ATE329916T1 - Azaindolylpiperidinderivate als antihistaminika und antiallergika - Google Patents

Azaindolylpiperidinderivate als antihistaminika und antiallergika

Info

Publication number
ATE329916T1
ATE329916T1 AT03745302T AT03745302T ATE329916T1 AT E329916 T1 ATE329916 T1 AT E329916T1 AT 03745302 T AT03745302 T AT 03745302T AT 03745302 T AT03745302 T AT 03745302T AT E329916 T1 ATE329916 T1 AT E329916T1
Authority
AT
Austria
Prior art keywords
azaindolylpiperidine
anthistaminics
antiallergics
derivatives
therapy
Prior art date
Application number
AT03745302T
Other languages
English (en)
Inventor
Pou Silvia Fonquerna
Santacana Luis Miguel Pages
Duran Carlos Puig
Figueras Aranzazu Cardus
Soto Jose Manuel Prieto
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Application granted granted Critical
Publication of ATE329916T1 publication Critical patent/ATE329916T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03745302T 2002-04-01 2003-04-01 Azaindolylpiperidinderivate als antihistaminika und antiallergika ATE329916T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200200753A ES2201899B1 (es) 2002-04-01 2002-04-01 Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.

Publications (1)

Publication Number Publication Date
ATE329916T1 true ATE329916T1 (de) 2006-07-15

Family

ID=28459671

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03745302T ATE329916T1 (de) 2002-04-01 2003-04-01 Azaindolylpiperidinderivate als antihistaminika und antiallergika

Country Status (10)

Country Link
US (1) US7622480B2 (de)
EP (1) EP1497292B1 (de)
JP (1) JP2005526816A (de)
AT (1) ATE329916T1 (de)
AU (1) AU2003226765A1 (de)
DE (1) DE60306138T2 (de)
DK (1) DK1497292T3 (de)
ES (2) ES2201899B1 (de)
PT (1) PT1497292E (de)
WO (1) WO2003082867A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2545261C (en) * 2003-11-17 2013-07-23 Boehringer Ingelheim International Gmbh Piperidine-substituted indoles- or heteroderivatives thereof
EP1877405B1 (de) * 2005-04-26 2010-03-03 Hypnion, Inc. Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
JP5080450B2 (ja) * 2005-04-30 2012-11-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規なピペリジン置換インドール
JP2009515833A (ja) * 2005-10-24 2009-04-16 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ３−ピペリジン−４−イル−インドールｏｒｌ−１受容体モジュレーター
WO2008049874A1 (en) * 2006-10-27 2008-05-02 Boehringer Ingelheim International Gmbh Piperidyl-propane-thiol ccr3 modulators
JP5657253B2 (ja) * 2006-10-27 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規な置換ピペリジル−プロパン−チオール
JP2014515368A (ja) * 2011-05-26 2014-06-30 第一三共株式会社 プロテインキナーゼ阻害剤としての複素環化合物
MA40759A (fr) 2014-09-26 2017-08-01 Pfizer Modulateurs de rorc2 de type pyrrolopyridine substitué par un méthyle et trifluorométhyle et leurs procédés d'utilisation
CA2969974C (en) 2014-12-15 2020-08-04 The Regents Of The University Of Michigan Small molecule inhibitors of egfr and pi3k
KR101660863B1 (ko) * 2015-04-03 2016-09-28 주식회사 녹십자 IKKε 및 TBK1 억제제로서의 7-아자인돌 또는 4,7-다이아자인돌 유도체 및 이를 포함하는 약학적 조성물
EP4267554A1 (de) 2020-12-22 2023-11-01 Mekanistic Therapeutics LLC Substituierte aminobenzylheteroarylverbindungen als egfr- und/oder pi3k-hemmer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69230125T2 (de) * 1991-04-23 2000-02-03 Toray Industries Tricyclische triazolderivate, ihre herstellung und ihre verwendung
AU3176297A (en) * 1996-06-25 1998-01-14 Novartis Ag Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof
ZA979961B (en) * 1996-11-15 1999-05-05 Lilly Co Eli 5-HT1F agonists
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
US6635633B2 (en) * 2000-08-14 2003-10-21 Ortho-Pharmaceutical, Inc. Substituted pyrazoles
DK1315492T3 (da) * 2000-09-06 2008-10-13 Ortho Mcneil Pharm Inc Anvendelse af substituerede pyrazoler til behandling af allergier
ES2172436B1 (es) * 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
HUP0400684A2 (hu) 2000-12-22 2004-07-28 Wyeth 5-Hidroxitriptamin-6-ligandumként használható heterociklilindazol- és -azaindazol-származékok, előállításuk és ezeket tartalmazó gyógyszerkészítmények
WO2002079151A1 (en) 2001-03-29 2002-10-10 Smithkline Beecham P.L.C. 3-substituted indoels or fused pyrroles as antagonists of the chemokine mcp-1 (ccr2b) receptor

Also Published As

Publication number Publication date
WO2003082867A1 (en) 2003-10-09
AU2003226765A8 (en) 2003-10-13
DK1497292T3 (da) 2006-10-16
JP2005526816A (ja) 2005-09-08
PT1497292E (pt) 2006-10-31
DE60306138D1 (de) 2006-07-27
EP1497292B1 (de) 2006-06-14
EP1497292A1 (de) 2005-01-19
US7622480B2 (en) 2009-11-24
ES2201899A1 (es) 2004-03-16
AU2003226765A1 (en) 2003-10-13
WO2003082867A8 (en) 2004-11-04
ES2265577T3 (es) 2007-02-16
US20050176751A1 (en) 2005-08-11
ES2201899B1 (es) 2005-06-01
DE60306138T2 (de) 2007-05-03

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