AU2009281809B2 - Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions - Google Patents

Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions Download PDF

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Publication number
AU2009281809B2
AU2009281809B2 AU2009281809A AU2009281809A AU2009281809B2 AU 2009281809 B2 AU2009281809 B2 AU 2009281809B2 AU 2009281809 A AU2009281809 A AU 2009281809A AU 2009281809 A AU2009281809 A AU 2009281809A AU 2009281809 B2 AU2009281809 B2 AU 2009281809B2
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mesenchymal stem
mscs
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AU2009281809A1 (en
Inventor
Alla Danilkovich
Robert E. Newman
Samson Tom
Christopher Ton
Zhanling Wang
Randal Young
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Mesoblast International SARL
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Mesoblast International SARL
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Publication of AU2009281809A1 publication Critical patent/AU2009281809A1/en
Assigned to Mesoblast International Sarl reassignment Mesoblast International Sarl Request for Assignment Assignors: OSIRIS THERAPEUTICS, INC.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2009281809A 2008-08-14 2009-08-14 Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions Active AU2009281809B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2015268673A AU2015268673B2 (en) 2008-08-14 2015-12-11 Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions
AU2017268526A AU2017268526A1 (en) 2008-08-14 2017-11-28 Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8889808P 2008-08-14 2008-08-14
US61/088,898 2008-08-14
PCT/US2009/053891 WO2010019886A1 (en) 2008-08-14 2009-08-14 Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions

Related Child Applications (1)

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AU2015268673A Division AU2015268673B2 (en) 2008-08-14 2015-12-11 Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions

Publications (2)

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AU2009281809A1 AU2009281809A1 (en) 2010-02-18
AU2009281809B2 true AU2009281809B2 (en) 2015-09-17

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AU2009281809A Active AU2009281809B2 (en) 2008-08-14 2009-08-14 Purified mesenchymal stem cell compositions and methods of purifying mesenchymal stem cell compositions

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US (6) US8637004B2 (cg-RX-API-DMAC7.html)
EP (3) EP4477742A3 (cg-RX-API-DMAC7.html)
JP (7) JP6025329B2 (cg-RX-API-DMAC7.html)
AR (2) AR073069A1 (cg-RX-API-DMAC7.html)
AU (1) AU2009281809B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0917993B8 (cg-RX-API-DMAC7.html)
CA (1) CA2733985C (cg-RX-API-DMAC7.html)
DK (1) DK2318519T3 (cg-RX-API-DMAC7.html)
ES (1) ES2608974T3 (cg-RX-API-DMAC7.html)
IL (1) IL211214A0 (cg-RX-API-DMAC7.html)
MX (2) MX362512B (cg-RX-API-DMAC7.html)
NZ (2) NZ602248A (cg-RX-API-DMAC7.html)
WO (1) WO2010019886A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201101858B (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
US20230089901A1 (en) 2023-03-23
US8637004B2 (en) 2014-01-28
ZA201101858B (en) 2011-11-30
US20100068191A1 (en) 2010-03-18
AR123811A2 (es) 2023-01-18
MX362512B (es) 2019-01-22
AU2009281809A1 (en) 2010-02-18
US20250312379A1 (en) 2025-10-09
MX2011001730A (es) 2011-03-24
DK2318519T3 (en) 2017-01-16
EP4477742A2 (en) 2024-12-18
NZ602248A (en) 2014-03-28
JP2023052211A (ja) 2023-04-11
EP2318519B1 (en) 2016-10-05
JP2018109052A (ja) 2018-07-12
EP3124601A1 (en) 2017-02-01
BRPI0917993B8 (pt) 2021-05-25
JP2015071610A (ja) 2015-04-16
CA2733985C (en) 2016-07-12
US20180008642A1 (en) 2018-01-11
JP2020120671A (ja) 2020-08-13
JP2025122125A (ja) 2025-08-20
IL211214A0 (en) 2011-04-28
BRPI0917993B1 (pt) 2020-12-29
EP4477742A3 (en) 2025-02-26
CA2733985A1 (en) 2010-02-18
JP2017081972A (ja) 2017-05-18
BRPI0917993A2 (pt) 2017-10-10
ES2608974T3 (es) 2017-04-17
NZ591146A (en) 2012-10-26
EP2318519A1 (en) 2011-05-11
US20140105872A1 (en) 2014-04-17
JP2012500214A (ja) 2012-01-05
EP2318519A4 (en) 2013-07-24
WO2010019886A1 (en) 2010-02-18
JP6025329B2 (ja) 2016-11-16
JP7580202B2 (ja) 2024-11-11
AR073069A1 (es) 2010-10-13
US20200197444A1 (en) 2020-06-25

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