FR2913976B1 - Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers. - Google Patents

Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.

Info

Publication number
FR2913976B1
FR2913976B1 FR0702154A FR0702154A FR2913976B1 FR 2913976 B1 FR2913976 B1 FR 2913976B1 FR 0702154 A FR0702154 A FR 0702154A FR 0702154 A FR0702154 A FR 0702154A FR 2913976 B1 FR2913976 B1 FR 2913976B1
Authority
FR
France
Prior art keywords
hydroxyquinoline
cancers
classes
amine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0702154A
Other languages
English (en)
Other versions
FR2913976A1 (fr
Inventor
Jean Louis Kraus
Olivier Blin
Frederic Champavere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biopharmed
Original Assignee
Biopharmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0702154A priority Critical patent/FR2913976B1/fr
Application filed by Biopharmed filed Critical Biopharmed
Priority to EP08787845A priority patent/EP2139860A2/fr
Priority to US12/532,695 priority patent/US8324243B2/en
Priority to CA002680803A priority patent/CA2680803A1/fr
Priority to CN200880007473.7A priority patent/CN101641332B/zh
Priority to PCT/FR2008/000399 priority patent/WO2008135671A2/fr
Priority to AU2008248475A priority patent/AU2008248475B2/en
Priority to JP2009554065A priority patent/JP5555494B2/ja
Publication of FR2913976A1 publication Critical patent/FR2913976A1/fr
Priority to US13/690,137 priority patent/US8614230B2/en
Application granted granted Critical
Publication of FR2913976B1 publication Critical patent/FR2913976B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0702154A 2007-03-23 2007-03-23 Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers. Expired - Fee Related FR2913976B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR0702154A FR2913976B1 (fr) 2007-03-23 2007-03-23 Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.
US12/532,695 US8324243B2 (en) 2007-03-23 2008-03-25 Derivatives of the aminated hydroxyquinoline class for treating cancers
CA002680803A CA2680803A1 (fr) 2007-03-23 2008-03-25 Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers
CN200880007473.7A CN101641332B (zh) 2007-03-23 2008-03-25 用于治疗癌症的胺化的羟基喹啉类衍生物
EP08787845A EP2139860A2 (fr) 2007-03-23 2008-03-25 Dérivés de la classe des hydroxyquinoléines aminées pour le traitement de cancers.
PCT/FR2008/000399 WO2008135671A2 (fr) 2007-03-23 2008-03-25 Dérivés de la classe des hydroxyquinoléines aminées pour le traitement de cancers.
AU2008248475A AU2008248475B2 (en) 2007-03-23 2008-03-25 Derivatives of the aminated hydroxyquinoline class for treating cancers
JP2009554065A JP5555494B2 (ja) 2007-03-23 2008-03-25 癌を治療するためのアミノ化ヒドロキシキノリン類誘導体
US13/690,137 US8614230B2 (en) 2007-03-23 2012-11-30 Derivatives of the aminated hydroxyquinoline class for treating cancers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0702154A FR2913976B1 (fr) 2007-03-23 2007-03-23 Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.

Publications (2)

Publication Number Publication Date
FR2913976A1 FR2913976A1 (fr) 2008-09-26
FR2913976B1 true FR2913976B1 (fr) 2013-04-26

Family

ID=38686734

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0702154A Expired - Fee Related FR2913976B1 (fr) 2007-03-23 2007-03-23 Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.

Country Status (8)

Country Link
US (2) US8324243B2 (fr)
EP (1) EP2139860A2 (fr)
JP (1) JP5555494B2 (fr)
CN (1) CN101641332B (fr)
AU (1) AU2008248475B2 (fr)
CA (1) CA2680803A1 (fr)
FR (1) FR2913976B1 (fr)
WO (1) WO2008135671A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2913976B1 (fr) * 2007-03-23 2013-04-26 Biopharmed Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.
EP2149567A1 (fr) * 2008-07-18 2010-02-03 Bayer Schering Pharma Aktiengesellschaft Composé pour la liaison de phosphatidylsérine
FR2940289B1 (fr) * 2008-12-23 2014-09-12 Biopharmed Derives de la classe des hydroxyquinoleines aminees pour le traitement du cancer du pancreas
KR101514285B1 (ko) 2013-08-09 2015-04-22 숙명여자대학교산학협력단 아미노다이하이드로퀴놀린 화합물 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 암 질환의 예방 또는 치료용 약학적 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5736192A (ja) * 1980-08-13 1982-02-26 Nippon Oil Co Ltd Kinzokufukatsuseikazaioyobisonososeibutsu
IL130324A0 (en) * 1999-06-07 2000-06-01 Yeda Res & Dev Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators
US8058442B2 (en) * 2002-11-07 2011-11-15 Technion Research And Development Foundation Ltd. Neuroprotective iron chelators and pharmaceutical compositions comprising them
CN1295218C (zh) * 2004-06-18 2007-01-17 中国科学院广州化学研究所 单官能团8－羟基喹啉金属配合物的烯类单体及其制法和用途
FR2913976B1 (fr) * 2007-03-23 2013-04-26 Biopharmed Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.

Also Published As

Publication number Publication date
WO2008135671A3 (fr) 2009-05-22
FR2913976A1 (fr) 2008-09-26
CN101641332B (zh) 2014-03-12
US20100120856A1 (en) 2010-05-13
AU2008248475B2 (en) 2013-10-03
US20130102630A1 (en) 2013-04-25
US8324243B2 (en) 2012-12-04
US8614230B2 (en) 2013-12-24
JP5555494B2 (ja) 2014-07-23
JP2010522147A (ja) 2010-07-01
CA2680803A1 (fr) 2008-11-13
CN101641332A (zh) 2010-02-03
EP2139860A2 (fr) 2010-01-06
AU2008248475A1 (en) 2008-11-13
WO2008135671A2 (fr) 2008-11-13

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Year of fee payment: 10

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Effective date: 20171130