AU2003273306B2 - Method and apparatus for epidermal delivery of a substance - Google Patents
Method and apparatus for epidermal delivery of a substance Download PDFInfo
- Publication number
- AU2003273306B2 AU2003273306B2 AU2003273306A AU2003273306A AU2003273306B2 AU 2003273306 B2 AU2003273306 B2 AU 2003273306B2 AU 2003273306 A AU2003273306 A AU 2003273306A AU 2003273306 A AU2003273306 A AU 2003273306A AU 2003273306 B2 AU2003273306 B2 AU 2003273306B2
- Authority
- AU
- Australia
- Prior art keywords
- skin
- substance
- needle
- side port
- port
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000000126 substance Substances 0.000 title claims abstract description 116
- 238000000034 method Methods 0.000 title claims abstract description 34
- 210000003491 skin Anatomy 0.000 claims description 139
- 239000003814 drug Substances 0.000 claims description 31
- 210000004207 dermis Anatomy 0.000 claims description 30
- 229940079593 drug Drugs 0.000 claims description 29
- 210000002615 epidermis Anatomy 0.000 claims description 28
- 230000035515 penetration Effects 0.000 claims description 25
- 238000001802 infusion Methods 0.000 claims description 17
- 238000007920 subcutaneous administration Methods 0.000 claims description 17
- 229960005486 vaccine Drugs 0.000 claims description 17
- 238000010521 absorption reaction Methods 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 9
- 238000004891 communication Methods 0.000 claims description 8
- 239000000427 antigen Substances 0.000 claims description 5
- 102000036639 antigens Human genes 0.000 claims description 5
- 108091007433 antigens Proteins 0.000 claims description 5
- 150000004676 glycans Chemical class 0.000 claims description 4
- 229920000642 polymer Polymers 0.000 claims description 4
- 229920001282 polysaccharide Polymers 0.000 claims description 4
- 239000005017 polysaccharide Substances 0.000 claims description 4
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 230000037368 penetrate the skin Effects 0.000 abstract description 4
- 239000012530 fluid Substances 0.000 description 21
- 238000002347 injection Methods 0.000 description 16
- 239000007924 injection Substances 0.000 description 16
- 210000001519 tissue Anatomy 0.000 description 9
- 238000012360 testing method Methods 0.000 description 8
- 206010033675 panniculitis Diseases 0.000 description 7
- 210000004304 subcutaneous tissue Anatomy 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000013459 approach Methods 0.000 description 5
- 230000008901 benefit Effects 0.000 description 5
- 238000012377 drug delivery Methods 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000007918 intramuscular administration Methods 0.000 description 3
- 210000000434 stratum corneum Anatomy 0.000 description 3
- 230000037317 transdermal delivery Effects 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 229960000484 ceftazidime Drugs 0.000 description 2
- NMVPEQXCMGEDNH-TZVUEUGBSA-N ceftazidime pentahydrate Chemical compound O.O.O.O.O.S([C@@H]1[C@@H](C(N1C=1C([O-])=O)=O)NC(=O)\C(=N/OC(C)(C)C(O)=O)C=2N=C(N)SC=2)CC=1C[N+]1=CC=CC=C1 NMVPEQXCMGEDNH-TZVUEUGBSA-N 0.000 description 2
- 210000002808 connective tissue Anatomy 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 238000010255 intramuscular injection Methods 0.000 description 2
- 239000007927 intramuscular injection Substances 0.000 description 2
- 150000002605 large molecules Chemical class 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 239000004005 microsphere Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 238000007910 systemic administration Methods 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- 102000055006 Calcitonin Human genes 0.000 description 1
- 108060001064 Calcitonin Proteins 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 210000000612 antigen-presenting cell Anatomy 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 description 1
- 229960004015 calcitonin Drugs 0.000 description 1
- 238000005056 compaction Methods 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000012938 design process Methods 0.000 description 1
- 229940039227 diagnostic agent Drugs 0.000 description 1
- 239000000032 diagnostic agent Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000013583 drug formulation Substances 0.000 description 1
