AU2003282337B2 - Neuroprotective iron chelators and pharmaceutical compositions comprising them - Google Patents

Neuroprotective iron chelators and pharmaceutical compositions comprising them Download PDF

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Publication number
AU2003282337B2
AU2003282337B2 AU2003282337A AU2003282337A AU2003282337B2 AU 2003282337 B2 AU2003282337 B2 AU 2003282337B2 AU 2003282337 A AU2003282337 A AU 2003282337A AU 2003282337 A AU2003282337 A AU 2003282337A AU 2003282337 B2 AU2003282337 B2 AU 2003282337B2
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AU2003282337A1 (en
Inventor
Matitiyahu Fridkin
Abraham Warshawsky
Rivka Warshawsky
Moussa B. H. Youdim
Hailin Zheng
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Technion Research and Development Foundation Ltd
Yeda Research and Development Co Ltd
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Technion Research and Development Foundation Ltd
Yeda Research and Development Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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AU2003282337A 2002-11-07 2003-11-07 Neuroprotective iron chelators and pharmaceutical compositions comprising them Ceased AU2003282337B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42431302P 2002-11-07 2002-11-07
US60/424,313 2002-11-07
US50412603P 2003-09-22 2003-09-22
US60/504,126 2003-09-22
PCT/IL2003/000932 WO2004041151A2 (en) 2002-11-07 2003-11-07 Neuroprotective iron chelators and pharmaceutical compositions comprising them

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AU2003282337A1 AU2003282337A1 (en) 2004-06-07
AU2003282337B2 true AU2003282337B2 (en) 2009-07-16

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US8058442B2 (en) 2011-11-15
CA2505476C (en) 2015-05-26
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WO2004041151A2 (en) 2004-05-21
WO2004041151A3 (en) 2004-10-28
EP1565185A2 (en) 2005-08-24
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US8685955B2 (en) 2014-04-01
IL168419A (en) 2017-01-31

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