ES2627923T3 - Anticuerpos anti-KIR, formulaciones y usos de los mismos - Google Patents
Anticuerpos anti-KIR, formulaciones y usos de los mismos Download PDFInfo
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- ES2627923T3 ES2627923T3 ES13159380.8T ES13159380T ES2627923T3 ES 2627923 T3 ES2627923 T3 ES 2627923T3 ES 13159380 T ES13159380 T ES 13159380T ES 2627923 T3 ES2627923 T3 ES 2627923T3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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Landscapes
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| US20090191213A9 (en) * | 2003-07-02 | 2009-07-30 | Novo Nordisk A/S | Compositions and methods for regulating NK cell activity |
| EP1835929B8 (en) * | 2005-01-06 | 2016-07-27 | Novo Nordisk A/S | Anti-kir combination treatments and methods |
| WO2010065939A1 (en) | 2008-12-05 | 2010-06-10 | Indiana University Research & Technology Corporation | Combination therapy to enhace nk cell mediated cytotoxicty |
| FI3604510T3 (fi) | 2009-03-30 | 2025-06-26 | Alexion Pharma Inc | Vastalääkkeitä tekijä xa:n estäjille ja menetelmiä niiden käyttämiseksi |
| PT2453910T (pt) * | 2009-07-15 | 2016-12-07 | Portola Pharm Inc | Formulação de dose unitária de antídoto contra inibidores de fator xa para uso na prevenção de sangramento |
| EP2630158B1 (en) * | 2010-10-22 | 2018-12-12 | Dana-Farber Cancer Institute, Inc. | Discovery of regulatory t cells programmed to suppress an immune response |
| CA2818684C (en) * | 2010-11-22 | 2023-02-21 | Innate Pharma Sa | Nk cell modulating treatments and methods for treatment of hematological malignancies |
| KR20120093002A (ko) * | 2011-02-14 | 2012-08-22 | (주)에이티젠 | Nk 세포의 활성 측정을 이용한 암 진단 방법 및 진단 키트 |
| AU2012260601B2 (en) | 2011-05-25 | 2018-02-01 | Innate Pharma, S.A. | Anti-KIR antibodies for the treatment of inflammatory disorders |
| EP2904011B1 (en) * | 2012-10-02 | 2017-08-23 | Bristol-Myers Squibb Company | Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer |
| CA2906101A1 (en) * | 2013-03-15 | 2014-09-18 | Bayer Healthcare Llc | Anti-prolactin receptor antibody formulations |
| WO2015069785A1 (en) | 2013-11-06 | 2015-05-14 | Bristol-Myers Squibb Company | Combination of anti-kir and anti-cs1 antibodies to treat multiple myeloma |
| ES2772307T3 (es) | 2014-10-28 | 2020-07-07 | Childrens Univ Hospital Tuebingen | Tratamiento de pacientes pediátricos con LLA-PCB con un anticuerpo anti-kir |
| SG11201708223QA (en) | 2015-04-17 | 2017-11-29 | Bristol Myers Squibb Co | Compositions comprising a combination of an anti-pd-1 antibody and another antibody |
| RU2017142352A (ru) | 2015-05-06 | 2019-06-06 | Снипр Текнолоджиз Лимитед | Изменение популяций микроорганизмов и модификация микробиоты |
| KR101997241B1 (ko) | 2015-05-21 | 2019-07-09 | 하푼 테라퓨틱스, 인크. | 삼중특이성 결합 단백질 및 사용 방법 |
| CN116196426A (zh) | 2015-07-16 | 2023-06-02 | 百欧肯治疗有限公司 | 治疗癌症的组合物及方法 |
| EP3371221A2 (en) | 2015-11-07 | 2018-09-12 | MultiVir Inc. | Methods and compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer |
| JP2018536404A (ja) | 2015-11-09 | 2018-12-13 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | Cho細胞において産生したポリペプチドの品質特性を操作する方法 |
