BR0313613A - Variantes do principal alérgeno phl p 1 de capim-timóteo - Google Patents
Variantes do principal alérgeno phl p 1 de capim-timóteoInfo
- Publication number
- BR0313613A BR0313613A BR0313613-2A BR0313613A BR0313613A BR 0313613 A BR0313613 A BR 0313613A BR 0313613 A BR0313613 A BR 0313613A BR 0313613 A BR0313613 A BR 0313613A
- Authority
- BR
- Brazil
- Prior art keywords
- phl
- timothy grass
- variants
- main
- main allergen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
"VARIANTES DO PRINCIPAL ALéRGENO PHL P1 DE CAPIM-TIMóTEO". A presente invenção refere-se a variantes do principal alérgeno Phl p 1 de capim-timóteo, caracterizadas pelo fato de que uma preparação, até então não possível, de moléculas monoméricas que são solúveis e estáveis no meio fisiológico, pode ser realizada com a ajuda de sistemas de expressão procariótica e subseq³ente purificação das mesmas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02018157 | 2002-08-19 | ||
PCT/EP2003/008471 WO2004022588A1 (de) | 2002-08-19 | 2003-07-31 | Varianten des majorallergens phl p 1 aus lieschgras |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0313613A true BR0313613A (pt) | 2005-06-21 |
BRPI0313613B1 BRPI0313613B1 (pt) | 2016-06-07 |
Family
ID=31970262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0313613A BRPI0313613B1 (pt) | 2002-08-19 | 2003-07-31 | variantes do principal alérgeno phl p 1 de capim-timóteo, suas formas de enovelamento lm e hm, seus usos e seus processos de preparação e de purificação, molécula de dna, vetor de expressão de dna recombinante e seu uso, e composições farmacêuticas |
Country Status (12)
Country | Link |
---|---|
US (2) | US7731970B2 (pt) |
EP (1) | EP1532169B1 (pt) |
JP (2) | JP4668616B2 (pt) |
CN (1) | CN100509844C (pt) |
AU (1) | AU2003251674B2 (pt) |
BR (1) | BRPI0313613B1 (pt) |
CA (1) | CA2495825C (pt) |
ES (1) | ES2400181T3 (pt) |
PL (1) | PL212891B1 (pt) |
PT (1) | PT1532169E (pt) |
RU (1) | RU2323942C2 (pt) |
WO (1) | WO2004022588A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7731970B2 (en) * | 2002-08-19 | 2010-06-08 | Merck Patent Gmbh | Variants of the major allergen Phl p 1 from timothy grass |
DE102004035337A1 (de) * | 2004-07-21 | 2006-03-16 | Merck Patent Gmbh | Varianten der Gruppe 1-Allergene aus Poaceae mit reduzierter Allergenität und erhaltener T-Zellreaktivität |
IN2014MN01513A (pt) * | 2012-02-07 | 2015-09-11 | Jolla Inst Allergy Immunolog | |
JP6102442B2 (ja) * | 2013-04-04 | 2017-03-29 | 日産自動車株式会社 | リチウムイオン二次電池 |
PE20212105A1 (es) * | 2019-01-17 | 2021-11-04 | Leti Pharma S L | Metodos para purificar un extracto de alergeno |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69128039T2 (de) * | 1990-08-17 | 1998-03-05 | Univ Melbourne | Allergene aus roggenspreupollen |
IL115177A0 (en) * | 1994-09-16 | 1995-12-31 | Immunomedics Inc | Phosphorus-32 labeling of antibodies for cancer therapy |
US6281332B1 (en) * | 1994-12-02 | 2001-08-28 | The Johns Hopkins University School Of Medicine | Hedgehog-derived polypeptides |
JP2002503088A (ja) * | 1996-10-07 | 2002-01-29 | ザ ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン | 新規ヘッジホッグ由来ポリペプチド |
CA2317724A1 (en) * | 1998-01-09 | 1999-07-15 | Circassia Limited | Methods and compositions for desensitisation |
US20100293669A2 (en) * | 1999-05-06 | 2010-11-18 | Jingdong Liu | Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement |
