AU2003251674B2 - Variants of the major allergen Phl p 1 from timothy grass - Google Patents

Variants of the major allergen Phl p 1 from timothy grass Download PDF

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Publication number
AU2003251674B2
AU2003251674B2 AU2003251674A AU2003251674A AU2003251674B2 AU 2003251674 B2 AU2003251674 B2 AU 2003251674B2 AU 2003251674 A AU2003251674 A AU 2003251674A AU 2003251674 A AU2003251674 A AU 2003251674A AU 2003251674 B2 AU2003251674 B2 AU 2003251674B2
Authority
AU
Australia
Prior art keywords
allergen
variant
timothy grass
rphl
phl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003251674A
Other languages
English (en)
Other versions
AU2003251674A1 (en
Inventor
Oliver Cromwell
Helmut Fiebig
Roland Suck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU2003251674A1 publication Critical patent/AU2003251674A1/en
Application granted granted Critical
Publication of AU2003251674B2 publication Critical patent/AU2003251674B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AU2003251674A 2002-08-19 2003-07-31 Variants of the major allergen Phl p 1 from timothy grass Ceased AU2003251674B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02018157.4 2002-08-19
EP02018157 2002-08-19
PCT/EP2003/008471 WO2004022588A1 (de) 2002-08-19 2003-07-31 Varianten des majorallergens phl p 1 aus lieschgras

Publications (2)

Publication Number Publication Date
AU2003251674A1 AU2003251674A1 (en) 2004-03-29
AU2003251674B2 true AU2003251674B2 (en) 2009-09-03

Family

ID=31970262

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003251674A Ceased AU2003251674B2 (en) 2002-08-19 2003-07-31 Variants of the major allergen Phl p 1 from timothy grass

Country Status (12)

Country Link
US (2) US7731970B2 (enExample)
EP (1) EP1532169B1 (enExample)
JP (2) JP4668616B2 (enExample)
CN (1) CN100509844C (enExample)
AU (1) AU2003251674B2 (enExample)
BR (1) BRPI0313613B1 (enExample)
CA (1) CA2495825C (enExample)
ES (1) ES2400181T3 (enExample)
PL (1) PL212891B1 (enExample)
PT (1) PT1532169E (enExample)
RU (1) RU2323942C2 (enExample)
WO (1) WO2004022588A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4668616B2 (ja) * 2002-08-19 2011-04-13 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング オオアワガエリからの主要アレルゲンＰｈｌｐ１の変異体
DE102004035337A1 (de) * 2004-07-21 2006-03-16 Merck Patent Gmbh Varianten der Gruppe 1-Allergene aus Poaceae mit reduzierter Allergenität und erhaltener T-Zellreaktivität
CN104203277A (zh) * 2012-02-07 2014-12-10 拉霍拉敏感及免疫学研究所 梯牧草变应原和用于调节免疫反应的方法和用途
JP6102442B2 (ja) * 2013-04-04 2017-03-29 日産自動車株式会社 リチウムイオン二次電池
AU2019422413B2 (en) * 2019-01-17 2026-05-14 LETI Pharma S.L. Methods of purifying an allergen extract

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU659801B2 (en) 1990-08-17 1995-06-01 University Of Melbourne, The Ryegrass pollen allergen
IL115177A0 (en) * 1994-09-16 1995-12-31 Immunomedics Inc Phosphorus-32 labeling of antibodies for cancer therapy
US6281332B1 (en) * 1994-12-02 2001-08-28 The Johns Hopkins University School Of Medicine Hedgehog-derived polypeptides
AU728541B2 (en) * 1996-10-07 2001-01-11 Johns Hopkins University School Of Medicine, The Novel hedgehog-derived polypeptides
CA2317724A1 (en) * 1998-01-09 1999-07-15 Circassia Limited Methods and compositions for desensitisation
DE19918682A1 (de) * 1999-04-23 2000-10-26 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung eines Graminaen-Allergens
US20070011783A1 (en) * 1999-05-06 2007-01-11 Jingdong Liu Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US20100293669A2 (en) * 1999-05-06 2010-11-18 Jingdong Liu Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
IT1318692B1 (it) 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti di proteine allergeniche di phleum pratense.
US7001743B2 (en) * 2001-04-19 2006-02-21 The Penn State Research Foundation Expansin polynucleotides, related polypeptides and methods of use
JP4668616B2 (ja) * 2002-08-19 2011-04-13 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング オオアワガエリからの主要アレルゲンＰｈｌｐ１の変異体

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Focke, M. et al., The FASEB Journal (2001): 1-25 *

Also Published As

Publication number Publication date
EP1532169B1 (de) 2012-12-19
PT1532169E (pt) 2013-03-18
PL373069A1 (en) 2005-08-08
JP2011097940A (ja) 2011-05-19
RU2323942C2 (ru) 2008-05-10
CN100509844C (zh) 2009-07-08
US20120263741A1 (en) 2012-10-18
US7731970B2 (en) 2010-06-08
PL212891B1 (pl) 2012-12-31
JP4668616B2 (ja) 2011-04-13
BRPI0313613B1 (pt) 2016-06-07
WO2004022588A1 (de) 2004-03-18
JP2006516382A (ja) 2006-07-06
AU2003251674A1 (en) 2004-03-29
CA2495825A1 (en) 2004-03-18
US20060251682A1 (en) 2006-11-09
RU2005107782A (ru) 2005-11-20
ES2400181T3 (es) 2013-04-08
US9453058B2 (en) 2016-09-27
JP5868587B2 (ja) 2016-02-24
EP1532169A1 (de) 2005-05-25
CN1675240A (zh) 2005-09-28
CA2495825C (en) 2015-03-17
BR0313613A (pt) 2005-06-21

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired