AU2006312714A1 - Diaryl urea for treating pulmonary hypertension - Google Patents

Diaryl urea for treating pulmonary hypertension Download PDF

Info

Publication number
AU2006312714A1
AU2006312714A1 AU2006312714A AU2006312714A AU2006312714A1 AU 2006312714 A1 AU2006312714 A1 AU 2006312714A1 AU 2006312714 A AU2006312714 A AU 2006312714A AU 2006312714 A AU2006312714 A AU 2006312714A AU 2006312714 A1 AU2006312714 A1 AU 2006312714A1
Authority
AU
Australia
Prior art keywords
compound
formula
combination
pulmonary hypertension
pulmonary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006312714A
Other languages
English (en)
Inventor
Joachim Hutter
Martina Klein
Bernd Riedl
Peter Sandner
Hanna Tinel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of AU2006312714A1 publication Critical patent/AU2006312714A1/en
Assigned to BAYER SCHERING PHARMA AKTIENGESELLSCHAFT reassignment BAYER SCHERING PHARMA AKTIENGESELLSCHAFT Request for Assignment Assignors: BAYER HEALTHCARE AG
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2006312714A 2005-11-10 2006-10-30 Diaryl urea for treating pulmonary hypertension Abandoned AU2006312714A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP05024509.1 2005-11-10
EP05024509 2005-11-10
EP05027450.5 2005-12-15
EP05027450 2005-12-15
EP06012234.8 2006-06-14
EP06012234 2006-06-14
PCT/EP2006/010406 WO2007054216A1 (en) 2005-11-10 2006-10-30 Diaryl urea for treating pulmonary hypertension

Publications (1)

Publication Number Publication Date
AU2006312714A1 true AU2006312714A1 (en) 2007-05-18

Family

ID=37622057

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006312714A Abandoned AU2006312714A1 (en) 2005-11-10 2006-10-30 Diaryl urea for treating pulmonary hypertension

Country Status (18)

Country Link
US (1) US20100035888A1 (https=)
EP (1) EP1948170A1 (https=)
JP (1) JP5084736B2 (https=)
KR (1) KR20080067000A (https=)
AR (1) AR057849A1 (https=)
AU (1) AU2006312714A1 (https=)
BR (1) BRPI0618522A2 (https=)
CA (1) CA2628849A1 (https=)
CR (1) CR9953A (https=)
EC (1) ECSP088430A (https=)
GT (1) GT200800058A (https=)
IL (1) IL191178A0 (https=)
NO (1) NO20082498L (https=)
PE (1) PE20070806A1 (https=)
SV (1) SV2009002900A (https=)
TW (1) TW200733961A (https=)
UY (1) UY29903A1 (https=)
WO (1) WO2007054216A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
ATE538794T1 (de) * 1999-01-13 2012-01-15 Bayer Healthcare Llc Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
US20080108672A1 (en) * 2002-01-11 2008-05-08 Bernd Riedl Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
MXPA04007832A (es) 2002-02-11 2005-09-08 Bayer Pharmaceuticals Corp Aril-ureas con actividad inhibitoria de angiogenesis.
DE202004021759U1 (de) * 2003-02-21 2010-10-07 ResMed Ltd., Bella Vista Nasale Anordnung
US7557129B2 (en) * 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
WO2004113274A2 (en) * 2003-05-20 2004-12-29 Bayer Pharmaceuticals Corporation Diaryl ureas with kinase inhibiting activity
EA010485B1 (ru) 2003-07-23 2008-10-30 Байер Фамэсьютиклс Копэрейшн Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты)
KR101381454B1 (ko) * 2004-09-29 2014-04-04 바이엘 인텔렉쳐 프로퍼티 게엠베하 열역학적으로 안정한 형태의 bay 43-9006 토실레이트
AR062927A1 (es) * 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
JP5885012B2 (ja) * 2007-01-19 2016-03-15 バイエル・ヘルスケア・エルエルシーBayer HealthCareLLC Kit阻害剤に対して獲得した抵抗性を有する癌の処置
JP2011525503A (ja) * 2008-06-25 2011-09-22 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト 心不全を処置するためのジアリールウレア
CA2796744A1 (en) * 2010-04-17 2011-10-20 Bayer Healthcare Llc Synthetic metabolites of fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
MA34553B1 (fr) 2010-10-01 2013-09-02 Bayer Ip Gmbh Combinaisons contenant du n-(2-arylamino)arylsulfonamide substitué
US20140127295A1 (en) * 2011-03-14 2014-05-08 Cellworks Group, Inc Compositions, process of preparation of said compositions and method of treating inflammatory diseases
US20160317542A1 (en) 2013-12-09 2016-11-03 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04007832A (es) * 2002-02-11 2005-09-08 Bayer Pharmaceuticals Corp Aril-ureas con actividad inhibitoria de angiogenesis.
WO2003084543A1 (en) * 2002-04-10 2003-10-16 Virginia Commonwealth University Combination of glivec(sti571) with a cyclin-dependent kinase inhibitor, especially flavopiridol in the treatment of cancer
WO2004113274A2 (en) * 2003-05-20 2004-12-29 Bayer Pharmaceuticals Corporation Diaryl ureas with kinase inhibiting activity
EA010485B1 (ru) * 2003-07-23 2008-10-30 Байер Фамэсьютиклс Копэрейшн Производное n,n'-дифенилмочевины, фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с его использованием (варианты)
WO2006091542A2 (en) * 2005-02-22 2006-08-31 Cedars-Sinai Medical Center Use of sildenafil, vardenafil and other 5-phosphodiesterase inhibitors to enhance permeability of the abnormal blood-brain barrier

Also Published As

Publication number Publication date
GT200800058A (es) 2010-02-23
JP5084736B2 (ja) 2012-11-28
KR20080067000A (ko) 2008-07-17
CR9953A (es) 2008-10-08
UY29903A1 (es) 2007-06-29
AR057849A1 (es) 2007-12-19
US20100035888A1 (en) 2010-02-11
NO20082498L (no) 2008-08-07
SV2009002900A (es) 2009-04-28
IL191178A0 (en) 2009-08-03
JP2009514910A (ja) 2009-04-09
ECSP088430A (es) 2008-07-30
CA2628849A1 (en) 2007-05-18
BRPI0618522A2 (pt) 2011-09-06
TW200733961A (en) 2007-09-16
WO2007054216A1 (en) 2007-05-18
PE20070806A1 (es) 2007-09-29
EP1948170A1 (en) 2008-07-30

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT

Free format text: FORMER APPLICANT(S): BAYER HEALTHCARE AG

MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application