US20070011783A1 (en) * | 1999-05-06 | 2007-01-11 | Jingdong Liu | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
IT1318692B1 (it) * | 2000-09-12 | 2003-08-27 | Consiglio Nazionale Ricerche | Varianti di proteine allergeniche di phleum pratense. |
AU2002256276A1 (en) * | 2001-04-19 | 2002-11-05 | Penn State Research Foundation | Novel expansin polynucleotides, related polypeptides and methods of use |
US7731970B2 (en) * | 2002-08-19 | 2010-06-08 | Merck Patent Gmbh | Variants of the major allergen Phl p 1 from timothy grass |
-
2003
- 2003-07-31 US US10/525,000 patent/US7731970B2/en not_active Expired - Fee Related
- 2003-07-31 EP EP03793667A patent/EP1532169B1/de not_active Expired - Lifetime
- 2003-07-31 ES ES03793667T patent/ES2400181T3/es not_active Expired - Lifetime
- 2003-07-31 CA CA2495825A patent/CA2495825C/en not_active Expired - Lifetime
- 2003-07-31 RU RU2005107782/13A patent/RU2323942C2/ru not_active IP Right Cessation
- 2003-07-31 PL PL373069A patent/PL212891B1/pl unknown
- 2003-07-31 JP JP2004533298A patent/JP4668616B2/ja not_active Expired - Fee Related
- 2003-07-31 PT PT37936671T patent/PT1532169E/pt unknown
- 2003-07-31 AU AU2003251674A patent/AU2003251674B2/en not_active Ceased
- 2003-07-31 WO PCT/EP2003/008471 patent/WO2004022588A1/de active Application Filing
- 2003-07-31 CN CNB038198231A patent/CN100509844C/zh not_active Expired - Fee Related
- 2003-07-31 BR BRPI0313613A patent/BRPI0313613B1/pt not_active IP Right Cessation
-
2010
- 2010-03-22 US US12/728,745 patent/US9453058B2/en not_active Expired - Fee Related
- 2010-11-08 JP JP2010249581A patent/JP5868587B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2003251674A1 (en) | 2004-03-29 |
PL212891B1 (pl) | 2012-12-31 |
CA2495825C (en) | 2015-03-17 |
CN100509844C (zh) | 2009-07-08 |
WO2004022588A1 (de) | 2004-03-18 |
US9453058B2 (en) | 2016-09-27 |
CN1675240A (zh) | 2005-09-28 |
JP4668616B2 (ja) | 2011-04-13 |
US20060251682A1 (en) | 2006-11-09 |
BRPI0313613B1 (pt) | 2016-06-07 |
EP1532169A1 (de) | 2005-05-25 |
JP2006516382A (ja) | 2006-07-06 |
RU2323942C2 (ru) | 2008-05-10 |
JP2011097940A (ja) | 2011-05-19 |
US7731970B2 (en) | 2010-06-08 |
EP1532169B1 (de) | 2012-12-19 |
JP5868587B2 (ja) | 2016-02-24 |
RU2005107782A (ru) | 2005-11-20 |
ES2400181T3 (es) | 2013-04-08 |
AU2003251674B2 (en) | 2009-09-03 |
PL373069A1 (en) | 2005-08-08 |
CA2495825A1 (en) | 2004-03-18 |
PT1532169E (pt) | 2013-03-18 |
US20120263741A1 (en) | 2012-10-18 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
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Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06A | Notification to applicant to reply to the report for non-patentability or inadequacy of the application according art. 36 industrial patent law | ||
B06A | Notification to applicant to reply to the report for non-patentability or inadequacy of the application according art. 36 industrial patent law | ||
B09A | Decision: intention to grant | ||
B16A | Patent or certificate of addition of invention granted |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 07/06/2016, OBSERVADAS AS CONDICOES LEGAIS. |
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B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
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B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2473 DE 29-05-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |