ES2627923T3 - Anticuerpos anti-KIR, formulaciones y usos de los mismos - Google Patents
Anticuerpos anti-KIR, formulaciones y usos de los mismos Download PDFInfo
- Publication number
- ES2627923T3 ES2627923T3 ES13159380.8T ES13159380T ES2627923T3 ES 2627923 T3 ES2627923 T3 ES 2627923T3 ES 13159380 T ES13159380 T ES 13159380T ES 2627923 T3 ES2627923 T3 ES 2627923T3
- Authority
- ES
- Spain
- Prior art keywords
- kir
- antibody
- formulation
- dose
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87996407P | 2007-01-11 | 2007-01-11 | |
| US879964P | 2007-01-11 | ||
| US91152707P | 2007-04-13 | 2007-04-13 | |
| US911527P | 2007-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2627923T3 true ES2627923T3 (es) | 2017-08-01 |
Family
ID=39144327
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13159380.8T Active ES2627923T3 (es) | 2007-01-11 | 2008-01-11 | Anticuerpos anti-KIR, formulaciones y usos de los mismos |
| ES08707869.7T Active ES2579768T3 (es) | 2007-01-11 | 2008-01-11 | Anticuerpos anti-KIR, formulaciones y usos de los mismos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08707869.7T Active ES2579768T3 (es) | 2007-01-11 | 2008-01-11 | Anticuerpos anti-KIR, formulaciones y usos de los mismos |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20100189723A1 (enExample) |
| EP (2) | EP2109460B1 (enExample) |
| JP (3) | JP5478261B2 (enExample) |
| CN (2) | CN105037549B (enExample) |
| AU (1) | AU2008204433B2 (enExample) |
| CA (1) | CA2675291C (enExample) |
| ES (2) | ES2627923T3 (enExample) |
| WO (1) | WO2008084106A1 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090191213A9 (en) * | 2003-07-02 | 2009-07-30 | Novo Nordisk A/S | Compositions and methods for regulating NK cell activity |
| KR101444717B1 (ko) | 2003-07-02 | 2014-09-26 | 노보 노르디스크 에이/에스 | Nk 세포 활성을 조절하기 위한 조성물 및 방법 |
| WO2006072625A2 (en) * | 2005-01-06 | 2006-07-13 | Novo Nordisk A/S | Anti-kir combination treatments and methods |
| EP2367553B1 (en) * | 2008-12-05 | 2017-05-03 | Novo Nordisk A/S | Combination therapy to enhance nk cell mediated cytotoxicity |
| LT3604510T (lt) | 2009-03-30 | 2025-07-10 | Alexion Pharmaceuticals, Inc. | Faktoriaus xa inhibitorius neutralizuojančios medžiagos ir jų naudojimo būdai |
| JP6163304B2 (ja) * | 2009-07-15 | 2017-07-12 | ポートラ ファーマシューティカルズ, インコーポレイテッド | 第Xa因子インヒビターの解毒剤の単位用量処方物およびその使用方法 |
| JP2014502258A (ja) * | 2010-10-22 | 2014-01-30 | ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド | 免疫反応を抑制するためにプログラムされた制御性t細胞の発見 |
| BR112013012138B1 (pt) * | 2010-11-22 | 2022-02-22 | Innate Pharma Sa | Uso de um composto que inibe um receptor inibidor de célula natural killer (nkcir) |
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| ES2765874T3 (es) | 2011-05-25 | 2020-06-11 | Innate Pharma Sa | Anticuerpos anti-KIR para el tratamiento de trastornos inflamatorios |
| LT2904011T (lt) * | 2012-10-02 | 2017-11-10 | Bristol-Myers Squibb Company | Anti-kir antikūnų ir anti-pd-1 antikūnų derinys, akirtas vėžio gydymui |
| JP2016515515A (ja) * | 2013-03-15 | 2016-05-30 | バイエル・ヘルスケア・エルエルシーBayer HealthCare LLC | 抗プロラクチン受容体抗体製剤 |
| ES2707057T3 (es) * | 2013-11-06 | 2019-04-02 | Bristol Myers Squibb Co | Combinación de anticuerpos anti-KIR y anti-CS1 para tratar el mieloma múltiple |
| ES2772307T3 (es) | 2014-10-28 | 2020-07-07 | Childrens Univ Hospital Tuebingen | Tratamiento de pacientes pediátricos con LLA-PCB con un anticuerpo anti-kir |
| MY188749A (en) | 2015-04-17 | 2021-12-28 | Bristol Myers Squibb Co | Compositions comprising a combination of nivolumab and ipilimumab |
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| MX383614B (es) | 2015-05-21 | 2025-03-14 | Harpoon Therapeutics Inc | Proteinas de union triespecificas y metodos de uso. |
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| AU2016349632A1 (en) | 2015-11-07 | 2018-05-24 | Multivir Inc. | Compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer |
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| JP5112863B2 (ja) * | 2004-07-01 | 2013-01-09 | ノヴォ ノルディスク アー/エス | ヒト抗−kir抗体 |
| CN101444071B (zh) * | 2004-10-29 | 2013-03-13 | Hid环球公司 | 使用安全消耗品供应的证件生产 |
| ES2374603T3 (es) * | 2005-01-06 | 2012-02-20 | Novo Nordisk A/S | Agentes de unión a kir y procedimientos de uso de los mismos. |
| WO2006116369A2 (en) * | 2005-04-22 | 2006-11-02 | Genentech, Inc. | Method for treating dementia or alzheimer's disease with a cd20 antibody |
| EP2367553B1 (en) * | 2008-12-05 | 2017-05-03 | Novo Nordisk A/S | Combination therapy to enhance nk cell mediated cytotoxicity |
| ES2765874T3 (es) * | 2011-05-25 | 2020-06-11 | Innate Pharma Sa | Anticuerpos anti-KIR para el tratamiento de trastornos inflamatorios |
-
2008
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- 2008-01-11 ES ES13159380.8T patent/ES2627923T3/es active Active
- 2008-01-11 CA CA2675291A patent/CA2675291C/en active Active
- 2008-01-11 ES ES08707869.7T patent/ES2579768T3/es active Active
- 2008-01-11 JP JP2009545192A patent/JP5478261B2/ja not_active Expired - Fee Related
- 2008-01-11 AU AU2008204433A patent/AU2008204433B2/en not_active Ceased
- 2008-01-11 WO PCT/EP2008/050306 patent/WO2008084106A1/en not_active Ceased
- 2008-01-11 EP EP08707869.7A patent/EP2109460B1/en not_active Not-in-force
- 2008-01-11 EP EP13159380.8A patent/EP2604278B1/en not_active Not-in-force
- 2008-01-11 CN CN201510142726.3A patent/CN105037549B/zh not_active Expired - Fee Related
- 2008-01-11 CN CN200880002001.2A patent/CN101578113B/zh not_active Expired - Fee Related
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2013
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2017
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Also Published As
| Publication number | Publication date |
|---|---|
| US20100189723A1 (en) | 2010-07-29 |
| CN105037549A (zh) | 2015-11-11 |
| AU2008204433B2 (en) | 2014-03-13 |
| US20150197569A1 (en) | 2015-07-16 |
| JP2016104728A (ja) | 2016-06-09 |
| JP2010515709A (ja) | 2010-05-13 |
| ES2579768T3 (es) | 2016-08-16 |
| WO2008084106A1 (en) | 2008-07-17 |
| WO2008084106A9 (en) | 2009-09-17 |
| JP6223771B2 (ja) | 2017-11-01 |
| CN101578113A (zh) | 2009-11-11 |
| CN101578113B (zh) | 2015-04-22 |
| AU2008204433A1 (en) | 2008-07-17 |
| US10815299B2 (en) | 2020-10-27 |
| CA2675291A1 (en) | 2008-07-17 |
| EP2109460A1 (en) | 2009-10-21 |
| CA2675291C (en) | 2017-05-23 |
| JP5478261B2 (ja) | 2014-04-23 |
| US9879082B2 (en) | 2018-01-30 |
| EP2109460B1 (en) | 2016-05-18 |
| US20180208652A1 (en) | 2018-07-26 |
| EP2604278A1 (en) | 2013-06-19 |
| EP2604278B1 (en) | 2017-04-12 |
| JP2014050393A (ja) | 2014-03-20 |
| CN105037549B (zh) | 2018-09-28 |
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