AU2006315580A1 - Method of treating ovarian and renal cancer using antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen - Google Patents

Method of treating ovarian and renal cancer using antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen Download PDF

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Publication number
AU2006315580A1
AU2006315580A1 AU2006315580A AU2006315580A AU2006315580A1 AU 2006315580 A1 AU2006315580 A1 AU 2006315580A1 AU 2006315580 A AU2006315580 A AU 2006315580A AU 2006315580 A AU2006315580 A AU 2006315580A AU 2006315580 A1 AU2006315580 A1 AU 2006315580A1
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Australia
Prior art keywords
tim
antibody
antibodies
cells
seq
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Abandoned
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AU2006315580A
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English (en)
Inventor
Michael E. Jeffers
William J. Larochelle
Henri Lichenstein
John Macdougall
Traci Mansfield
Vincent A. Pollack
Suresh G. Shenoy
Kam Fai Tse
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CuraGen Corp
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CuraGen Corp
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Publication date
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Publication of AU2006315580A1 publication Critical patent/AU2006315580A1/en
Priority to AU2013206293A priority Critical patent/AU2013206293B2/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
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    • A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
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    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
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    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/106—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from kidney or bladder
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/3038—Kidney, bladder
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants

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  • Engineering & Computer Science (AREA)
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  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Urology & Nephrology (AREA)
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  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
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  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Optics & Photonics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
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  • Gynecology & Obstetrics (AREA)
AU2006315580A 2005-11-10 2006-11-13 Method of treating ovarian and renal cancer using antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen Abandoned AU2006315580A1 (en)

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EP1957115A4 (en) 2010-02-10
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JP2009515897A (ja) 2009-04-16
JP2013127007A (ja) 2013-06-27
CA2629453A1 (en) 2007-05-24
US20130202527A1 (en) 2013-08-08
EP2548583A2 (en) 2013-01-23
WO2007059082A1 (en) 2007-05-24
EP1957115A1 (en) 2008-08-20
EP1957115B1 (en) 2014-01-15
US20170267750A1 (en) 2017-09-21
JP2014240430A (ja) 2014-12-25

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