AU2008204433B2 - Anti-KIR antibodies, formulations, and uses thereof - Google Patents
Anti-KIR antibodies, formulations, and uses thereof Download PDFInfo
- Publication number
- AU2008204433B2 AU2008204433B2 AU2008204433A AU2008204433A AU2008204433B2 AU 2008204433 B2 AU2008204433 B2 AU 2008204433B2 AU 2008204433 A AU2008204433 A AU 2008204433A AU 2008204433 A AU2008204433 A AU 2008204433A AU 2008204433 B2 AU2008204433 B2 AU 2008204433B2
- Authority
- AU
- Australia
- Prior art keywords
- kir
- antibody
- formulation
- patient
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013237638A AU2013237638B2 (en) | 2007-01-11 | 2013-10-01 | Anti-kir antibodies, formulations, and uses thereof |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87996407P | 2007-01-11 | 2007-01-11 | |
| US60/879,964 | 2007-01-11 | ||
| US91152707P | 2007-04-13 | 2007-04-13 | |
| US60/911,527 | 2007-04-13 | ||
| PCT/EP2008/050306 WO2008084106A1 (en) | 2007-01-11 | 2008-01-11 | Anti-kir antibodies, formulations, and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013237638A Division AU2013237638B2 (en) | 2007-01-11 | 2013-10-01 | Anti-kir antibodies, formulations, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2008204433A1 AU2008204433A1 (en) | 2008-07-17 |
| AU2008204433B2 true AU2008204433B2 (en) | 2014-03-13 |
Family
ID=39144327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008204433A Ceased AU2008204433B2 (en) | 2007-01-11 | 2008-01-11 | Anti-KIR antibodies, formulations, and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20100189723A1 (enExample) |
| EP (2) | EP2604278B1 (enExample) |
| JP (3) | JP5478261B2 (enExample) |
| CN (2) | CN101578113B (enExample) |
| AU (1) | AU2008204433B2 (enExample) |
| CA (1) | CA2675291C (enExample) |
| ES (2) | ES2627923T3 (enExample) |
| WO (1) | WO2008084106A1 (enExample) |
Families Citing this family (77)
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| KR20060079180A (ko) | 2003-07-02 | 2006-07-05 | 노보 노르디스크 에이/에스 | Nk 세포 활성을 조절하기 위한 조성물 및 방법 |
| US20090191213A9 (en) * | 2003-07-02 | 2009-07-30 | Novo Nordisk A/S | Compositions and methods for regulating NK cell activity |
| EP1835929B8 (en) * | 2005-01-06 | 2016-07-27 | Novo Nordisk A/S | Anti-kir combination treatments and methods |
| WO2010065939A1 (en) | 2008-12-05 | 2010-06-10 | Indiana University Research & Technology Corporation | Combination therapy to enhace nk cell mediated cytotoxicty |
| FI3604510T3 (fi) | 2009-03-30 | 2025-06-26 | Alexion Pharma Inc | Vastalääkkeitä tekijä xa:n estäjille ja menetelmiä niiden käyttämiseksi |
| PT2453910T (pt) * | 2009-07-15 | 2016-12-07 | Portola Pharm Inc | Formulação de dose unitária de antídoto contra inibidores de fator xa para uso na prevenção de sangramento |
| EP2630158B1 (en) * | 2010-10-22 | 2018-12-12 | Dana-Farber Cancer Institute, Inc. | Discovery of regulatory t cells programmed to suppress an immune response |
| CA2818684C (en) * | 2010-11-22 | 2023-02-21 | Innate Pharma Sa | Nk cell modulating treatments and methods for treatment of hematological malignancies |
| KR20120093002A (ko) * | 2011-02-14 | 2012-08-22 | (주)에이티젠 | Nk 세포의 활성 측정을 이용한 암 진단 방법 및 진단 키트 |
| AU2012260601B2 (en) | 2011-05-25 | 2018-02-01 | Innate Pharma, S.A. | Anti-KIR antibodies for the treatment of inflammatory disorders |
| EP2904011B1 (en) * | 2012-10-02 | 2017-08-23 | Bristol-Myers Squibb Company | Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer |
| CA2906101A1 (en) * | 2013-03-15 | 2014-09-18 | Bayer Healthcare Llc | Anti-prolactin receptor antibody formulations |
| WO2015069785A1 (en) | 2013-11-06 | 2015-05-14 | Bristol-Myers Squibb Company | Combination of anti-kir and anti-cs1 antibodies to treat multiple myeloma |
| ES2772307T3 (es) | 2014-10-28 | 2020-07-07 | Childrens Univ Hospital Tuebingen | Tratamiento de pacientes pediátricos con LLA-PCB con un anticuerpo anti-kir |
| SG11201708223QA (en) | 2015-04-17 | 2017-11-29 | Bristol Myers Squibb Co | Compositions comprising a combination of an anti-pd-1 antibody and another antibody |
| RU2017142352A (ru) | 2015-05-06 | 2019-06-06 | Снипр Текнолоджиз Лимитед | Изменение популяций микроорганизмов и модификация микробиоты |
| KR101997241B1 (ko) | 2015-05-21 | 2019-07-09 | 하푼 테라퓨틱스, 인크. | 삼중특이성 결합 단백질 및 사용 방법 |
| CN116196426A (zh) | 2015-07-16 | 2023-06-02 | 百欧肯治疗有限公司 | 治疗癌症的组合物及方法 |
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Citations (3)
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| WO2005003172A2 (en) * | 2003-07-02 | 2005-01-13 | Innate Pharma | Pan-kir2dl nk-receptor antibodies and their use in diagnostik and therapy |
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| US20060280740A1 (en) * | 2003-07-02 | 2006-12-14 | Novo Nordisk A/S | Compositions and methods for regulating NK cell activity |
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| AU2012260601B2 (en) * | 2011-05-25 | 2018-02-01 | Innate Pharma, S.A. | Anti-KIR antibodies for the treatment of inflammatory disorders |
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2008
- 2008-01-11 US US12/521,105 patent/US20100189723A1/en not_active Abandoned
- 2008-01-11 WO PCT/EP2008/050306 patent/WO2008084106A1/en not_active Ceased
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- 2008-01-11 JP JP2009545192A patent/JP5478261B2/ja not_active Expired - Fee Related
- 2008-01-11 EP EP13159380.8A patent/EP2604278B1/en active Active
- 2008-01-11 CN CN200880002001.2A patent/CN101578113B/zh active Active
- 2008-01-11 EP EP08707869.7A patent/EP2109460B1/en active Active
- 2008-01-11 ES ES13159380.8T patent/ES2627923T3/es active Active
- 2008-01-11 ES ES08707869.7T patent/ES2579768T3/es active Active
- 2008-01-11 AU AU2008204433A patent/AU2008204433B2/en not_active Ceased
- 2008-01-11 CN CN201510142726.3A patent/CN105037549B/zh active Active
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2013
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2015
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- 2015-11-20 JP JP2015227492A patent/JP2016104728A/ja active Pending
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2017
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| WO2005003172A2 (en) * | 2003-07-02 | 2005-01-13 | Innate Pharma | Pan-kir2dl nk-receptor antibodies and their use in diagnostik and therapy |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2604278A1 (en) | 2013-06-19 |
| JP5478261B2 (ja) | 2014-04-23 |
| EP2604278B1 (en) | 2017-04-12 |
| US20180208652A1 (en) | 2018-07-26 |
| EP2109460B1 (en) | 2016-05-18 |
| JP2014050393A (ja) | 2014-03-20 |
| CN105037549B (zh) | 2018-09-28 |
| CN105037549A (zh) | 2015-11-11 |
| JP2016104728A (ja) | 2016-06-09 |
| JP6223771B2 (ja) | 2017-11-01 |
| WO2008084106A1 (en) | 2008-07-17 |
| US9879082B2 (en) | 2018-01-30 |
| AU2008204433A1 (en) | 2008-07-17 |
| WO2008084106A9 (en) | 2009-09-17 |
| JP2010515709A (ja) | 2010-05-13 |
| CN101578113B (zh) | 2015-04-22 |
| US20100189723A1 (en) | 2010-07-29 |
| CA2675291C (en) | 2017-05-23 |
| CN101578113A (zh) | 2009-11-11 |
| EP2109460A1 (en) | 2009-10-21 |
| CA2675291A1 (en) | 2008-07-17 |
| ES2627923T3 (es) | 2017-08-01 |
| US10815299B2 (en) | 2020-10-27 |
| US20150197569A1 (en) | 2015-07-16 |
| ES2579768T3 (es) | 2016-08-16 |
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