| EP3419643A4 (en) * | 2016-02-24 | 2020-04-01 | Children's Hospital of Eastern Ontario Research Institute Inc. | SMC-BASED ANTI-CANCER THERAPY |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| JP7169195B2 (ja) | 2016-05-20 | 2022-11-10 | バイオヘイブン・ファーマシューティカル・ホールディング・カンパニー・リミテッド | 癌を処置するためのリルゾール、リルゾールプロドラッグまたはリルゾール類似体と免疫療法との併用 |
| GB201609811D0 (en) | 2016-06-05 | 2016-07-20 | Snipr Technologies Ltd | Methods, cells, systems, arrays, RNA and kits |
| BR112019006041A2 (pt) | 2016-09-27 | 2019-09-03 | Board Of Regents, The University Of Texas System | métodos para aprimorar a terapia de bloqueio do ponto de verificação imunológico por modulação do microbioma |
| RU2755903C2 (ru) | 2016-10-12 | 2021-09-22 | Борд Оф Риджентс, Дзе Юниверсити Оф Техас Систем | Способы и композиции для tusc2-иммунотерапии |
| KR20190112263A (ko) | 2016-12-12 | 2019-10-04 | 멀티비르 인코포레이티드 | 암 및 감염성 질환의 치료 및 예방을 위한 바이러스 유전자 치료요법 및 면역 체크포인트 억제제를 포함하는 방법 및 조성물 |
| AU2018243754B2 (en) | 2017-03-31 | 2025-04-10 | Bristol-Myers Squibb Company | Methods of treating tumor |
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| AU2019322487B2 (en) | 2018-03-19 | 2024-04-18 | Multivir Inc. | Methods and compositions comprising tumor suppressor gene therapy and CD122/CD132 agonists for the treatment of cancer |
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| GB2301366B (en) | 1994-03-29 | 1998-07-29 | Celltech Therapeutics Ltd | Antibodies against E-selectin |
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| US20040152632A1 (en) * | 2002-11-06 | 2004-08-05 | Wyeth | Combination therapy for the treatment of acute leukemia and myelodysplastic syndrome |
| CN1852924A (zh) * | 2003-07-02 | 2006-10-25 | 依奈特制药公司 | Pan-kir2dl nk-受体的抗体及其在诊断及治疗中的应用 |
| KR20060079180A (ko) * | 2003-07-02 | 2006-07-05 | 노보 노르디스크 에이/에스 | Nk 세포 활성을 조절하기 위한 조성물 및 방법 |
| US20090191213A9 (en) * | 2003-07-02 | 2009-07-30 | Novo Nordisk A/S | Compositions and methods for regulating NK cell activity |
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| EA009873B1 (ru) * | 2004-02-06 | 2008-04-28 | Элан Фармасьютикалз, Инк. | Способ ингибирования роста опухоли и/или метастатического прогрессирования |
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| WO2010065939A1 (en) * | 2008-12-05 | 2010-06-10 | Indiana University Research & Technology Corporation | Combination therapy to enhace nk cell mediated cytotoxicty |
| AU2012260601B2 (en) * | 2011-05-25 | 2018-02-01 | Innate Pharma, S.A. | Anti-KIR antibodies for the treatment of inflammatory disorders |
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| JP5478261B2 (ja) | 2014-04-23 |
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| WO2008084106A9 (en) | 2009-09-17 |
| JP2010515709A (ja) | 2010-05-13 |
| CN101578113B (zh) | 2015-04-22 |
| US20100189723A1 (en) | 2010-07-29 |
| CA2675291C (en) | 2017-05-23 |
| CN101578113A (zh) | 2009-11-11 |
| EP2109460A1 (en) | 2009-10-21 |
| CA2675291A1 (en) | 2008-07-17 |
| US10815299B2 (en) | 2020-10-27 |
| US20150197569A1 (en) | 2015-07-16 |
| ES2579768T3 (es) | 2016-08-16 |
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