AU2007215363A1 - Use of gallium(III) complexes for the treatment of melanomas - Google Patents
Use of gallium(III) complexes for the treatment of melanomas Download PDFInfo
- Publication number
- AU2007215363A1 AU2007215363A1 AU2007215363A AU2007215363A AU2007215363A1 AU 2007215363 A1 AU2007215363 A1 AU 2007215363A1 AU 2007215363 A AU2007215363 A AU 2007215363A AU 2007215363 A AU2007215363 A AU 2007215363A AU 2007215363 A1 AU2007215363 A1 AU 2007215363A1
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- Australia
- Prior art keywords
- compound according
- cycloalkyl
- alkyl
- aryl
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 201000001441 melanoma Diseases 0.000 title claims description 15
- 150000002258 gallium Chemical class 0.000 title description 15
- 150000001875 compounds Chemical class 0.000 claims description 33
- 125000003118 aryl group Chemical group 0.000 claims description 26
- 125000000217 alkyl group Chemical group 0.000 claims description 15
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 14
- 125000001072 heteroaryl group Chemical group 0.000 claims description 14
- 239000003814 drug Substances 0.000 claims description 13
- 125000000623 heterocyclic group Chemical group 0.000 claims description 9
- GYHNNYVSQQEPJS-UHFFFAOYSA-N Gallium Chemical compound [Ga] GYHNNYVSQQEPJS-UHFFFAOYSA-N 0.000 claims description 8
- 229910052733 gallium Inorganic materials 0.000 claims description 7
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- 239000001257 hydrogen Substances 0.000 claims description 3
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- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 1
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- VXNZUUAINFGPBY-UHFFFAOYSA-N 1-Butene Chemical group CCC=C VXNZUUAINFGPBY-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- ASYYOZSDALANRF-UHFFFAOYSA-K 3-bis[(2-methyl-4-oxopyran-3-yl)oxy]gallanyloxy-2-methylpyran-4-one Chemical compound [Ga+3].CC=1OC=CC(=O)C=1[O-].CC=1OC=CC(=O)C=1[O-].CC=1OC=CC(=O)C=1[O-] ASYYOZSDALANRF-UHFFFAOYSA-K 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
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- IYABWNGZIDDRAK-UHFFFAOYSA-N allene Chemical group C=C=C IYABWNGZIDDRAK-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
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- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 description 1
- 150000002259 gallium compounds Chemical class 0.000 description 1
- UPWPDUACHOATKO-UHFFFAOYSA-K gallium trichloride Chemical compound Cl[Ga](Cl)Cl UPWPDUACHOATKO-UHFFFAOYSA-K 0.000 description 1
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- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
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- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 description 1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013206221A AU2013206221A1 (en) | 2006-02-13 | 2013-06-07 | Use of gallium (III) complexes for the treatment of melanomas |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0022006A AT503317B1 (de) | 2006-02-13 | 2006-02-13 | Verwendung von gallium(iii)-komplexen zur herstellung eines medikaments zur behandlung von melanomen |
| ATA220/2006 | 2006-02-13 | ||
| PCT/AT2007/000071 WO2007092978A1 (de) | 2006-02-13 | 2007-02-13 | Verwendung von gallium (iii) komplexen zur behandlung von melanomen |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013206221A Division AU2013206221A1 (en) | 2006-02-13 | 2013-06-07 | Use of gallium (III) complexes for the treatment of melanomas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2007215363A1 true AU2007215363A1 (en) | 2007-08-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007215363A Abandoned AU2007215363A1 (en) | 2006-02-13 | 2007-02-13 | Use of gallium(III) complexes for the treatment of melanomas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7919486B2 (enExample) |
| EP (1) | EP1984005B1 (enExample) |
| JP (1) | JP5210888B2 (enExample) |
| CN (1) | CN101466387A (enExample) |
| AT (2) | AT503317B1 (enExample) |
| AU (1) | AU2007215363A1 (enExample) |
| CA (1) | CA2640509C (enExample) |
| DE (1) | DE502007006880D1 (enExample) |
| ES (1) | ES2365028T3 (enExample) |
| NZ (1) | NZ571119A (enExample) |
| PT (1) | PT1984005E (enExample) |
| WO (1) | WO2007092978A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101783676B1 (ko) | 2010-02-12 | 2017-10-10 | 니키 파머 액퀴지션 코포레이션 2 | 혈액암의 치료 방법 |
| ES2527358T3 (es) * | 2010-02-26 | 2015-01-22 | Niiki Pharma Inc. | Compuesto para el tratamiento de cáncer cerebral |
| CN102946879B (zh) * | 2010-04-19 | 2015-04-22 | 尼基制药公司 | 一种蛋白酶体抑制剂和镓络合物在制备治疗增殖性疾病的药物中的应用 |
| JP6112512B2 (ja) * | 2010-12-01 | 2017-04-12 | レクシ ファーマ インコーポレイテッド | 難治性癌を治療するための方法 |
| CN113372269A (zh) * | 2021-06-25 | 2021-09-10 | 云南大学 | 一种席夫碱镓配合物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0599881B1 (en) * | 1991-07-25 | 1998-05-13 | Philippe Collery | Gallium (iii) complexes, process for their obtention and pharmaceutical compositions containing them |
| DE10113185A1 (de) * | 2001-03-19 | 2002-10-24 | Faustus Forschungs Cie | Zusammensetzung, enthaltend einen Gallium(III)-Komplex und einen therapeutisch wirksamen Platin-Komplex |
| DE10116527C2 (de) * | 2001-04-03 | 2003-05-15 | Faustus Forschungs Cie | Tumorhemmende Galliumverbindungen, deren Verwendung als Arzneimittel sowie ein Arzneimittel, diese enthaltend |
| AT501819B1 (de) * | 2005-04-18 | 2007-01-15 | Faustus Forschung Translationa | Verwendung von gallium(iii)-komplexen zur behandlung von tumorerkrankungen der leber |
-
2006
- 2006-02-13 AT AT0022006A patent/AT503317B1/de not_active IP Right Cessation
-
2007
- 2007-02-13 AU AU2007215363A patent/AU2007215363A1/en not_active Abandoned
- 2007-02-13 CN CNA2007800127458A patent/CN101466387A/zh active Pending
- 2007-02-13 JP JP2008553574A patent/JP5210888B2/ja not_active Expired - Fee Related
- 2007-02-13 CA CA2640509A patent/CA2640509C/en not_active Expired - Fee Related
- 2007-02-13 AT AT07701315T patent/ATE504307T1/de active
- 2007-02-13 DE DE502007006880T patent/DE502007006880D1/de active Active
- 2007-02-13 PT PT07701315T patent/PT1984005E/pt unknown
- 2007-02-13 NZ NZ571119A patent/NZ571119A/en not_active IP Right Cessation
- 2007-02-13 ES ES07701315T patent/ES2365028T3/es active Active
- 2007-02-13 WO PCT/AT2007/000071 patent/WO2007092978A1/de not_active Ceased
- 2007-02-13 EP EP07701315A patent/EP1984005B1/de active Active
-
2008
- 2008-08-13 US US12/190,759 patent/US7919486B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101466387A (zh) | 2009-06-24 |
| AT503317B1 (de) | 2007-09-15 |
| JP5210888B2 (ja) | 2013-06-12 |
| PT1984005E (pt) | 2011-07-11 |
| JP2009525987A (ja) | 2009-07-16 |
| ES2365028T3 (es) | 2011-09-20 |
| NZ571119A (en) | 2011-11-25 |
| US20090137620A1 (en) | 2009-05-28 |
| CA2640509A1 (en) | 2007-08-23 |
| WO2007092978A1 (de) | 2007-08-23 |
| CA2640509C (en) | 2014-07-08 |
| EP1984005B1 (de) | 2011-04-06 |
| EP1984005A1 (de) | 2008-10-29 |
| DE502007006880D1 (de) | 2011-05-19 |
| ATE504307T1 (de) | 2011-04-15 |
| AT503317A4 (de) | 2007-09-15 |
| US7919486B2 (en) | 2011-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: NIIKI PHARMA, INC. Free format text: FORMER APPLICANT(S): FAUSTUS FORSCHUNG TRANSLATIONAL DRUG DEVELOPMENT AG |
|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |