011-10-06
JP2012500184A (ja) 2012-01-05
CA2734467A1 (en) 2010-02-25
EP2328600B1 (en) 2016-01-27
MX355054B (es) 2018-04-03
MX337756B (es) 2016-03-17
DK2328600T3 (en) 2016-03-29
BRPI0917391A2 (pt) 2015-12-01
SG193806A1 (en) 2013-10-30
SG10201610206VA (en) 2017-01-27
EP2328600A4 (en) 2013-03-06
EP2328600A1 (en) 2011-06-08

Similar Documents

Publication Publication Date Title
TWI526219B (zh) Cdca1抗原決定位胜肽及含此胜肽的疫苗
TWI580431B (zh) Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗
US20110280898A1 (en) Inhbb epitope peptides and vaccines containing the same
US9675680B2 (en) MELK epitope peptides and vaccines containing the same
CN102119170A (zh) Mybl2表位肽及包含它的疫苗
TWI500932B (zh) Wdrpuh抗原決定位胜肽以及含此胜肽之疫苗
HK1157204B (en) Hig2 and urlc10 epitope peptide and vaccines containing the same
HK1155757A (en) Cdca1 epitope peptides and vaccines containing the same
HK1155757B (en) Cdca1 epitope peptides and vaccines containing the same

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees