AU2005281483B2 - Drug delivery from embolic agents - Google Patents

Drug delivery from embolic agents Download PDF

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Publication number
AU2005281483B2
AU2005281483B2 AU2005281483A AU2005281483A AU2005281483B2 AU 2005281483 B2 AU2005281483 B2 AU 2005281483B2 AU 2005281483 A AU2005281483 A AU 2005281483A AU 2005281483 A AU2005281483 A AU 2005281483A AU 2005281483 B2 AU2005281483 B2 AU 2005281483B2
Authority
AU
Australia
Prior art keywords
group
microspheres
composition according
water
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005281483A
Other languages
English (en)
Other versions
AU2005281483A1 (en
Inventor
Maria Victoria Gonzalez-Fajardo
Andrew Lennard Lewis
Peter William Stratford
Yiqing Tang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocompatibles UK Ltd
Original Assignee
Biocompatibles UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocompatibles UK Ltd filed Critical Biocompatibles UK Ltd
Publication of AU2005281483A1 publication Critical patent/AU2005281483A1/en
Application granted granted Critical
Publication of AU2005281483B2 publication Critical patent/AU2005281483B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622—Microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
AU2005281483A 2004-09-07 2005-09-06 Drug delivery from embolic agents Ceased AU2005281483B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04255411.3 2004-09-07
EP04255411 2004-09-07
PCT/GB2005/003431 WO2006027567A2 (fr) 2004-09-07 2005-09-06 Administration de medicaments a partir d'agents d'embolisation

Publications (2)

Publication Number Publication Date
AU2005281483A1 AU2005281483A1 (en) 2006-03-16
AU2005281483B2 true AU2005281483B2 (en) 2008-11-27

Family

ID=34930630

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005281483A Ceased AU2005281483B2 (en) 2004-09-07 2005-09-06 Drug delivery from embolic agents

Country Status (11)

Country Link
US (3) US20070275991A1 (fr)
EP (3) EP3085361A1 (fr)
JP (4) JP5221134B2 (fr)
CN (2) CN101052378A (fr)
AT (1) ATE505185T1 (fr)
AU (1) AU2005281483B2 (fr)
CA (1) CA2579533C (fr)
DE (1) DE602005027477D1 (fr)
ES (1) ES2361919T3 (fr)
HK (1) HK1198691A1 (fr)
WO (1) WO2006027567A2 (fr)

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DE60130743T2 (de) 2000-03-24 2008-07-17 Biosphere Medical, Inc., Rockland Mikrokugeln zur aktiven embolisierung
WO2006013376A2 (fr) * 2004-08-04 2006-02-09 Biocompatibles Uk Limited Liberation de medicaments a partir d'agents emboliques
ES2568782T3 (es) 2005-05-09 2016-05-04 Biosphere Medical, S.A. Composiciones y métodos de uso de microesferas y agentes de contraste no iónicos
US9107833B2 (en) 2006-06-22 2015-08-18 Biocompatibles Uk Limited Rehydratable pharmaceutical product
EP1985286A1 (fr) * 2007-04-24 2008-10-29 Biocompatibles UK Limited Microsphères pour le traitement de tumeurs cérébrales
US20110229572A1 (en) * 2007-08-16 2011-09-22 Biocompatibles Uk Limited Delivery of drug combinations
EP3181123A1 (fr) 2008-12-02 2017-06-21 Biocompatibles Uk Ltd. Traitement de tumeur pancréatique
WO2012073188A1 (fr) * 2010-11-29 2012-06-07 Centre Hospitalier Universitaire Vaudois Composition de chimio-embolisation comprenant des agents anti-angiogéniques
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
CN102336904B (zh) * 2011-09-29 2013-03-27 成都一平医药科技发展有限公司 一种喜树碱及其衍生物的多价peg修饰物及其用途
CN102397593B (zh) * 2011-11-11 2013-12-18 北京大学 X线下可显影的栓塞微粒及其制备方法和应用
US20150352050A1 (en) * 2012-11-15 2015-12-10 Utah-Inha Dds & Advanced Therapeutics Research Center Biodegradable microbeads with improved anticancer drug adsorptivity, containing albumin and dextran sulfate, and preparation method therefor
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
WO2014084530A1 (fr) 2012-11-27 2014-06-05 재단법인 유타 인하 디디에스 및 신의료기술개발공동연구소 Microbille biodégradable comprenant un polymère anionique pour améliorer la capacité d'adsorption de médicaments anticancéreux, et procédé de préparation de celle-ci
BR112016005770B1 (pt) 2013-09-19 2021-07-27 Terumo Corporation Partículas de polímero
AU2014321278B2 (en) 2013-09-19 2016-11-10 Microvention, Inc. Polymer films
KR102287781B1 (ko) 2013-11-08 2021-08-06 테루모 가부시키가이샤 중합체 입자
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
JP2016124818A (ja) * 2014-12-26 2016-07-11 日本化薬株式会社 転移性肝癌治療薬及び転移性肝癌の治療方法
WO2016154592A1 (fr) 2015-03-26 2016-09-29 Microvention, Inc. Particules emboliques
WO2016203337A2 (fr) * 2015-06-14 2016-12-22 Mohan M Alapati Compositions et méthodes de traitement du cancer
WO2016203352A2 (fr) * 2015-06-14 2016-12-22 Mohan M Alapati Compositions et méthodes de traitement du cancer
GB201515602D0 (en) 2015-09-03 2015-10-21 Biocompatibles Uk Ltd Polymers and microspheres
US10328175B2 (en) 2016-09-28 2019-06-25 Terumo Corporation Polymer particles
WO2018218208A1 (fr) 2017-05-26 2018-11-29 Bruin Biosciences, Inc. Agents pour chimio-embolisation
CN107812232A (zh) * 2017-11-08 2018-03-20 华威（深圳）医疗器械有限责任公司 可显影羧基改性聚乙烯醇微球栓塞剂及其制备工艺
CN113164650B (zh) * 2018-11-30 2023-04-04 株式会社 Nextbiomedical 包含生物降解高分子的用于化疗栓塞的水凝胶粒子
JP7275694B2 (ja) 2019-03-18 2023-05-18 株式会社リコー 感熱記録媒体、及び物品
GB201918300D0 (en) * 2019-12-12 2020-01-29 Extruded Pharmaceuticals Ltd Chemotherapeutic drug implant

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Also Published As

Publication number Publication date
US20120201867A1 (en) 2012-08-09
ATE505185T1 (de) 2011-04-15
EP1796644B1 (fr) 2011-04-13
WO2006027567A2 (fr) 2006-03-16
JP5221134B2 (ja) 2013-06-26
CN101052378A (zh) 2007-10-10
EP2269580A3 (fr) 2011-11-09
JP2017025071A (ja) 2017-02-02
JP2008512370A (ja) 2008-04-24
DE602005027477D1 (de) 2011-05-26
CA2579533A1 (fr) 2006-03-16
CA2579533C (fr) 2013-05-21
AU2005281483A1 (en) 2006-03-16
US20120276151A1 (en) 2012-11-01
HK1198691A1 (en) 2015-05-29
EP1796644A2 (fr) 2007-06-20
US20070275991A1 (en) 2007-11-29
EP3085361A1 (fr) 2016-10-26
JP2015180625A (ja) 2015-10-15
WO2006027567A3 (fr) 2006-05-18
CN103860479A (zh) 2014-06-18
JP2012236840A (ja) 2012-12-06
EP2269580A2 (fr) 2011-01-05
JP5792691B2 (ja) 2015-10-14
ES2361919T3 (es) 2011-06-24

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired