AU2005235786A1 - Benzoxazocines and their therapeutic use as monoamine reuptake inhibitors - Google Patents

Benzoxazocines and their therapeutic use as monoamine reuptake inhibitors Download PDF

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Publication number
AU2005235786A1
AU2005235786A1 AU2005235786A AU2005235786A AU2005235786A1 AU 2005235786 A1 AU2005235786 A1 AU 2005235786A1 AU 2005235786 A AU2005235786 A AU 2005235786A AU 2005235786 A AU2005235786 A AU 2005235786A AU 2005235786 A1 AU2005235786 A1 AU 2005235786A1
Authority
AU
Australia
Prior art keywords
methyl
tetrahydro
oxazocine
phenyl
benz
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2005235786A
Other languages
English (en)
Inventor
Andrew Douglas Baxter
Elena Lasterra
Andrea Walmsley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sosei R&D Ltd
Original Assignee
Sosei R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0408863A external-priority patent/GB0408863D0/en
Priority claimed from GB0408862A external-priority patent/GB0408862D0/en
Application filed by Sosei R&D Ltd filed Critical Sosei R&D Ltd
Publication of AU2005235786A1 publication Critical patent/AU2005235786A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Addiction (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2005235786A 2004-04-21 2005-04-21 Benzoxazocines and their therapeutic use as monoamine reuptake inhibitors Abandoned AU2005235786A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0408863A GB0408863D0 (en) 2004-04-21 2004-04-21 Novel benzoxazocines
GB0408862.1 2004-04-21
GB0408863.9 2004-04-21
GB0408862A GB0408862D0 (en) 2004-04-21 2004-04-21 Novel benzoxazocines
PCT/GB2005/001519 WO2005103019A1 (en) 2004-04-21 2005-04-21 Benzoxazocines and their therapeutic use as monoamine reuptake inhibitors

Publications (1)

Publication Number Publication Date
AU2005235786A1 true AU2005235786A1 (en) 2005-11-03

Family

ID=34965745

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005235786A Abandoned AU2005235786A1 (en) 2004-04-21 2005-04-21 Benzoxazocines and their therapeutic use as monoamine reuptake inhibitors

Country Status (8)

Country Link
EP (1) EP1740558A1 (no)
JP (1) JP2007533718A (no)
AU (1) AU2005235786A1 (no)
BR (1) BRPI0510075A (no)
CA (1) CA2558741A1 (no)
IL (1) IL177750A0 (no)
NO (1) NO20065057L (no)
WO (1) WO2005103019A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0504960D0 (en) * 2005-03-10 2005-04-20 Arakis Ltd Benzoxazocines
GB0506835D0 (en) * 2005-04-04 2005-05-11 Arakis Ltd Therapeutic use of nefopam
CN102781442B (zh) 2009-12-15 2016-02-17 儿童医院 使用奈福泮化合物治疗瘢痕和β-联蛋白介导的疾病的方法
WO2012007500A2 (de) 2010-07-15 2012-01-19 Bayer Cropscience Ag Neue heterocyclische verbindungen als schädlingsbekämpfungsmittel

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3830803A (en) * 1965-05-10 1974-08-20 Riker Laboratories Inc 5-loweralkyl-1-phenyl-1,3,4,6-tetrahydro-5h-benz(f)-2,5-oxazocines and 4-ones
US3978085A (en) * 1975-03-07 1976-08-31 Riker Laboratories, Inc. Process for benz[f]-2,5-oxazocines
JPS5913760A (ja) * 1982-07-13 1984-01-24 Sanwa Kagaku Kenkyusho:Kk 新規の２−ベンズアゾシン誘導体及びその製法
JPS5913770A (ja) * 1982-07-13 1984-01-24 Sanwa Kagaku Kenkyusho:Kk 新規の１−フエニル−２，５−ベンゾチアゾシン誘導体及びその製法
DK1246806T3 (da) * 1999-11-03 2008-06-16 Amr Technology Inc Aryl- og heteroarylsubstituerede tetrahydroisoquinoliner og anvendelse deraf til blokering af genoptagelse af norepinefrin, dopsmin og serotonin
AU2003295171B2 (en) * 2002-12-20 2007-09-06 Arakis Ltd. Benzoxazocines and their use as monoamine-reuptake inhibitors

Also Published As

Publication number Publication date
JP2007533718A (ja) 2007-11-22
BRPI0510075A (pt) 2007-10-16
CA2558741A1 (en) 2005-11-03
IL177750A0 (en) 2006-12-31
NO20065057L (no) 2006-11-21
WO2005103019A1 (en) 2005-11-03
EP1740558A1 (en) 2007-01-10

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted