AU2003226765A1 - Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents - Google Patents

Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents

Info

Publication number
AU2003226765A1
AU2003226765A1 AU2003226765A AU2003226765A AU2003226765A1 AU 2003226765 A1 AU2003226765 A1 AU 2003226765A1 AU 2003226765 A AU2003226765 A AU 2003226765A AU 2003226765 A AU2003226765 A AU 2003226765A AU 2003226765 A1 AU2003226765 A1 AU 2003226765A1
Authority
AU
Australia
Prior art keywords
azaindolylpiperidine
antihistaminic
derivatives
antiallergic agents
antiallergic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003226765A
Other languages
English (en)
Other versions
AU2003226765A8 (en
Inventor
Aranzazu Cardus Figueras
Silvia Fonquerna Pou
Luis Miguel Pages Santacana
Carlos Puig Duran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almirall SA
Original Assignee
Almirall Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma SA filed Critical Almirall Prodesfarma SA
Publication of AU2003226765A8 publication Critical patent/AU2003226765A8/xx
Publication of AU2003226765A1 publication Critical patent/AU2003226765A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2003226765A 2002-04-01 2003-04-01 Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents Abandoned AU2003226765A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP200200753 2002-04-01
ES200200753A ES2201899B1 (es) 2002-04-01 2002-04-01 Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
PCT/EP2003/003377 WO2003082867A1 (en) 2002-04-01 2003-04-01 Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents

Publications (2)

Publication Number Publication Date
AU2003226765A8 AU2003226765A8 (en) 2003-10-13
AU2003226765A1 true AU2003226765A1 (en) 2003-10-13

Family

ID=28459671

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003226765A Abandoned AU2003226765A1 (en) 2002-04-01 2003-04-01 Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents

Country Status (10)

Country Link
US (1) US7622480B2 (enExample)
EP (1) EP1497292B1 (enExample)
JP (1) JP2005526816A (enExample)
AT (1) ATE329916T1 (enExample)
AU (1) AU2003226765A1 (enExample)
DE (1) DE60306138T2 (enExample)
DK (1) DK1497292T3 (enExample)
ES (2) ES2201899B1 (enExample)
PT (1) PT1497292E (enExample)
WO (1) WO2003082867A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06004626A (es) * 2003-11-17 2006-06-27 Boehringer Ingelheim Int Indoles sustituidos con piperidina o sus heteroderivados y su uso como moduladores del receptor de quemocina (ccr3).
ATE461925T1 (de) * 2005-04-26 2010-04-15 Hypnion Inc Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
WO2006117314A2 (en) * 2005-04-30 2006-11-09 Boehringer Ingelheim International Gmbh Novel piperidin- substituted indoles and their use as ccr-3 modulators
WO2007050381A2 (en) * 2005-10-24 2007-05-03 Janssen Pharmaceutica, N.V. 3-piperidin-4-yl-indole orl-1 receptor modulators
ATE537166T1 (de) * 2006-10-27 2011-12-15 Boehringer Ingelheim Int Piperidylpropanthiole als ccr3-modulatoren
WO2008049875A1 (en) * 2006-10-27 2008-05-02 Boehringer Ingelheim International Gmbh Novel substituted piperidyl-propane-thiols
JP2014515368A (ja) 2011-05-26 2014-06-30 第一三共株式会社 プロテインキナーゼ阻害剤としての複素環化合物
MA40759A (fr) 2014-09-26 2017-08-01 Pfizer Modulateurs de rorc2 de type pyrrolopyridine substitué par un méthyle et trifluorométhyle et leurs procédés d'utilisation
CA3081443A1 (en) 2014-12-15 2016-06-23 The Regents Of The University Of Michigan Small molecule inhibitors of egfr and pi3k
KR101660863B1 (ko) * 2015-04-03 2016-09-28 주식회사 녹십자 IKKε 및 TBK1 억제제로서의 7-아자인돌 또는 4,7-다이아자인돌 유도체 및 이를 포함하는 약학적 조성물
US11673876B2 (en) 2020-12-22 2023-06-13 Mekanistic Therapeutics Llc Substituted aminobenzyl heteroaryl compounds as EGFR and/or PI3K inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2086112A1 (en) * 1991-04-23 1992-10-24 Katsuhiro Shibayama Tricyclic triazolo derivatives, processes for producing the same and uses of the same
AU3176297A (en) * 1996-06-25 1998-01-14 Novartis Ag Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof
ZA979961B (en) * 1996-11-15 1999-05-05 Lilly Co Eli 5-HT1F agonists
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
HK1052705B (en) * 2000-08-14 2006-09-29 Ortho-Mcneil Pharmaceutical, Inc. Substituted pyrazole
ATE402699T1 (de) 2000-09-06 2008-08-15 Ortho Mcneil Pharm Inc Verwendung von substituierten pyrazolen zur behandlung von allergien
ES2172436B1 (es) * 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
EA200300717A1 (ru) 2000-12-22 2003-12-25 Уайт Гетероциклилиндазольные и -азаиндазольные соединения в качестве 5-гидрокситриптамин-6-лигандов
WO2002079151A1 (en) 2001-03-29 2002-10-10 Smithkline Beecham P.L.C. 3-substituted indoels or fused pyrroles as antagonists of the chemokine mcp-1 (ccr2b) receptor

Also Published As

Publication number Publication date
WO2003082867A1 (en) 2003-10-09
DE60306138D1 (de) 2006-07-27
US20050176751A1 (en) 2005-08-11
PT1497292E (pt) 2006-10-31
WO2003082867A8 (en) 2004-11-04
US7622480B2 (en) 2009-11-24
ATE329916T1 (de) 2006-07-15
JP2005526816A (ja) 2005-09-08
AU2003226765A8 (en) 2003-10-13
EP1497292B1 (en) 2006-06-14
ES2201899B1 (es) 2005-06-01
ES2265577T3 (es) 2007-02-16
ES2201899A1 (es) 2004-03-16
DK1497292T3 (da) 2006-10-16
EP1497292A1 (en) 2005-01-19
DE60306138T2 (de) 2007-05-03

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase