AU2009220244B2 - Contrast agents for applications including perfusion imaging - Google Patents

Contrast agents for applications including perfusion imaging Download PDF

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Publication number
AU2009220244B2
AU2009220244B2 AU2009220244A AU2009220244A AU2009220244B2 AU 2009220244 B2 AU2009220244 B2 AU 2009220244B2 AU 2009220244 A AU2009220244 A AU 2009220244A AU 2009220244 A AU2009220244 A AU 2009220244A AU 2009220244 B2 AU2009220244 B2 AU 2009220244B2
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imaging
imaging moiety
alkyl
alkoxyalkyl
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AU2009220244A1 (en
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David S. Casebier
Mikhail Kagan
Joel Lazewatsky
Simon P. Robinson
Ming Yu
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Lantheus Medical Imaging Inc
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Lantheus Medical Imaging Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2009220244A 2008-02-29 2009-02-27 Contrast agents for applications including perfusion imaging Active AU2009220244B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2015200027A AU2015200027B2 (en) 2008-02-29 2015-01-06 Contrast agents for applications including perfusion imaging

Applications Claiming Priority (3)

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US6759308P 2008-02-29 2008-02-29
US61/067,593 2008-02-29
PCT/US2009/001247 WO2009110984A2 (en) 2008-02-29 2009-02-27 Contrast agents for applications including perfusion imaging

Related Child Applications (1)

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AU2015200027A Division AU2015200027B2 (en) 2008-02-29 2015-01-06 Contrast agents for applications including perfusion imaging

Publications (2)

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AU2009220244A1 AU2009220244A1 (en) 2009-09-11
AU2009220244B2 true AU2009220244B2 (en) 2014-10-09

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US (2) US9408927B2 (enExample)
EP (1) EP2257315B1 (enExample)
JP (3) JP5946992B2 (enExample)
KR (1) KR101616139B1 (enExample)
CN (1) CN102014969B (enExample)
AU (1) AU2009220244B2 (enExample)
CA (2) CA2716354C (enExample)
DK (1) DK2257315T3 (enExample)
ES (1) ES2767973T3 (enExample)
IL (1) IL207853A (enExample)
PT (1) PT2257315T (enExample)
WO (2) WO2009108376A2 (enExample)

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US7485283B2 (en) * 2004-04-28 2009-02-03 Lantheus Medical Imaging Contrast agents for myocardial perfusion imaging
ES2767973T3 (es) 2008-02-29 2020-06-19 Lantheus Medical Imaging Inc Agentes de contraste para aplicaciones que comprenden formación de imágenes de perfusión
US20100241001A1 (en) * 2009-03-20 2010-09-23 Palmeri Mark L Ultrasound Methods, Systems and Computer Program Products for Imaging Fluids
DK2419096T3 (da) * 2009-04-15 2020-02-03 Lantheus Medical Imaging Inc Stabilisering af radiofarmaceutiske sammensætninger under anvendelse af ascorbinsyre
AU2011213568B2 (en) * 2010-02-08 2016-05-12 Lantheus Medical Imaging, Inc. Methods and apparatus for synthesizing imaging agents, and intermediates thereof
CA3123737A1 (en) 2011-09-09 2013-03-14 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
CA2852395C (en) * 2011-10-21 2020-04-28 Lantheus Medical Imaging, Inc. Compositions comprising ascorbic acid and pyridaben and pyridaben analogs attached to an imaging moiety and related methods
CN103254140B (zh) * 2012-02-17 2016-02-17 北京师范大学 新型18f标记取代喹唑啉类化合物及其制备方法和肿瘤pet显像应用
SG10201608370TA (en) 2012-04-10 2016-11-29 Lantheus Medical Imaging Inc Radiopharmaceutical synthesis methods
AU2013203000B9 (en) * 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
CN104718299B (zh) * 2012-08-13 2024-02-06 通用医院公司 用于线粒体复合物i的定量定位的系统和方法
WO2014030709A1 (ja) 2012-08-24 2014-02-27 浜松ホトニクス株式会社 ミトコンドリアComplex-1の検出に適した化合物
EP4296364B1 (en) 2013-12-03 2025-12-03 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
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GB201805253D0 (en) 2018-03-29 2018-05-16 Ge Healthcare Ltd Ip Solid phase extraction
CN110305010B (zh) * 2019-07-17 2022-05-13 江苏中旗科技股份有限公司 一种2,5-二甲基苯乙酸的制备方法
WO2023013757A1 (ja) * 2021-08-05 2023-02-09 積水メディカル株式会社 アルキルシリルオキシ置換ベンジル化合物の製造方法
WO2024132895A1 (en) * 2022-12-19 2024-06-27 Syngenta Crop Protection Ag Microbiocidal dihydrooxadiazinyl pyridazinone compounds

Citations (2)

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Publication number Priority date Publication date Assignee Title
US20050191238A1 (en) * 2004-02-13 2005-09-01 Casebier David S. Contrast agents for myocardial perfusion imaging
US20070036716A1 (en) * 2005-08-10 2007-02-15 Casebier David S Methods of making radiolabeled tracers and precursors thereof

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Publication number Publication date
CN102014969B (zh) 2014-07-09
US20110091374A1 (en) 2011-04-21
JP2015061842A (ja) 2015-04-02
CN102014969A (zh) 2011-04-13
WO2009108376A2 (en) 2009-09-03
AU2009220244A1 (en) 2009-09-11
JP2011513306A (ja) 2011-04-28
JP5922207B2 (ja) 2016-05-24
US20160361448A1 (en) 2016-12-15
US9408927B2 (en) 2016-08-09
WO2009110984A2 (en) 2009-09-11
CA2967254A1 (en) 2009-09-11
US20180133347A9 (en) 2018-05-17
KR101616139B1 (ko) 2016-04-27
WO2009108376A3 (en) 2009-11-19
PT2257315T (pt) 2020-01-27
EP2257315A4 (en) 2013-04-17
JP5946992B2 (ja) 2016-07-06
CA2967254C (en) 2019-03-26
DK2257315T3 (da) 2020-01-27
EP2257315B1 (en) 2019-10-23
IL207853A (en) 2015-05-31
CA2716354A1 (en) 2009-09-11
EP2257315A2 (en) 2010-12-08
KR20100121530A (ko) 2010-11-17
ES2767973T3 (es) 2020-06-19
JP2016164182A (ja) 2016-09-08
WO2009110984A3 (en) 2009-12-10
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IL207853A0 (en) 2010-12-30
US10245332B2 (en) 2019-04-02

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