- 238000004520 electroporation Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229940127560 insulin pen Drugs 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000036470 plasma concentration Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 230000037204 skin physiology Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229960001005 tuberculin Drugs 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
- A61M5/3291—Shafts with additional lateral openings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14208—Pressure infusion, e.g. using pumps with a programmable infusion control system, characterised by the infusion program
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1581—Right-angle needle-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40919302P | 2002-09-10 | 2002-09-10 | |
| US60/409,193 | 2002-09-10 | ||
| PCT/US2003/028273 WO2004024219A1 (en) | 2002-09-10 | 2003-09-10 | Method and apparatus for epidermal delivery of a substance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003273306A1 AU2003273306A1 (en) | 2004-04-30 |
| AU2003273306B2 true AU2003273306B2 (en) | 2009-04-30 |
Family
ID=31993949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003273306A Ceased AU2003273306B2 (en) | 2002-09-10 | 2003-09-10 | Method and apparatus for epidermal delivery of a substance |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040092893A1 (enExample) |
| EP (1) | EP1539281B1 (enExample) |
| JP (1) | JP2005537893A (enExample) |
| AT (1) | ATE363310T1 (enExample) |
| AU (1) | AU2003273306B2 (enExample) |
| CA (1) | CA2498027C (enExample) |
| DE (1) | DE60314157T2 (enExample) |
| DK (1) | DK1539281T3 (enExample) |
| ES (1) | ES2287517T3 (enExample) |
| WO (1) | WO2004024219A1 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1301228B1 (en) * | 2000-07-13 | 2008-07-23 | Abbott Cardiovascular Systems Inc. | Deployment system for myocardial cellular material |
| US8574195B2 (en) * | 2002-06-10 | 2013-11-05 | Advanced Cardiovascular Systems, Inc. | Systems and methods for detecting tissue contact and needle penetration depth using static fluid pressure measurements |
| US7364567B2 (en) | 2002-06-10 | 2008-04-29 | Abbott Cardiovascular Systems Inc. | Systems and methods for detecting tissue contact and needle penetration depth |
| CA2820537C (en) | 2003-04-23 | 2015-10-20 | Valeritas, Inc. | Hydraulically actuated pump for fluid administration |
| US8308708B2 (en) * | 2003-07-15 | 2012-11-13 | Abbott Cardiovascular Systems Inc. | Deployment system for myocardial cellular material |
| US7787923B2 (en) * | 2003-11-26 | 2010-08-31 | Becton, Dickinson And Company | Fiber optic device for sensing analytes and method of making same |
| US9089636B2 (en) | 2004-07-02 | 2015-07-28 | Valeritas, Inc. | Methods and devices for delivering GLP-1 and uses thereof |
| ATE480278T1 (de) | 2005-09-12 | 2010-09-15 | Unomedical As | Einfürungssystem für ein infusionsset mit einem ersten und zweiten federeinheit |
| US9211379B2 (en) | 2006-02-28 | 2015-12-15 | Unomedical A/S | Inserter for infusion part and infusion part provided with needle protector |
| ES2656675T3 (es) | 2006-03-30 | 2018-02-28 | Valeritas, Inc. | Dispositivo de suministro de fluidos de múltiples cartuchos |
| MX2008015247A (es) | 2006-06-09 | 2008-12-15 | Unomedical As | Almohadilla de montaje. |
| EP2046419B1 (en) | 2006-08-02 | 2011-04-13 | Unomedical A/S | Cannula and delivery device |
| US20090326415A1 (en) * | 2006-08-28 | 2009-12-31 | Agency For Science ,Technology And Research | Microneedles and methods for fabricating microneedles |
| EP2063934A1 (en) * | 2006-09-18 | 2009-06-03 | Agency for Science, Technology and Research | Needle structures and methods for fabricating needle structures |
| KR20100123711A (ko) | 2008-02-13 | 2010-11-24 | 우노메디컬 에이/에스 | 캐뉼라부와 유체 통로 사이의 밀봉부 |
| EP2259816B1 (en) | 2008-02-20 | 2015-10-21 | Unomedical A/S | Insertion device with horizontally moving part |
| CA2747307A1 (en) | 2008-12-22 | 2010-07-01 | Unomedical A/S | Medical device comprising adhesive pad |
| EP3384942B1 (en) | 2009-01-12 | 2025-09-17 | Becton, Dickinson and Company | Infusion set and/or patch pump having at least one of an in-dwelling rigid catheter with flexible features and/or a flexible catheter attachment |
| AU2010231527A1 (en) * | 2009-03-30 | 2011-11-03 | F.Hoffmann-La Roche Ag | Devices and methods for enhancing drug absorption rate |
| AU2010277755A1 (en) | 2009-07-30 | 2012-02-02 | Unomedical A/S | Inserter device with horizontal moving part |
| KR20120047896A (ko) | 2009-08-07 | 2012-05-14 | 우노메디컬 에이/에스 | 센서와 하나 또는 그 이상의 캐뉼라들을 가진 전달 장치 |
| US9199034B2 (en) * | 2009-11-09 | 2015-12-01 | Becton, Dickinson And Company | Drug delivery devices, systems, and methods |
| US8449504B2 (en) * | 2009-11-11 | 2013-05-28 | Calibra Medical, Inc. | Wearable infusion device and system |
| JP2013523233A (ja) | 2010-03-30 | 2013-06-17 | ウノメディカル アクティーゼルスカブ | 医療デバイス |
| EP2433663A1 (en) | 2010-09-27 | 2012-03-28 | Unomedical A/S | Insertion system |
| EP2436412A1 (en) * | 2010-10-04 | 2012-04-04 | Unomedical A/S | A sprinkler cannula |
| US20120209245A1 (en) * | 2011-02-16 | 2012-08-16 | Greg Yukio Uramoto | Process for using a needle having multiple apertures for injections into subcutaneous tissue |
| WO2013050277A1 (en) | 2011-10-05 | 2013-04-11 | Unomedical A/S | Inserter for simultaneous insertion of multiple transcutaneous parts |
| EP2583715A1 (en) | 2011-10-19 | 2013-04-24 | Unomedical A/S | Infusion tube system and method for manufacture |
| US9440051B2 (en) | 2011-10-27 | 2016-09-13 | Unomedical A/S | Inserter for a multiplicity of subcutaneous parts |
| JP5767568B2 (ja) * | 2011-11-16 | 2015-08-19 | ニプロ株式会社 | ワクチン接種針 |
| CA3043581C (en) | 2011-12-07 | 2022-05-24 | Ralph Sonderegger | Infusion device with releasable fluid connector |
| EP2902064B1 (en) | 2011-12-07 | 2018-07-04 | Becton, Dickinson and Company | Needle shielding assemblies and infusion devices for use therewith |
| WO2013103864A1 (en) * | 2012-01-05 | 2013-07-11 | Becton, Dickinson And Company | Split and side-ported catheter devices |
| WO2014028285A1 (en) * | 2012-08-13 | 2014-02-20 | The Brigham And Women's Hospital, Inc. | Methods and devices for inserting a needle |
| EP3072548B1 (en) | 2012-11-21 | 2019-03-06 | Amgen, Inc | Drug delivery device |
| WO2014200924A1 (en) | 2013-06-10 | 2014-12-18 | Facet Technologies, Llc | Lancet needle with alignment and retention notch |
| JPWO2015107774A1 (ja) | 2014-01-16 | 2017-03-23 | テルモ株式会社 | 皮膚上層部への薬液注入用注射器 |
| WO2016178914A1 (en) * | 2015-05-01 | 2016-11-10 | Cesca Therapeutics, Inc. | Intramuscular adaminstration of autologous bone marrw for treatment |
| WO2017010564A1 (ja) | 2015-07-15 | 2017-01-19 | テルモ株式会社 | 免疫療法用の皮内注射針 |
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2003
- 2003-09-10 AU AU2003273306A patent/AU2003273306B2/en not_active Ceased
- 2003-09-10 EP EP03755805A patent/EP1539281B1/en not_active Expired - Lifetime
- 2003-09-10 US US10/659,245 patent/US20040092893A1/en not_active Abandoned
- 2003-09-10 JP JP2004536400A patent/JP2005537893A/ja active Pending
- 2003-09-10 AT AT03755805T patent/ATE363310T1/de not_active IP Right Cessation
- 2003-09-10 DK DK03755805T patent/DK1539281T3/da active
- 2003-09-10 CA CA2498027A patent/CA2498027C/en not_active Expired - Fee Related
- 2003-09-10 DE DE60314157T patent/DE60314157T2/de not_active Expired - Lifetime
- 2003-09-10 ES ES03755805T patent/ES2287517T3/es not_active Expired - Lifetime
- 2003-09-10 WO PCT/US2003/028273 patent/WO2004024219A1/en not_active Ceased
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2005
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| DE19512607A1 (de) * | 1995-04-04 | 1996-10-10 | Johann Dr Med Rull | Völlig tragmentationsfreie Kanülen |
| US6261272B1 (en) * | 1996-06-10 | 2001-07-17 | Elan Corporation, Plc | Needle for subcutaneous delivery of fluids |
| DE19717253A1 (de) * | 1997-04-24 | 1998-10-29 | Edwin Dr Med Klaus | Universal-Ideal-Nadel |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2498027C (en) | 2012-03-27 |
| AU2003273306A1 (en) | 2004-04-30 |
| US20040092893A1 (en) | 2004-05-13 |
| ATE363310T1 (de) | 2007-06-15 |
| WO2004024219A1 (en) | 2004-03-25 |
| EP1539281B1 (en) | 2007-05-30 |
| EP1539281A1 (en) | 2005-06-15 |
| DK1539281T3 (da) | 2007-10-01 |
| ES2287517T3 (es) | 2007-12-16 |
| DE60314157D1 (de) | 2007-07-12 |
| CA2498027A1 (en) | 2004-03-25 |
| DE60314157T2 (de) | 2008-01-31 |
| JP2005537893A (ja) | 2005-12-15 |
| US20050245895A1 (en) | 2005-11-03 |
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