AU2004234320A1 - Use of derivatives of 2, 4-dihydro-(1,2,4)triazole-3-thione as inhibitors o fteh enzyme myeloperoxidase (MPO) - Google Patents

Use of derivatives of 2, 4-dihydro-(1,2,4)triazole-3-thione as inhibitors o fteh enzyme myeloperoxidase (MPO) Download PDF

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Publication number
AU2004234320A1
AU2004234320A1 AU2004234320A AU2004234320A AU2004234320A1 AU 2004234320 A1 AU2004234320 A1 AU 2004234320A1 AU 2004234320 A AU2004234320 A AU 2004234320A AU 2004234320 A AU2004234320 A AU 2004234320A AU 2004234320 A1 AU2004234320 A1 AU 2004234320A1
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Prior art keywords
thione
triazole
dihydro
phenyl
chlorobenzyl
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AU2004234320A
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Mats Svensson
Anna-Karin Tiden
Dominika Turek
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AstraZeneca AB
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AstraZeneca AB
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
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    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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AU2004234320A 2003-04-25 2004-04-22 Use of derivatives of 2, 4-dihydro-(1,2,4)triazole-3-thione as inhibitors o fteh enzyme myeloperoxidase (MPO) Abandoned AU2004234320A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0301232-5 2003-04-25
SE0301232A SE0301232D0 (sv) 2003-04-25 2003-04-25 Novel use
PCT/SE2004/000618 WO2004096781A1 (en) 2003-04-25 2004-04-22 Use of derivatives of 2, 4-dihydro-[1,2,4]triazole-3-thione as inhibitors o fteh enzyme myeloperoxidase (mpo)

Publications (1)

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AU2004234320A1 true AU2004234320A1 (en) 2004-11-11

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AU2004234320A Abandoned AU2004234320A1 (en) 2003-04-25 2004-04-22 Use of derivatives of 2, 4-dihydro-(1,2,4)triazole-3-thione as inhibitors o fteh enzyme myeloperoxidase (MPO)

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Country Link
US (1) US20070093483A1 (enExample)
EP (1) EP1620410A1 (enExample)
JP (1) JP2006524686A (enExample)
KR (1) KR20060006064A (enExample)
CN (1) CN1780822A (enExample)
AU (1) AU2004234320A1 (enExample)
BR (1) BRPI0409498A (enExample)
CA (1) CA2523020A1 (enExample)
MX (1) MXPA05011207A (enExample)
NO (1) NO20055565L (enExample)
SE (1) SE0301232D0 (enExample)
WO (1) WO2004096781A1 (enExample)
ZA (1) ZA200508623B (enExample)

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CN101723909B (zh) * 2008-10-29 2011-12-28 天津药物研究院 三唑酮类化合物、其制备方法和用途
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WO2011133581A1 (en) 2010-04-19 2011-10-27 General Atomics Methods and compositions for assaying enzymatic activity of myeloperoxidase in blood samples
WO2013067162A1 (en) 2011-11-02 2013-05-10 Synta Pharmaceuticals Corp. Cancer therapy using a combination of hsp90 inhibitors with topoisomerase i inhibitors
AU2012332424A1 (en) 2011-11-02 2014-06-05 Synta Pharmaceuticals Corp. Combination therapy of Hsp90 inhibitors with platinum-containing agents
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BR112020008727A2 (pt) 2017-10-30 2020-10-20 Neuropore Therapies, Inc. fenil sulfonil fenil triazol tionas substituídas e usos destas
KR20200083843A (ko) 2018-12-31 2020-07-09 공주대학교 산학협력단 4-(2-플루오로페닐)-3-(3-메톡시벤질)-1h-1,2,4-트리아졸-5(4h)-온 및 이의 퇴행성 뇌질환 및 대사성 질환 치료제로서의 용도
CN110313401A (zh) * 2019-07-12 2019-10-11 华南农业大学 一种促进企剑白墨墨兰组织培养过程中芽分化的方法
CA3181917A1 (en) * 2020-05-06 2021-11-11 Biohaven Therapeutics Ltd. Process for the preparation of verdiperstat
PL248780B1 (pl) * 2023-05-15 2026-01-26 Univ Medyczny Im Piastow Slaskich We Wroclawiu Nowe pochodne 4,6-dimetylo-2-sulfanylopirydyny sprzężone z pierścieniem 1,2,4-triazolu, sposób syntezy pochodnych oraz zastosowanie pochodnych
US11926602B1 (en) * 2023-08-23 2024-03-12 King Faisal University 4-amino-5-(4-fluoro-3-phenoxyphenyl)-4H-1,2,4-triazole-3-thiol derivatives as antifungal agents

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NO20055565D0 (no) 2005-11-24
BRPI0409498A (pt) 2006-05-02
CA2523020A1 (en) 2004-11-11
SE0301232D0 (sv) 2003-04-25
MXPA05011207A (es) 2005-12-14
KR20060006064A (ko) 2006-01-18
US20070093483A1 (en) 2007-04-26
NO20055565L (no) 2006-01-25
WO2004096781A1 (en) 2004-11-11
EP1620410A1 (en) 2006-02-01
ZA200508623B (en) 2007-07-25
JP2006524686A (ja) 2006-11-02

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