AU2006278227B2 - Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules - Google Patents

Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules Download PDF

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Publication number
AU2006278227B2
AU2006278227B2 AU2006278227A AU2006278227A AU2006278227B2 AU 2006278227 B2 AU2006278227 B2 AU 2006278227B2 AU 2006278227 A AU2006278227 A AU 2006278227A AU 2006278227 A AU2006278227 A AU 2006278227A AU 2006278227 B2 AU2006278227 B2 AU 2006278227B2
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AU
Australia
Prior art keywords
taci
dose
patient
treatment
patients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006278227A
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English (en)
Other versions
AU2006278227A8 (en
AU2006278227A1 (en
Inventor
Herve Broly
Eric Sievers
Arnaud Ythier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ares Trading SA
Zymogenetics Inc
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Ares Trading SA
Zymogenetics Inc
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Application filed by Ares Trading SA, Zymogenetics Inc filed Critical Ares Trading SA
Publication of AU2006278227A1 publication Critical patent/AU2006278227A1/en
Publication of AU2006278227A8 publication Critical patent/AU2006278227A8/en
Application granted granted Critical
Publication of AU2006278227B2 publication Critical patent/AU2006278227B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2006278227A 2005-08-09 2006-08-09 Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules Ceased AU2006278227B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70688805P 2005-08-09 2005-08-09
US60/706,888 2005-08-09
PCT/US2006/031274 WO2007019573A2 (en) 2005-08-09 2006-08-09 Methods for the treatment and prevention of abnormal cell proliferation using taci-fusion molecules

Publications (3)

Publication Number Publication Date
AU2006278227A1 AU2006278227A1 (en) 2007-02-15
AU2006278227A8 AU2006278227A8 (en) 2008-02-28
AU2006278227B2 true AU2006278227B2 (en) 2011-10-20

Family

ID=37670706

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006278227A Ceased AU2006278227B2 (en) 2005-08-09 2006-08-09 Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules

Country Status (9)

Country Link
US (1) US8808696B2 (enExample)
EP (1) EP1922079A2 (enExample)
JP (1) JP5118037B2 (enExample)
AR (1) AR059025A1 (enExample)
AU (1) AU2006278227B2 (enExample)
CA (1) CA2618763A1 (enExample)
IL (1) IL188404A (enExample)
NO (1) NO20081152L (enExample)
WO (1) WO2007019573A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7833529B1 (en) 1999-01-07 2010-11-16 Zymogenetics, Inc. Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
CN101262876A (zh) 2005-08-09 2008-09-10 酶遗传学股份有限公司 用taci-ig融合分子治疗b细胞恶性肿瘤的方法
WO2007019573A2 (en) 2005-08-09 2007-02-15 Zymogenetics, Inc. Methods for the treatment and prevention of abnormal cell proliferation using taci-fusion molecules
CN101489573B (zh) 2006-05-15 2013-05-22 阿雷斯贸易股份有限公司 用TACI-Ig融合分子治疗自身免疫疾病的方法
CN101323643B (zh) * 2007-06-15 2010-12-01 烟台荣昌生物工程有限公司 优化的TACI-Fc融合蛋白
US20170247462A1 (en) 2014-07-03 2017-08-31 Oklahoma Medical Research Foundation Treatment of multiple sclerosis and neuromyelitis optica
WO2019074983A1 (en) 2017-10-10 2019-04-18 Alpine Immune Sciences, Inc. CTLA-4 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF
WO2021226551A1 (en) 2020-05-08 2021-11-11 Alpine Immune Sciences, Inc. April and baff inhibitory immunomodulatory proteins and methods of use thereof
CN116897159A (zh) * 2021-03-31 2023-10-17 江苏恒瑞医药股份有限公司 截短的taci多肽及其融合蛋白和用途

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Also Published As

Publication number Publication date
JP2009504668A (ja) 2009-02-05
US8808696B2 (en) 2014-08-19
NO20081152L (no) 2008-03-04
JP5118037B2 (ja) 2013-01-16
AU2006278227A8 (en) 2008-02-28
US20070207156A1 (en) 2007-09-06
WO2007019573A3 (en) 2007-08-16
IL188404A (en) 2011-10-31
AR059025A1 (es) 2008-03-12
EP1922079A2 (en) 2008-05-21
AU2006278227A1 (en) 2007-02-15
IL188404A0 (en) 2008-08-07
CA2618763A1 (en) 2007-02-15
WO2007019573A2 (en) 2007-02-15

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Free format text: IN VOL 22, NO 6, PAGE(S) 633 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE -NAME INDEX UNDER THE NAME ARES TRADING S.A. AND ZYMOGENETICS, INC., APPLICATION NO. 2006278227, UNDER INID (54), CORRECT THE TITLE TO METHODS FOR THE TREATMENT AND PREVENTION OF ABNORMAL CELL PROLIFERATION USING TACI-FUSION MOLECULES.

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired