CA2675291C - Killer ig-like receptor (kir) antibodies, formulations, and uses thereof - Google Patents
Killer ig-like receptor (kir) antibodies, formulations, and uses thereof Download PDFInfo
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- CA2675291C CA2675291C CA2675291A CA2675291A CA2675291C CA 2675291 C CA2675291 C CA 2675291C CA 2675291 A CA2675291 A CA 2675291A CA 2675291 A CA2675291 A CA 2675291A CA 2675291 C CA2675291 C CA 2675291C
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87996407P | 2007-01-11 | 2007-01-11 | |
| US60/879,964 | 2007-01-11 | ||
| US91152707P | 2007-04-13 | 2007-04-13 | |
| US60/911,527 | 2007-04-13 | ||
| PCT/EP2008/050306 WO2008084106A1 (en) | 2007-01-11 | 2008-01-11 | Anti-kir antibodies, formulations, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
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| CA2675291A1 CA2675291A1 (en) | 2008-07-17 |
| CA2675291C true CA2675291C (en) | 2017-05-23 |
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Family Applications (1)
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|---|---|---|---|
| CA2675291A Active CA2675291C (en) | 2007-01-11 | 2008-01-11 | Killer ig-like receptor (kir) antibodies, formulations, and uses thereof |
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| Country | Link |
|---|---|
| US (3) | US20100189723A1 (enExample) |
| EP (2) | EP2109460B1 (enExample) |
| JP (3) | JP5478261B2 (enExample) |
| CN (2) | CN101578113B (enExample) |
| AU (1) | AU2008204433B2 (enExample) |
| CA (1) | CA2675291C (enExample) |
| ES (2) | ES2627923T3 (enExample) |
| WO (1) | WO2008084106A1 (enExample) |
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| US20090191213A9 (en) * | 2003-07-02 | 2009-07-30 | Novo Nordisk A/S | Compositions and methods for regulating NK cell activity |
| EP1639013B1 (en) | 2003-07-02 | 2012-09-12 | Innate Pharma | Pan-kir2dl NK-receptor antibodies and their use in diagnostic and therapy |
| ES2732623T3 (es) * | 2005-01-06 | 2019-11-25 | Innate Pharma Sa | Tratamientos y métodos de combinación anti-KIR |
| US8709411B2 (en) | 2008-12-05 | 2014-04-29 | Novo Nordisk A/S | Combination therapy to enhance NK cell mediated cytotoxicity |
| FI3604510T3 (fi) | 2009-03-30 | 2025-06-26 | Alexion Pharma Inc | Vastalääkkeitä tekijä xa:n estäjille ja menetelmiä niiden käyttämiseksi |
| ES2605801T3 (es) | 2009-07-15 | 2017-03-16 | Portola Pharmaceuticals, Inc. | Formulación de dosis unitaria de antídoto para inhibidores del factor Xa para su uso en la prevención de la hemorragia |
| JP2014502258A (ja) * | 2010-10-22 | 2014-01-30 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | 免疫反応を抑制するためにプログラムされた制御性ｔ細胞の発見 |
| TWI664191B (zh) * | 2010-11-22 | 2019-07-01 | 天賜製藥公司 | Ｎｋ細胞調節治療及治療血液惡性疾病之方法 |
| KR20120093002A (ko) * | 2011-02-14 | 2012-08-22 | (주)에이티젠 | Ｎｋ 세포의 활성 측정을 이용한 암 진단 방법 및 진단 키트 |
| BR112013030017A2 (pt) | 2011-05-25 | 2020-10-13 | Innate Pharma Sa | anticorpos anti-kir para o tratamento de distúrbios inflamatórios |
| HUE035503T2 (en) | 2012-10-02 | 2018-05-02 | Bristol Myers Squibb Co | Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer |
| AR095496A1 (es) * | 2013-03-15 | 2015-10-21 | Bayer Healthcare Llc | Formulaciones de anticuerpos anti-receptor de prolactina |
| US10494433B2 (en) | 2013-11-06 | 2019-12-03 | Bristol-Myers Squibb Company | Combination of anti-KIR and anti-CS1 antibodies to treat multiple myeloma |
| US11639384B2 (en) | 2014-10-28 | 2023-05-02 | University Children's Hospital Tübingen | Treatment of pediatric BCP-ALL patients with an anti-KIR antibody |
| MA53243A (fr) | 2015-04-17 | 2021-06-23 | Bristol Myers Squibb Co | Compositions comprenant une combinaison de ipilimumab et nivolumab |
| EP3291679B1 (en) | 2015-05-06 | 2021-12-15 | SNIPR Technologies Limited | Altering microbial populations & modifying microbiota |
| WO2016187594A1 (en) | 2015-05-21 | 2016-11-24 | Harpoon Therapeutics, Inc. | Trispecific binding proteins and methods of use |
| EP3744340A3 (en) | 2015-07-16 | 2021-03-03 | Biokine Therapeutics Ltd. | Compositions and methods for treating cancer |
| US20190038713A1 (en) | 2015-11-07 | 2019-02-07 | Multivir Inc. | Compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer |
| CN108350416A (zh) | 2015-11-09 | 2018-07-31 | 百时美施贵宝公司 | 操纵在cho细胞中产生的多肽的品质属性的方法 |
| BR112018017195A2 (pt) * | 2016-02-24 | 2019-01-02 | Children's Hospital Of Eastern Ontario Research Institute Inc. | terapia de combinação de smc para o tratamento do câncer |
| PT4019019T (pt) | 2016-05-20 | 2024-05-13 | Biohaven Therapeutics Ltd | Utilização de riluzol, profármacos de riluzol ou análogos de riluzol com imunoterapêuticas para tratar o cancro |
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| CN105037549A (zh) | 2015-11-11 |
| CN101578113B (zh) | 2015-04-22 |
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