AU2007206769B2 - Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. liguriae - Google Patents

Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. liguriae Download PDF

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Publication number
AU2007206769B2
AU2007206769B2 AU2007206769A AU2007206769A AU2007206769B2 AU 2007206769 B2 AU2007206769 B2 AU 2007206769B2 AU 2007206769 A AU2007206769 A AU 2007206769A AU 2007206769 A AU2007206769 A AU 2007206769A AU 2007206769 B2 AU2007206769 B2 AU 2007206769B2
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AU
Australia
Prior art keywords
actagardine
gene
polypeptide
ala
seq
Prior art date
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Ceased
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AU2007206769A
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AU2007206769A1 (en
Inventor
Steven Boakes
Jesus Cortes Bargallo
Michael John Dawson
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Novacta Biosystems Ltd
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Novacta Biosystems Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2007206769A 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. liguriae Ceased AU2007206769B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0600928.6 2006-01-17
GBGB0600928.6A GB0600928D0 (en) 2006-01-17 2006-01-17 Improvements relating to lantibiotics
PCT/GB2007/000138 WO2007083112A2 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from a. garbadinensis and a. liguriae

Publications (2)

Publication Number Publication Date
AU2007206769A1 AU2007206769A1 (en) 2007-07-26
AU2007206769B2 true AU2007206769B2 (en) 2013-06-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007206769A Ceased AU2007206769B2 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. liguriae

Country Status (20)

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US (3) USRE45003E1 (US07794700-20100914-C00152.png)
EP (2) EP2189472A1 (US07794700-20100914-C00152.png)
JP (1) JP5219837B2 (US07794700-20100914-C00152.png)
KR (1) KR101573536B1 (US07794700-20100914-C00152.png)
CN (1) CN101389641B (US07794700-20100914-C00152.png)
AT (1) ATE534659T1 (US07794700-20100914-C00152.png)
AU (1) AU2007206769B2 (US07794700-20100914-C00152.png)
BR (1) BRPI0706525A2 (US07794700-20100914-C00152.png)
CA (1) CA2637315A1 (US07794700-20100914-C00152.png)
CY (1) CY1112559T1 (US07794700-20100914-C00152.png)
DK (1) DK1979375T3 (US07794700-20100914-C00152.png)
ES (1) ES2378090T3 (US07794700-20100914-C00152.png)
GB (1) GB0600928D0 (US07794700-20100914-C00152.png)
IL (1) IL192446A0 (US07794700-20100914-C00152.png)
MX (1) MX2008009047A (US07794700-20100914-C00152.png)
NZ (1) NZ569486A (US07794700-20100914-C00152.png)
PL (1) PL1979375T3 (US07794700-20100914-C00152.png)
PT (1) PT1979375E (US07794700-20100914-C00152.png)
SI (1) SI1979375T1 (US07794700-20100914-C00152.png)
WO (1) WO2007083112A2 (US07794700-20100914-C00152.png)

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GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
GB0714029D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
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CN102348718B (zh) * 2009-01-14 2015-06-03 诺瓦克塔生物系统有限公司 去氧阿肽加定衍生物
GB0900599D0 (en) 2009-01-14 2009-02-18 Novacta Biosystems Ltd Treatment
EP2393829A1 (en) 2009-02-04 2011-12-14 Novacta Biosystems Limited Actagardine derivatives
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GB201001688D0 (en) 2010-02-02 2010-03-17 Novacta Biosystems Ltd Compounds
CN103052383A (zh) * 2010-07-14 2013-04-17 诺瓦克塔生物系统有限公司 含有b型羊毛硫抗生素的制剂
GB201013507D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
GB201013513D0 (en) * 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
GB201013508D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
GB201013509D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
WO2014085637A1 (en) * 2012-11-30 2014-06-05 Sentinella Pharmaceuticals, Inc. New lantibiotic derivatives and a process for their preparation
CN103483433B (zh) * 2013-09-10 2015-05-27 中国科学院微生物研究所 一种新型高效的羊毛硫细菌素cerecidin及其应用
CN106188253B (zh) * 2016-08-26 2020-08-18 上海交通大学 抗菌肽Lexapeptide及其制备方法和用途

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Also Published As

Publication number Publication date
US20100048459A1 (en) 2010-02-25
EP1979375B9 (en) 2012-05-09
US8465947B2 (en) 2013-06-18
US20110306091A1 (en) 2011-12-15
JP5219837B2 (ja) 2013-06-26
MX2008009047A (es) 2008-12-18
WO2007083112A3 (en) 2008-05-08
US7989416B2 (en) 2011-08-02
EP2189472A1 (en) 2010-05-26
BRPI0706525A2 (pt) 2011-03-29
AU2007206769A1 (en) 2007-07-26
PT1979375E (pt) 2012-03-06
EP1979375B1 (en) 2011-11-23
DK1979375T3 (da) 2012-03-19
USRE45003E1 (en) 2014-07-08
CN101389641B (zh) 2013-06-05
CN101389641A (zh) 2009-03-18
KR20080086517A (ko) 2008-09-25
EP1979375A2 (en) 2008-10-15
CY1112559T1 (el) 2016-02-10
GB0600928D0 (en) 2006-02-22
IL192446A0 (en) 2008-12-29
CA2637315A1 (en) 2007-07-26
JP2009523777A (ja) 2009-06-25
PL1979375T3 (pl) 2012-04-30
ES2378090T3 (es) 2012-04-04
NZ569486A (en) 2011-07-29
ATE534659T1 (de) 2011-12-15
SI1979375T1 (sl) 2012-03-30
KR101573536B1 (ko) 2015-12-11
WO2007083112A2 (en) 2007-07-26

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired