AU2003251674B2 - Variants of the major allergen Phl p 1 from timothy grass - Google Patents

Variants of the major allergen Phl p 1 from timothy grass Download PDF

Info

Publication number
AU2003251674B2
AU2003251674B2 AU2003251674A AU2003251674A AU2003251674B2 AU 2003251674 B2 AU2003251674 B2 AU 2003251674B2 AU 2003251674 A AU2003251674 A AU 2003251674A AU 2003251674 A AU2003251674 A AU 2003251674A AU 2003251674 B2 AU2003251674 B2 AU 2003251674B2
Authority
AU
Australia
Prior art keywords
allergen
variant
timothy grass
rphl
phl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003251674A
Other languages
English (en)
Other versions
AU2003251674A1 (en
Inventor
Oliver Cromwell
Helmut Fiebig
Roland Suck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU2003251674A1 publication Critical patent/AU2003251674A1/en
Application granted granted Critical
Publication of AU2003251674B2 publication Critical patent/AU2003251674B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AU2003251674A 2002-08-19 2003-07-31 Variants of the major allergen Phl p 1 from timothy grass Ceased AU2003251674B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02018157.4 2002-08-19
EP02018157 2002-08-19
PCT/EP2003/008471 WO2004022588A1 (de) 2002-08-19 2003-07-31 Varianten des majorallergens phl p 1 aus lieschgras

Publications (2)

Publication Number Publication Date
AU2003251674A1 AU2003251674A1 (en) 2004-03-29
AU2003251674B2 true AU2003251674B2 (en) 2009-09-03

Family

ID=31970262

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003251674A Ceased AU2003251674B2 (en) 2002-08-19 2003-07-31 Variants of the major allergen Phl p 1 from timothy grass

Country Status (12)

Country Link
US (2) US7731970B2 (enExample)
EP (1) EP1532169B1 (enExample)
JP (2) JP4668616B2 (enExample)
CN (1) CN100509844C (enExample)
AU (1) AU2003251674B2 (enExample)
BR (1) BRPI0313613B1 (enExample)
CA (1) CA2495825C (enExample)
ES (1) ES2400181T3 (enExample)
PL (1) PL212891B1 (enExample)
PT (1) PT1532169E (enExample)
RU (1) RU2323942C2 (enExample)
WO (1) WO2004022588A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7731970B2 (en) * 2002-08-19 2010-06-08 Merck Patent Gmbh Variants of the major allergen Phl p 1 from timothy grass
DE102004035337A1 (de) * 2004-07-21 2006-03-16 Merck Patent Gmbh Varianten der Gruppe 1-Allergene aus Poaceae mit reduzierter Allergenität und erhaltener T-Zellreaktivität
BR112014019504A2 (pt) * 2012-02-07 2017-06-27 La Jolla Inst Allergy & Immunology alérgenos da erva-dos-prados e métodos e usos para modulação de resposta imune
JP6102442B2 (ja) * 2013-04-04 2017-03-29 日産自動車株式会社 リチウムイオン二次電池
CA3126499A1 (en) 2019-01-17 2020-07-23 LETI Pharma S.L. Methods of purifying an allergen extract

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2089735C (en) 1990-08-17 2008-03-18 Mohan Bir Singh Ryegrass pollen allergen
IL115177A0 (en) * 1994-09-16 1995-12-31 Immunomedics Inc Phosphorus-32 labeling of antibodies for cancer therapy
US6281332B1 (en) * 1994-12-02 2001-08-28 The Johns Hopkins University School Of Medicine Hedgehog-derived polypeptides
EP0966478A4 (en) * 1996-10-07 2002-08-21 Univ Johns Hopkins Med Novel hedgehog-derived polypeptides
JP2002500198A (ja) * 1998-01-09 2002-01-08 サーカシア リミテッド 脱感作のための方法及び組成物
DE19918682A1 (de) * 1999-04-23 2000-10-26 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung eines Graminaen-Allergens
US20070011783A1 (en) * 1999-05-06 2007-01-11 Jingdong Liu Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20100293669A2 (en) * 1999-05-06 2010-11-18 Jingdong Liu Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
IT1318692B1 (it) * 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti di proteine allergeniche di phleum pratense.
AU2002256276A1 (en) * 2001-04-19 2002-11-05 Penn State Research Foundation Novel expansin polynucleotides, related polypeptides and methods of use
US7731970B2 (en) * 2002-08-19 2010-06-08 Merck Patent Gmbh Variants of the major allergen Phl p 1 from timothy grass

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Focke, M. et al., The FASEB Journal (2001): 1-25 *

Also Published As

Publication number Publication date
JP2006516382A (ja) 2006-07-06
JP4668616B2 (ja) 2011-04-13
EP1532169B1 (de) 2012-12-19
PL373069A1 (en) 2005-08-08
CN1675240A (zh) 2005-09-28
BR0313613A (pt) 2005-06-21
US9453058B2 (en) 2016-09-27
US20060251682A1 (en) 2006-11-09
EP1532169A1 (de) 2005-05-25
CN100509844C (zh) 2009-07-08
JP5868587B2 (ja) 2016-02-24
PT1532169E (pt) 2013-03-18
CA2495825C (en) 2015-03-17
ES2400181T3 (es) 2013-04-08
JP2011097940A (ja) 2011-05-19
RU2005107782A (ru) 2005-11-20
US20120263741A1 (en) 2012-10-18
AU2003251674A1 (en) 2004-03-29
PL212891B1 (pl) 2012-12-31
CA2495825A1 (en) 2004-03-18
RU2323942C2 (ru) 2008-05-10
BRPI0313613B1 (pt) 2016-06-07
US7731970B2 (en) 2010-06-08
WO2004022588A1 (de) 2004-03-18

Similar Documents

Publication Publication Date Title
US8945530B2 (en) DNA sequence, and recombinant preparation of the grass pollen allergen Lol p4
US9453058B2 (en) Variants of the major allergen Phl P 1 from timothy grass
US20160207967A1 (en) Phl p 5a derivatives having reduced allergeneity and retained t-cell reactivity
JP3316535B2 (ja) ダニアレルゲンの改変体およびその製造法
CA2370393C (en) Dna sequence, and recombinant production of a gramineae allergen
US20170246317A1 (en) Dna sequence, and recombinant preparation of group 4 major allergens from cereals
JP4343702B2 (ja) 低アレルギー性シラカバ花粉主要アレルゲンrBetv1の製造方法
AU2001287695B2 (en) Method for purifying recombinant proteins expressed as insoluble aggregates
AU2013204574B2 (en) DNA-sequence and recombinant production of group 4 major allergens from cereals
AU2012205288B2 (en) DNA-sequence and recombinant production of group 4 major allergens from cereals

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired