BRPI0510075A - benzoxazocinas e seu uso terapêutico como inibidores de reabsorção de monoamina - Google Patents

benzoxazocinas e seu uso terapêutico como inibidores de reabsorção de monoamina

Info

Publication number
BRPI0510075A
BRPI0510075A BRPI0510075-5A BRPI0510075A BRPI0510075A BR PI0510075 A BRPI0510075 A BR PI0510075A BR PI0510075 A BRPI0510075 A BR PI0510075A BR PI0510075 A BRPI0510075 A BR PI0510075A
Authority
BR
Brazil
Prior art keywords
optionally substituted
alkyl
unsubstituted
cycloalkyl
alkenyl
Prior art date
Application number
BRPI0510075-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Andrew Douglas Baxter
Andrea Walmsley
Elena Lasterra
Original Assignee
Sosei R & D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0408862A external-priority patent/GB0408862D0/en
Priority claimed from GB0408863A external-priority patent/GB0408863D0/en
Application filed by Sosei R & D Ltd filed Critical Sosei R & D Ltd
Publication of BRPI0510075A publication Critical patent/BRPI0510075A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0510075-5A 2004-04-21 2005-04-21 benzoxazocinas e seu uso terapêutico como inibidores de reabsorção de monoamina BRPI0510075A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0408862A GB0408862D0 (en) 2004-04-21 2004-04-21 Novel benzoxazocines
GB0408863A GB0408863D0 (en) 2004-04-21 2004-04-21 Novel benzoxazocines
PCT/GB2005/001519 WO2005103019A1 (en) 2004-04-21 2005-04-21 Benzoxazocines and their therapeutic use as monoamine reuptake inhibitors

Publications (1)

Publication Number Publication Date
BRPI0510075A true BRPI0510075A (pt) 2007-10-16

Family

ID=34965745

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510075-5A BRPI0510075A (pt) 2004-04-21 2005-04-21 benzoxazocinas e seu uso terapêutico como inibidores de reabsorção de monoamina

Country Status (8)

Country Link
EP (1) EP1740558A1 (no)
JP (1) JP2007533718A (no)
AU (1) AU2005235786A1 (no)
BR (1) BRPI0510075A (no)
CA (1) CA2558741A1 (no)
IL (1) IL177750A0 (no)
NO (1) NO20065057L (no)
WO (1) WO2005103019A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0504960D0 (en) * 2005-03-10 2005-04-20 Arakis Ltd Benzoxazocines
GB0506835D0 (en) * 2005-04-04 2005-05-11 Arakis Ltd Therapeutic use of nefopam
BR112012014471A2 (pt) 2009-12-15 2017-06-06 Hospital For Sick Children método para o tratamento de cicatrizes e de distúrbios mediados por beta-catenina usando compostos nefopam
WO2012007500A2 (de) 2010-07-15 2012-01-19 Bayer Cropscience Ag Neue heterocyclische verbindungen als schädlingsbekämpfungsmittel

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3830803A (en) * 1965-05-10 1974-08-20 Riker Laboratories Inc 5-loweralkyl-1-phenyl-1,3,4,6-tetrahydro-5h-benz(f)-2,5-oxazocines and 4-ones
US3978085A (en) * 1975-03-07 1976-08-31 Riker Laboratories, Inc. Process for benz[f]-2,5-oxazocines
JPS5913760A (ja) * 1982-07-13 1984-01-24 Sanwa Kagaku Kenkyusho:Kk 新規の２−ベンズアゾシン誘導体及びその製法
JPS5913770A (ja) * 1982-07-13 1984-01-24 Sanwa Kagaku Kenkyusho:Kk 新規の１−フエニル−２，５−ベンゾチアゾシン誘導体及びその製法
DE60038185T2 (de) * 1999-11-03 2009-02-19 Amr Technology, Inc. Arly- und heteroaryl-substituierte tetrahydroisoquinoline und ihre verwendung als hemmer der wiederaufnahme von norepinephrin, dopamin und serotonin
WO2004056788A1 (en) * 2002-12-20 2004-07-08 Arakis Ltd. Benzoxazocines and their use as monoamine-reuptake inhibitors

Also Published As

Publication number Publication date
NO20065057L (no) 2006-11-21
CA2558741A1 (en) 2005-11-03
EP1740558A1 (en) 2007-01-10
AU2005235786A1 (en) 2005-11-03
JP2007533718A (ja) 2007-11-22
WO2005103019A1 (en) 2005-11-03
IL177750A0 (en) 2006-12-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.